Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elena Trepakova"'
Autor:
Frederick Sannajust, Bharathi Balasubramanian, Yeva Prysiazhniuk, Isha Verma, Elena Trepakova, Vaclav Belak
Publikováno v:
Toxicology Reports, Vol 6, Iss, Pp 305-320 (2019)
Toxicology Reports
Toxicology Reports
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are widely used for drug safety and efficacy testing with various techniques, including high content imaging (HCI). Upon drug treatment, a significant number of hiPSC-CMs grown in
The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model
Autor:
Jeffrey Travis, Chao-Min Hoe, Joseph J. Salata, Gloria J. Zingaro, Matthew M. Zrada, Pamela Gerenser, Armando Lagrutta, John Imredy, Elena Trepakova, Alysia A. Chaves, Greg Friedrichs, Masahiro Nishida, Kimberly M. Hoagland, Pierre Morissette
Publikováno v:
Journal of pharmacological and toxicological methods. 68(1)
Introduction In recent years, the anesthetized guinea pig has been used increasingly to evaluate the cardiovascular effects of drug-candidate molecules during lead optimization prior to conducting longer, more resource intensive safety pharmacology a
Autor:
Masahiro Nishida, Pamela Gerenser, Jeffrey Travis, Joseph J. Salata, Pierre Morissette, Kimberly M. Hoagland, Elena Trepakova, Gregory Friedrichs, Gloria J. Zingaro, Alysia A. Chaves
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e12-e13
Publikováno v:
Toxicological Sciences; Feb2019, Vol. 167 Issue 2, p573-580, 8p, 7 Graphs
Publikováno v:
Assay & Drug Development Technologies; Feb2015, Vol. 13 Issue 1, p55-55, 1p
Autor:
Zeng, Haoyu, Balasubramanian, Bharathi, Penniman, Jacob R., Kinose, Fumi, Salata, Joseph J., Lagrutta, Armando
Publikováno v:
Assay & Drug Development Technologies; Dec2013, Vol. 11 Issue 9/10, p544-550, 7p
Publikováno v:
Assay & Drug Development Technologies; Feb2016, Vol. 14 Issue 1, p67-67, 1p