Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elena V Dorofeeva"'
Intramolecular Hydrogen Bonding in N6-Substituted 2-Chloroadenosines: Evidence from NMR Spectroscopy
Autor:
Maria Ya. Berzina, Barbara Z. Eletskaya, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ilya V. Fateev, Olga N. Zhavoronkova, Arthur R. Bashorin, Alexandra O. Arnautova, Olga S. Smirnova, Konstantin V. Antonov, Alexander S. Paramonov, Maxim A. Dubinnyi, Roman S. Esipov, Anatoly I. Miroshnikov, Irina D. Konstantinova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9697 (2023)
Two forms were found in the NMR spectra of N6-substituted 2-chloroadenosines. The proportion of the mini-form was 11–32% of the main form. It was characterized by a separate set of signals in COSY, 15N-HMBC and other NMR spectra. We assumed that th
Externí odkaz:
https://doaj.org/article/c39dc45950364611958e951f8606b166
Autor:
Barbara Z. Eletskaya, Maria Ya. Berzina, Ilya V. Fateev, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ekaterina A. Zorina, Konstantin V. Antonov, Alexander S. Paramonov, Inessa S. Muzyka, Olga S. Zhukova, Mikhail V. Kiselevskiy, Anatoly I. Miroshnikov, Roman S. Esipov, Irina D. Konstantinova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6223 (2023)
A number of purine arabinosides containing chiral amino acid amides at the C6 position of the purine were synthesized using a transglycosylation reaction with recombinant E. coli nucleoside phosphorylases. Arsenolysis of 2-chloropurine ribosides with
Externí odkaz:
https://doaj.org/article/f29fcfdbffac4cb9834047e3156d7761
Intramolecular Hydrogen Bonding in N6-Substituted 2-Chloroadenosines: Evidence from NMR Spectroscopy
Autor:
Konstantinova, Maria Ya. Berzina, Barbara Z. Eletskaya, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ilya V. Fateev, Olga N. Zhavoronkova, Arthur R. Bashorin, Alexandra O. Arnautova, Olga S. Smirnova, Konstantin V. Antonov, Alexander S. Paramonov, Maxim A. Dubinnyi, Roman S. Esipov, Anatoly I. Miroshnikov, Irina D.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9697
Two forms were found in the NMR spectra of N6-substituted 2-chloroadenosines. The proportion of the mini-form was 11–32% of the main form. It was characterized by a separate set of signals in COSY, 15N-HMBC and other NMR spectra. We assumed that th
Autor:
Alexey L. Kayushin, Julia A. Tokunova, Ilja V. Fateev, Alexandra O. Arnautova, Maria Ya. Berzina, Alexander S. Paramonov, Olga I. Lutonina, Elena V. Dorofeeva, Konstantin V. Antonov, Roman S. Esipov, Igor A. Mikhailopulo, Anatoly I. Miroshnikov, Irina D. Konstantinova
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 539 (2021)
During the preparative synthesis of 2-fluorocordycepin from 2-fluoroadenosine and 3′-deoxyinosine catalyzed by E. coli purine nucleoside phosphorylase, a slowdown of the reaction and decrease of yield down to 5% were encountered. An unknown nucleos
Externí odkaz:
https://doaj.org/article/87d96404467d4b1785d17ba5e85c74d5
Autor:
Ilja V. Fateev, Maria A. Kostromina, Yuliya A. Abramchik, Barbara Z. Eletskaya, Olga O. Mikheeva, Dmitry D. Lukoshin, Evgeniy A. Zayats, Maria Ya. Berzina, Elena V. Dorofeeva, Alexander S. Paramonov, Alexey L. Kayushin, Irina D. Konstantinova, Roman S. Esipov
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 586 (2021)
A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from Thermus thermophilus HB27 was obta
Externí odkaz:
https://doaj.org/article/a43c27fb55dd43729d7fda5f02bbbe74
Autor:
Maria Ya, Berzina, Barbara Z, Eletskaya, Alexei L, Kayushin, Elena V, Dorofeeva, Olga I, Lutonina, Ilya V, Fateev, Alexander S, Paramonov, Maria A, Kostromina, Evgeniy A, Zayats, Yulia A, Abramchik, Dmitriy V, Maltsev, Ludmila V, Naumenko, Alena S, Taran, Dmitry S, Yakovlev, Alexander A, Spasov, Anatoly I, Miroshnikov, Roman S, Esipov, Irina D, Konstantinova
Publikováno v:
Bioorganic chemistry. 126
A series of purine ribonucleosides bearing chiral amino acid amides at the C6 position of 2-chloropurine was synthesized. Molecular docking of the synthesized analogs of 2-chloroadenosine by their affinity for A
Autor:
Elena V Dorofeeva, Alexander S. Paramonov, Y.A. Abramchik, Dmitry D Lukoshin, Irina D. Konstantinova, Barbara Z. Eletskaya, Roman S. Esipov, Evgeniy A Zayats, Maria Ya Berzina, M. A. Kostromina, Olga O Mikheeva, Alexey L Kayushin, Ilja V. Fateev
Publikováno v:
Biomolecules, Vol 11, Iss 586, p 586 (2021)
Biomolecules
Volume 11
Issue 4
Biomolecules
Volume 11
Issue 4
A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from Thermus thermophilus HB27 was obta
Autor:
Olga I. Lutonina, Konstantin V. Antonov, Ilja V. Fateev, Julia A Tokunova, Alexander S. Paramonov, Igor A. Mikhailopulo, Elena V Dorofeeva, Roman S. Esipov, Irina D. Konstantinova, Alexey L Kayushin, Alexandra O Arnautova, Anatoly I. Miroshnikov, Maria Ya Berzina
Publikováno v:
Biomolecules
Volume 11
Issue 4
Biomolecules, Vol 11, Iss 539, p 539 (2021)
Volume 11
Issue 4
Biomolecules, Vol 11, Iss 539, p 539 (2021)
During the preparative synthesis of 2-fluorocordycepin from 2-fluoroadenosine and 3′-deoxyinosine catalyzed by E. coli purine nucleoside phosphorylase, a slowdown of the reaction and decrease of yield down to 5% were encountered. An unknown nucleos
Autor:
Elena V Dorofeeva, Alexey L Kayushin, Irina D. Konstantinova, Olga I. Lutonina, Yulia A. Tokunova, Ilja V. Fateev, Vladimir N. Leonov, Roman S. Esipov, Anatoly I. Miroshnikov, Alexandra O. Denisova, Inessa S. Muzyka, Alexandra A. Breslav, Vladimir A. Stepchenko, Igor A. Mikhailopulo
Publikováno v:
Synthesis. 49:4853-4860
Two approaches to the chemoenzymatic synthesis of 2-fluorocordycepin and 2-chlorocordycepin were studied: (i) the use of 3′-deoxyadenosine (cordycepin) and 3′-deoxyinosine (3′dIno) as donors of 3-deoxy-d-ribofuranose in the transglycosylation o
Publikováno v:
Russian Journal of Bioorganic Chemistry. 35:193-196
The preparative method for the synthesis of 2-fluoroadenosine starting from commercially available guanosine was developed. It included the intermediate formation of 2-amino-6-azido-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)purine, which was isolate