Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elena Tsisanova"'
Autor:
N. Zaman, S.L.M. Walker, Keat-Eng Ng, Joseph Westaby, G. Mastroianni, Ryan C. Pink, S. Murtough, Paul J. Delaney, D. Thenet, Elena Tsisanova, Daniel J. Pennington, C.M. Webb, Andrew Tinker, David P. Kelsell
Publikováno v:
Cell and Tissue Research
The study of a desmoglein 2 murine model of arrhythmogenic cardiomyopathy revealed cardiac inflammation as a key early event leading to fibrosis. Arrhythmogenic cardiomyopathy (AC) is an inherited heart muscle disorder leading to ventricular arrhythm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac543c2bf4bb7d609238d5df700e92a
https://openaccess.sgul.ac.uk/id/eprint/113449/35/Ng2021_Article_EarlyInflammationPrecedesCardi.pdf
https://openaccess.sgul.ac.uk/id/eprint/113449/35/Ng2021_Article_EarlyInflammationPrecedesCardi.pdf
Autor:
Andreas Ludwig, Muriel Nobles, Sonia Sebastian, Patricia B. Munroe, Andrew Tinker, Elena Tsisanova
Publikováno v:
Physiological genomics. 53(4)
We have assessed the role of ric-b8 in the control of heart rate after the gene was implicated in a recent genome-wide association study of resting heart rate. We developed a novel murine model in which it was possible to conditionally delete ric-8b
Autor:
C.M. Webb, S.L.M. Walker, Andrew Tinker, Delphine Thenet, Joseph Westaby, Daniel J. Pennington, Paul J. Delaney, Ryan C. Pink, S. Murtough, Keat-Eng Ng, Elena Tsisanova, David P. Kelsell
The study of a desmoglein 2 murine model of arrhythmogenic cardiomyopathy revealed cardiac inflammation as a key early event leading to fibrosis. Arrhythmogenic Cardiomyopathy (AC) is an inherited heart muscle disorder leading to ventricular arrhythm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a934878af0225b7eee5fccfa6a9d0f2
https://doi.org/10.1101/2020.06.24.169664
https://doi.org/10.1101/2020.06.24.169664
Publikováno v:
Journal of Biological Chemistry. 292:17587-17597
ATP-sensitive potassium (KATP) channels are widely expressed in the cardiovascular system, where they regulate a range of biological activities by linking cellular metabolism with membrane excitability. KATP channels in vascular smooth muscle have a
Autor:
Elena Tsisanova, Javier Llorente, Janet Lowe, Eamonn Kelly, Graeme Henderson, Christopher P Bailey, Helen S Sanderson
Publikováno v:
The European Journal of Neuroscience
There is considerable controversy over whether μ-opioid receptor (MOPr) desensitization is homologous or heterologous and over the mechanisms underlying such desensitization. In different cell types MOPr desensitization has been reported to involve
Autor:
Mehrnoosh Ostovar, Janet Lowe, Sarah L. Withey, Christopher P Bailey, Alexandra E Cooke, Elena Tsisanova, Charles Chavkin, Helen S Sanderson, Eamonn Kelly, Stephen M. Husbands, Graeme Henderson
Publikováno v:
Lowe, J D, Sanderson, H S, Cooke, A E, Ostovar, M, Tsisanova, E, Withey, S L, Chavkin, C, Husbands, S M, Kelly, E, Henderson, G & Bailey, C P 2015, ' Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization ', Molecular Pharmacology, vol. 88, no. 2, pp. 347-356 . https://doi.org/10.1124/mol.115.098293
There is ongoing debate about the role of G protein-coupled receptor kinases (GRKs) in agonist-induced desensitization of the μ-opioid receptor (MOPr) in brain neurons. In the present paper, we have used a novel membrane-permeable, small-molecule in