Deciphering Repertoire of B16 Melanoma Reactive TCRs by Immunization, In Vitro Restimulation and Sequencing of IFNγ-Secreting T Cells

Autor: Dmitry M. Chudakov, Valeria D. Skatova, Elena V. Zagainova, Anna V. Izosimova, Diana V. Yuzhakova, Lilia N Volchkova, George V. Sharonov

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9859, p 9859 (2021)

Recent advances in cancer immunotherapy have great promise for the treatment of solid tumors. One of the key limiting factors that hamper the decoding of physiological responses to these therapies is the inability to distinguish between specific and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd13509ff99f3b67ab75d9e26d337f0

Nanoparticles as contrast-enhancing agents in optical coherence tomography imaging of the structural components of skin: Quantitative evaluation

Autor: V A Kamenskii, Elena V. Zagainova, M. Yu. Kirillin, P. D. Agrba, M V Shiryamova, Marina A. Sirotkina

Publikováno v: Quantum Electronics. 40:525-530

This work examines the effect of gold nanoshells and titania nanoparticles on the imaging contrast of structural components of skin in optical coherence tomography (OCT). Experimental data are compared to Monte Carlo (MC) simulation results. In exper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5386859525ebf6b73430e1c04f524ca
https://doi.org/10.1070/qe2010v040n06abeh014294

Trans-illumination fluorescence imaging of deep-seated tumors in small animals

Autor: V. I. Plekhanov, Anna Orlova, Marina V. Shirmanova, Ilya V. Turchin, Ilya I. Fiks, M S Kleshnin, Sergey Lukyanov, Elena V. Zagainova

Publikováno v: Photonics & Lasers in Medicine. 4

Background:Fluorescence diffuse tomography (FDT) is the most accurate technique for the imaging of labeled tumors in the small animal body. However, the procedure for reconstruction of the spatial distribution of the fluorophore requires a high signa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f76799790df4e564b6d4e5ce8e7368c
https://doi.org/10.1515/plm-2014-0024

Study of photosensitizers pharmacokinetics in mouse tumor model by transillumination fluorescence imaging in vivo

Autor: Elena V. Zagainova, Natalya Yu. Lekanova, Marina V. Shirmanova, Marina A. Sirotkina, Irina V. Balalaeva, Ilya V. Turchin

Publikováno v: SPIE Proceedings.

In this work we demonstrate an efficiency of transillumination fluorescence imaging for intravital study of photosensitizers pharmacokinetics in tumor-bearing mice. Experiments were performed on CBA mice with subcutaneously transplanted cervical carc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1748222ee99b6410fa2fd6cc6a9f4c9a
https://doi.org/10.1117/12.873870

Plasmon resonance gold nanoparticles for improving optical diagnostics and photothermal therapy of tumor

Autor: Mikhail Yu. Kirillin, Marina V. Shirmanova, Marina A. Sirotkina, Victor A. Nadtochenko, P. D. Agrba, Vladislav A. Kamensky, Vadim Elagin, Elena V. Zagainova

Publikováno v: SPIE Proceedings.

The study was performed on 16 CBA-line female mice with transplanted cervical cancer. 0.2 ml of gold nanoparticle solution with a concentration of 10 9 particles/ml were injected into the animals intravenously. The particles were 200-250 nm in size;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c135d8ff969967cc8dc29eaceafdeac1
https://doi.org/10.1117/12.840638