Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elena V. Kaznacheyeva"'
Publikováno v:
Life, Vol 14, Iss 3, p 357 (2024)
The incidence and development of cancer are highly dependent on pathological disturbances in calcium homeostasis of the cell. One of the major pathways for calcium entry is store-operated calcium entry (SOCE), which functions in virtually all cell ty
Externí odkaz:
https://doaj.org/article/fc3f605c0bb04b0bb68abba510595034
Autor:
Vladimir A. Vigont, Dmitriy A. Grekhnev, Olga S. Lebedeva, Konstantin O. Gusev, Egor A. Volovikov, Anton Yu. Skopin, Alexandra N. Bogomazova, Lilia D. Shuvalova, Olga A. Zubkova, Ekaterina A. Khomyakova, Lyubov N. Glushankova, Sergey A. Klyushnikov, Sergey N. Illarioshkin, Maria A. Lagarkova, Elena V. Kaznacheyeva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Huntington's disease (HD) is a severe autosomal-dominant neurodegenerative disorder caused by a mutation within a gene, encoding huntingtin protein. Here we have used the induced pluripotent stem cell technology to produce patient-specific terminally
Externí odkaz:
https://doaj.org/article/9dcef62d71f843a29c5597b140dec61c
Autor:
Magdalena Czeredys, Vladimir A. Vigont, Vasilisa A. Boeva, Katsuhiko Mikoshiba, Elena V. Kaznacheyeva, Jacek Kuznicki
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Huntington’s disease (HD) is a hereditary neurodegenerative disease that is caused by polyglutamine expansion within the huntingtin (HTT) gene. One of the cellular activities that is dysregulated in HD is store-operated calcium entry (SOCE), a proc
Externí odkaz:
https://doaj.org/article/c7e5689de540475f80284f94549c32ff
Autor:
Dmitriy A. Grekhnev, Iuliia V. Novikova, Alena V. Krisanova, Valeriy N. Yuskovets, Nikita M. Chernov, Igor P. Yakovlev, Elena V. Kaznacheyeva, Vladimir A. Vigont
Publikováno v:
Biochemical and Biophysical Research Communications. 626:38-43
Pathological calcium homeostasis accompanies the development of a large number of different diseases, therefore, the search for new modulators of calcium signaling remains highly actual. Last decades store-operated calcium channels have been repeated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588b6bfaa20be6bd280d0263dbded6c9
https://doi.org/10.1016/j.bbrc.2022.08.001
https://doi.org/10.1016/j.bbrc.2022.08.001
Autor:
Olga S. Lebedeva, Elena I. Sharova, Dmitriy A. Grekhnev, Liubov O. Skorodumova, Irina V. Kopylova, Ekaterina M. Vassina, Arina Oshkolova, Iuliia V. Novikova, Alena V. Krisanova, Evgenii I. Olekhnovich, Vladimir A. Vigont, Elena V. Kaznacheyeva, Alexandra N. Bogomazova, Maria A. Lagarkova
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7297
About 15% of patients with parkinsonism have a hereditary form of Parkinson’s disease (PD). Studies on the early stages of PD pathogenesis are challenging due to the lack of relevant models. The most promising ones are models based on dopaminergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98c13d180b86fa92ba464bc7dbea7ea
Publikováno v:
International Journal of Molecular Sciences. 23:15724
Quinazoline derivatives have various pharmacological activities and are widely used in clinical practice. Here, we reviewed the proposed mechanisms of the physiological activity of the quinazoline derivative EVP4593 and perspectives for its clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3149dddc417f900f13ae08963cbb96d2
https://doi.org/10.3390/ijms232415724
https://doi.org/10.3390/ijms232415724
Publikováno v:
Molecular neurobiology. 58(8)
Impairment of proteostasis network is one of the characteristic features of many age-related neurodegenerative disorders including autosomal dominantly inherited Huntington’s disease (HD). In HD, N-terminal portion of mutant huntingtin protein cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee4e891ee81448ea5a92c99219cfa06
https://pubmed.ncbi.nlm.nih.gov/33904021
https://pubmed.ncbi.nlm.nih.gov/33904021