Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elena V. Linardopoulou"'
Autor:
Elena V Linardopoulou, Sean S Parghi, Cynthia Friedman, Gregory E Osborn, Susan M Parkhurst, Barbara J Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e237 (2007)
Subtelomeres are duplication-rich, structurally variable regions of the human genome situated just proximal of telomeres. We report here that the most terminally located human subtelomeric genes encode a previously unrecognized third subclass of the
Externí odkaz:
https://doaj.org/article/aabc5285b1f84d54aab6db1a45e4785e
Autor:
M Katharine Rudd, Cynthia Friedman, Sean S Parghi, Elena V Linardopoulou, Li Hsu, Barbara J Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 2, p e32 (2007)
Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telo
Externí odkaz:
https://doaj.org/article/adef68cc10b94e048e4721a4001415e4
Publikováno v:
International Journal of Systematic and Evolutionary Microbiology. 67:3846-3853
A recent study of a group of Burkholderia glathei -like bacteria resulted in the description of 13 novel species of the genus Burkholderia . However, our analysis of phylogenetic positions of these species and their molecular signatures (conserved pr
Autor:
Xuan Qin, Susan M. Butler-Wu, Pavel Aprikian, Angus Toland, Peggy Rogers, Kim Riddell, James R. Johnson, Ajit P. Limaye, Evgeni V. Sokurenko, Brian D. Johnston, Mariya Billig, Scott J. Weissman, Barbara C. Kahl, Irina Igusheva, Delia Scholes, Alena Gileva, Elena V. Linardopoulou, Pacita L. Roberts, Brad T. Cookson, Sujay Chattopadhyay, Ferric C. Fang, Veronika Skrivankova, Veronika Tchesnokova, Lance B. Price
Publikováno v:
Journal of Clinical Microbiology. 51:2991-2999
The ability to identify bacterial pathogens at the subspecies level in clinical diagnostics is currently limited. We investigated whether splitting Escherichia coli species into clonal groups (clonotypes) predicts antimicrobial susceptibility or clin
Autor:
James R. Johnson, Veronika Tchesnokova, Mariya Billig, Evgeni V. Sokurenko, Sandip Paul, Lance B. Price, Elena V. Linardopoulou, Sujay Chattopadhyay
The contribution of homologous exchange (recombination) of core genes in the adaptive evolution of bacterial pathogens is not well understood. To investigate this, we analyzed fully assembled genomes of two Escherichia coli strains from sequence type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639ecb390600d55bd021241ecb0f4cce
https://europepmc.org/articles/PMC3553836/
https://europepmc.org/articles/PMC3553836/
Autor:
Dagmara I. Kisiela, Evgeni V. Sokurenko, Sandip Paul, Sujay Chattopadhyay, Elena V. Linardopoulou
One of the strongest signals of adaptive molecular evolution of proteins is the occurrence of convergent hot spot mutations: repeated changes in the same amino acid positions. We performed a comparative genome-wide analysis of mutation-driven evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be02f8bc39f604cf2b3cb85a6d1a365c
https://europepmc.org/articles/PMC3430314/
https://europepmc.org/articles/PMC3430314/
Autor:
Raymond Liu, Elena V. Linardopoulou, Kevin C. Barry, Gregory E. Osborn, Maria Teresa Abreu-Blanco, Susan M. Parkhurst
Publikováno v:
Development (Cambridge, England). 136(16)
Wiskott-Aldrich Syndrome (WAS) family proteins are Arp2/3 activators that mediate the branched-actin network formation required for cytoskeletal remodeling, intracellular transport and cell locomotion. Wasp and Scar/WAVE,the two founding members of t
Autor:
Cynthia Friedman, Li Hsu, M. Katharine Rudd, Elena V. Linardopoulou, Sean S Parghi, Barbara J. Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 2, p e32 (2007)
PLoS Genetics
PLoS Genetics
Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telo
Autor:
Cynthia Friedman, Lee Rowen, Leroy Hood, Scott Bloom, Barbara J. Trask, Amardeep Kaur, Eleanor M. Williams, Gustavo Glusman, Cecilie Boysen, Elena V. Linardopoulou, Shizhen Qin, Mary Ellen Ahearn, Kai Wang, Jason Seto
Publikováno v:
Molecular biology and evolution. 22(8)
Homo sapiens possess several trypsinogen or trypsinogen-like genes of which three (PRSS1, PRSS2, and PRSS3) produce functional trypsins in the digestive tract. PRSS1 and PRSS2 are located on chromosome 7q35, while PRSS3 is found on chromosome 9p13. H
Autor:
Eleanor M. Williams, Barbara J. Trask, Elena V. Linardopoulou, Cynthia Friedman, Yuxin Fan, Janet M. Young
Publikováno v:
Nature. 437(7055)
Human subtelomeres are polymorphic patchworks of interchromosomal segmental duplications at the ends of chromosomes. Here we provide evidence that these patchworks arose recently through repeated translocations between chromosome ends. We assess the