Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elena V. Salimova"'
Autor:
Mikhail V. Dubinin, Anna I. Ilzorkina, Elena V. Salimova, Manish S. Landage, Ekaterina I. Khoroshavina, Sergey V. Gudkov, Konstantin N. Belosludtsev, Lyudmila V. Parfenova
Publikováno v:
Membranes, Vol 13, Iss 10, p 835 (2023)
The paper assesses the membranotropic action of the natural antibiotic fusidic acid (FA) and its derivatives. It was found that a FA analogue with ethylenediamine moiety (derivative 2), in contrast to native FA and 3,11-dioxime analogue (derivative 1
Externí odkaz:
https://doaj.org/article/cfe549a4c290421195912f0c234c1bfb
Autor:
Elena V. Salimova, Oleg S. Mozgovoj, Svetlana S. Efimova, Olga S. Ostroumova, Lyudmila V. Parfenova
Publikováno v:
Membranes, Vol 13, Iss 3, p 309 (2023)
Fusidic acid (FA) is an antibiotic with high activity against Staphylococcus aureus; it has been used in clinical practice since the 1960s. However, the narrow antimicrobial spectrum of FA limits its application in the treatment of bacterial infectio
Externí odkaz:
https://doaj.org/article/4a15aec0c2434c3ab2982583a0ac2f45
Autor:
Elena V. Salimova, Lyudmila V. Parfenova, Diana V. Ishmetova, Liana F. Zainullina, Yulia V. Vakhitova
Mannich bases (8 examples) were synthesized via aminomethylation of fusidane propargyl esters. In vitro antimicrobial screening against key ESKAPE pathogens showed that the fusidic acid based Mannich products exhibit a high antimicrobial effect again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffbecc99c01ba3e417d8dabf862e865
Publikováno v:
Natural product communications. 11(3)
Acetylation of the 3,4-seco-derivatives of betulin, allobetulin and 28-oxyallobetulone gave the 5,19-(2,6-dimethylpyridin-4-yl)-4,23,24,20,29,30-hexanorlupane, and 5-(2,6-dimethylpyridin-4-yl)-4,23,24-trisnor-derivatives of oleanane and ursane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::568650b9160fdb1094367ef32e04f1cb
https://pubmed.ncbi.nlm.nih.gov/27169186
https://pubmed.ncbi.nlm.nih.gov/27169186
Publikováno v:
Natural product communications. 11(1)
Oximation of the dihydroquinopimaric acid O-cyanoethylderivative (2) via the amidoxime 3, and cyclization with trifluoroacetic anhydride resulted in a new 1,2,4-oxadiazole diterpenoid (4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27f64a9ad0b88a1b0126e56bb05e7ce8
https://pubmed.ncbi.nlm.nih.gov/26996010
https://pubmed.ncbi.nlm.nih.gov/26996010