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Autor:
Vadim B. Vasilyev, Oksana V. Kidgotko, Elena V. Grachyova, Vassilina A. Sokolova, Mikhail G. Bass, Maria E. Kustova, Alexander V. Sorokin
Publikováno v:
Biochimica et biophysica acta. 1757(5-6)
Gross alterations in cell energy metabolism underlie manifestations of hereditary OXPHOS (oxidative phosphorylation) diseases, many of which depend on proportion of mutant mitochondrial DNA (mtDNA) in tissues. An animal model of OXPHOS disease with m