Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elena Tripel"'
Autor:
Joerg Fellenberg, Sarina Losch, Marcela Arango-Ospina, Nina Hildenbrand, Elena Tripel, Lingyun Deng, Tobias Renkawitz, Fabian Westhauser, Burkhard Lehner, Aldo R. Boccaccini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10830 (2024)
Despite advances in treatment modalities, bone tumour therapies still face significant challenges. Severe side effects of conventional approaches, such as chemo- and radiation therapy, result in poor survival rates and high tumour recurrence rates, w
Externí odkaz:
https://doaj.org/article/6169c8f346274b349f280819691032fc
Autor:
Hadrian Platzer, Max Marinescu, Qaisar Nawaz, Elena Tripel, Simone Gantz, Axel Horsch, Volker Daniel, Aldo R. Boccaccini, Sébastien Hagmann, Babak Moradi, Tobias Renkawitz, Fabian Westhauser
Publikováno v:
Materials, Vol 16, Iss 24, p 7594 (2023)
Synovial inflammation in osteoarthritis (OA) is characterized by the release of cartilage-degrading enzymes and inflammatory cytokines. 45S5-bioactive glass (45S5-BG) can modulate inflammation processes; however, its influence on OA-associated inflam
Externí odkaz:
https://doaj.org/article/5a71c87c69ef4923b42acfaad317f5e7
Publikováno v:
Cells, Vol 13, Iss 1, p 61 (2023)
Although urgently needed, no significant improvements in osteosarcoma (OS) therapy have been achieved within the last decades. Here, we present a new therapeutic approach based on drug combinations consisting of mitochondrial complex I (MCI) inhibito
Externí odkaz:
https://doaj.org/article/1fd864f7f9d142de9e0f254c690d54c3
Autor:
Nils Rosshirt, Richard Trauth, Hadrian Platzer, Elena Tripel, Timo A. Nees, Hanns-Martin Lorenz, Theresa Tretter, Babak Moradi
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Investigating the pathophysiological mechanisms of early osteoarthritis (OA) is of utmost interest since this stage holds the strongest promise for therapeutic interventions. The aims of this study were to analyze if synovial infl
Externí odkaz:
https://doaj.org/article/c40748faf6eb4c7c853a781f07e4d1e6
Autor:
Timo Albert Nees, Jiji Alexander Zhang, Hadrian Platzer, Tilman Walker, Tobias Reiner, Elena Tripel, Babak Moradi, Nils Rosshirt
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2111 (2022)
Emerging evidence indicates that regulatory T cells (Treg) intervene in the inflammatory processes that drive osteoarthritis (OA). However, whether polarized Tregs affect clinical features of the disease in the short- or long-term, and if so, what th
Externí odkaz:
https://doaj.org/article/a0ecfeeefb7c43e09ab19d25b4bcca82
Autor:
Hadrian, Platzer, Richard, Trauth, Timo A, Nees, Elena, Tripel, Simone, Gantz, Marcus, Schiltenwolf, Babak, Moradi, Nils, Rosshirt
Publikováno v:
Journal of clinical medicine. 11(10)
Osteoarthritis (OA) is no longer considered a purely degenerative disease. OA is defined as a disease of the entire joint, in which inflammation occurs in various joint tissues. The overall aim of this study was to analyze the presence and polarizati
CD8+ T Cells in OA Knee Joints Are Differentiated into Subsets Depending on OA Stage and Compartment
Autor:
Hadrian Platzer, Richard Trauth, Timo A. Nees, Elena Tripel, Simone Gantz, Marcus Schiltenwolf, Babak Moradi, Nils Rosshirt
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2814
Osteoarthritis (OA) is no longer considered a purely degenerative disease. OA is defined as a disease of the entire joint, in which inflammation occurs in various joint tissues. The overall aim of this study was to analyze the presence and polarizati
Autor:
Christian Merle, Hester Haubenreisser, Babak Moradi, Tobias Reiner, Timo A Nees, Reza Sorbi, Tobias Gotterbarm, Elena Tripel, Nils Rosshirt, Sébastien Hagmann
Publikováno v:
Journal of Clinical Medicine
Volume 9
Issue 9
Journal of Clinical Medicine, Vol 9, Iss 2877, p 2877 (2020)
Volume 9
Issue 9
Journal of Clinical Medicine, Vol 9, Iss 2877, p 2877 (2020)
(1) Background: The objective of the present study was to investigate peripheral blood lymphocyte subpopulations in patients with small diameter metal-on-metal total hip arthroplasty (MoM THA) and elevated blood metal ion concentrations at long-term
Autor:
Timo A Nees, Nils Rosshirt, Hadrian Platzer, Simone Gantz, Babak Moradi, Sébastien Hagmann, Elena Tripel, Tobias Reiner
Publikováno v:
Journal of Clinical Medicine
Volume 9
Issue 5
Journal of Clinical Medicine, Vol 9, Iss 1279, p 1279 (2020)
Volume 9
Issue 5
Journal of Clinical Medicine, Vol 9, Iss 1279, p 1279 (2020)
Progressive loss of joint function in osteoarthritis (OA) is driven by degenerative and inflammatory processes and their complex interaction. Decoding the link between degeneration and inflammation is one of the most exciting approaches in understand
Autor:
Tobias Reiner, Theresa Tretter, Hanns-Martin Lorenz, Babak Moradi, Tilman Walker, Jiji Alexander Zhang, Nils Rosshirt, Elena Tripel, Timo A Nees, Hadrian Platzer, Marcus Schiltenwolf, Reza Sorbi, Sébastien Hagmann
Publikováno v:
Journal of Clinical Medicine
Volume 9
Issue 8
Journal of Clinical Medicine, Vol 9, Iss 2423, p 2423 (2020)
Volume 9
Issue 8
Journal of Clinical Medicine, Vol 9, Iss 2423, p 2423 (2020)
Despite the growing body of literature demonstrating a crucial role of T helper cell (Th) responses in the pathogenesis of osteoarthritis (OA), only few clinical studies have assessed interactions between Th cells and OA&mdash
related symptoms.
related symptoms.