Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Elena V. Shmendel"'
Autor:
Artem G. Fedorovskiy, Denis N. Antropov, Anton S. Dome, Pavel A. Puchkov, Daria M. Makarova, Maria V. Konopleva, Anastasiya M. Matveeva, Eugenia A. Panova, Elena V. Shmendel, Mikhail A. Maslov, Sergey E. Dmitriev, Grigory A. Stepanov, Oleg V. Markov
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 684 (2024)
Over the past decade, mRNA-based therapy has displayed significant promise in a wide range of clinical applications. The most striking example of the leap in the development of mRNA technologies was the mass vaccination against COVID-19 during the pa
Externí odkaz:
https://doaj.org/article/fabd7a7db29d4126993439ce312d430e
Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA
Autor:
Ali Bishani, Darya M. Makarova, Elena V. Shmendel, Mikhail A. Maslov, Aleksandra V. Sen‘kova, Innokenty A. Savin, Daniil V. Gladkikh, Marina A. Zenkova, Elena L. Chernolovskaya
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2184 (2023)
In this study, the impact of different delivery systems on the cytokine-inducing, antiproliferative, and antitumor activities of short immunostimulatory double-stranded RNA (isRNA) was investigated. The delivery systems, consisting of the polycationi
Externí odkaz:
https://doaj.org/article/59a02d77ecb24d2b8dd56541fe8cdb95
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1400 (2023)
The delivery of therapeutic nucleic acids is a prospective method for the treatment of both inherited and acquired diseases including cancer. To achieve maximal delivery efficiency and selectivity, nucleic acids should be targeted to the cells of int
Externí odkaz:
https://doaj.org/article/9d3dd266169744a39530d2a5ff4a1dd0
Autor:
Oleg V. Markov, Aleksandra V. Sen’kova, Islam S. Mohamed, Elena V. Shmendel, Mikhail A. Maslov, Anastasiya L. Oshchepkova, Evgeniy V. Brenner, Nadezhda L. Mironova, Marina A. Zenkova
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2542 (2022)
Cell-free antitumor vaccines represent a promising approach to immunotherapy of cancer. Here, we compare the antitumor potential of cell-free vaccines based on microvesicles derived from dendritic cells (DCs) with DC- and cationic-liposome-based vacc
Externí odkaz:
https://doaj.org/article/eb3ad4ee0c254b07bea709de01437fb6
Autor:
Maria E. Nikolaeva, Andrey V. Nechaev, Elena V. Shmendel, Roman A. Akasov, Mikhail A. Maslov, Andrey F. Mironov
Publikováno v:
Molecules, Vol 27, Iss 9, p 2763 (2022)
Upconverting nanoparticles have unique spectral and photophysical properties that make them suitable for development of theranostics for imaging and treating large and deep-seated tumors. Nanoparticles based on NaYF4 crystals doped with lanthanides Y
Externí odkaz:
https://doaj.org/article/b9ddc7e21fe643919a3a1d1b2a30ed22
Autor:
Daniil V. Gladkikh, Aleksandra V. Sen′kova, Ivan V. Chernikov, Tatyana O. Kabilova, Nelly A. Popova, Valery P. Nikolin, Elena V. Shmendel, Mikhail A. Maslov, Valentin V. Vlassov, Marina A. Zenkova, Elena L. Chernolovskaya
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1252 (2021)
In this study, we examined the in vivo toxicity of the liposomes F consisting of 1,26-bis(cholest-5-en-3-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride, lipid-helper 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine and folate lipoco
Externí odkaz:
https://doaj.org/article/df1d1da4a6b245aa93611c072a0d6e74
Autor:
Pavel A. Puchkov, Elena V. Shmendel, Valeria D. Andreeva, Nina G. Morozova, Marina A. Zenkova, Mikhail A. Maslov
Publikováno v:
Molbank, Vol 2018, Iss 1, p M981 (2018)
The absence of highly effective delivery systems is a major challenge for gene therapy. Our work was aimed at the development of novel cationic liposomes possessing high transfection efficiency. For this purpose, a novel disulfide polycationic amphip
Externí odkaz:
https://doaj.org/article/4221d223ce594fe384a826e139024173
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:1034-1042
Gene therapy is a promising method for the treatment of various diseases by introducing therapeutic nucleic acids, for the delivery of which cationic liposomes are widely used. This work demonstrates the ability of cationic liposomes composed of a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29fcb24b499bf577e218ce2f85b0862e
https://doi.org/10.1134/s1068162021050319
https://doi.org/10.1134/s1068162021050319
Autor:
E. A. Varlamova, M. A. Maslov, A. K. Isagulieva, Elena V. Shmendel, Alexander A. Shtil, N. G. Morozova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:965-979
The main classes of antitumor drugs (antimetabolites, anthracyclines, taxanes, and alkylating agents) act via DNA damage, inhibit DNA synthesis, and/or represent antimicrotubule agents. The phosphorus-containing alkyl glycerolipids induce death of tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b32073a077287a657b06c8c8f43fdc23
https://doi.org/10.1134/s1068162021050356
https://doi.org/10.1134/s1068162021050356
Autor:
Elena L. Chernolovskaya, Marina A. Zenkova, D. M. Makarova, Ivan V. Chernikov, Elena V. Shmendel, N. G. Morozova, S. A. Bakhareva, M. A. Maslov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 46:1250-1260
New uncharged gemini-amphiphiles have been synthesized. A series of cationic liposomes based on the polycationic amphiphile 1,26-bis(cholest-5-en-3β-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride (2X3), 1,2-dioleoyl-sn-glycero-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba19d55c133999901636f9ce3281fbc8
https://doi.org/10.1134/s106816202006031x
https://doi.org/10.1134/s106816202006031x