Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elena Trepakova"'
Autor:
Frederick Sannajust, Bharathi Balasubramanian, Yeva Prysiazhniuk, Isha Verma, Elena Trepakova, Vaclav Belak
Publikováno v:
Toxicology Reports, Vol 6, Iss, Pp 305-320 (2019)
Toxicology Reports
Toxicology Reports
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are widely used for drug safety and efficacy testing with various techniques, including high content imaging (HCI). Upon drug treatment, a significant number of hiPSC-CMs grown in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c59c55b0624ecb81c23a47fc42371c2
http://www.sciencedirect.com/science/article/pii/S2214750018306279
http://www.sciencedirect.com/science/article/pii/S2214750018306279
The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model
Autor:
Jeffrey Travis, Chao-Min Hoe, Joseph J. Salata, Gloria J. Zingaro, Matthew M. Zrada, Pamela Gerenser, Armando Lagrutta, John Imredy, Elena Trepakova, Alysia A. Chaves, Greg Friedrichs, Masahiro Nishida, Kimberly M. Hoagland, Pierre Morissette
Publikováno v:
Journal of pharmacological and toxicological methods. 68(1)
Introduction In recent years, the anesthetized guinea pig has been used increasingly to evaluate the cardiovascular effects of drug-candidate molecules during lead optimization prior to conducting longer, more resource intensive safety pharmacology a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7569c48d2bd153328a78b217dbd0f5d
https://pubmed.ncbi.nlm.nih.gov/23649000
https://pubmed.ncbi.nlm.nih.gov/23649000
Autor:
Masahiro Nishida, Pamela Gerenser, Jeffrey Travis, Joseph J. Salata, Pierre Morissette, Kimberly M. Hoagland, Elena Trepakova, Gregory Friedrichs, Gloria J. Zingaro, Alysia A. Chaves
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e12-e13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad18ff0ee11bf4f25d1b525477e99ecc
https://doi.org/10.1016/j.vascn.2013.01.054
https://doi.org/10.1016/j.vascn.2013.01.054