Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elena Surova"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8698 (2024)
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease characterized by complement-mediated hemolysis and potentially life-threatening complications. Pegcetacoplan, an inhibitor of complement components C3 and C3b, was approved by the US Food an
Externí odkaz:
https://doaj.org/article/7aeeca49a9114374b7498a9799046901
Autor:
Valerio Renna, Elena Surova, Ahmad Khadour, Moumita Datta, Timm Amendt, Elias Hobeika, Hassan Jumaa
Publikováno v:
The Journal of Immunology
A considerable proportion of peripheral B cells is autoreactive, and it is unclear how the activation of such potentially harmful cells is regulated. In this study, we show that the different activation thresholds or IgM and IgD BCRs adjust B cell ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303c86919ccad25d5c6c3beb404da6b2
https://hdl.handle.net/21.11116/0000-000D-1D84-E21.11116/0000-000D-1D86-C
https://hdl.handle.net/21.11116/0000-000D-1D84-E21.11116/0000-000D-1D86-C
Autor:
Elena, Surova, Hassan, Jumaa
Publikováno v:
Advances in immunology. 123
The development and function of B lymphocytes critically depend on the non-germline B-cell antigen receptor (BCR). In addition to the diverse antigen-recognition regions, whose coding sequences are generated by the somatic DNA rearrangement, the vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4de6f3dbb622b611432fffe5879c7742
https://pubmed.ncbi.nlm.nih.gov/24840949
https://pubmed.ncbi.nlm.nih.gov/24840949
Autor:
Elena Surova, Hassan Jumaa
The development and function of B lymphocytes critically depend on the non-germline B-cell antigen receptor (BCR). In addition to the diverse antigen-recognition regions, whose coding sequences are generated by the somatic DNA rearrangement, the vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3e02cb2655cb0320f702a4e2f4eb767
https://doi.org/10.1016/b978-0-12-800266-7.00003-0
https://doi.org/10.1016/b978-0-12-800266-7.00003-0
Autor:
Daniel Hofmann, Marie Follo, Martina P. Bach, Elena Surova, Maike Buchner, Thomas Wossning, Rudolf Übelhart, Hedda Wardemann, Katja Zirlik, Hendrik Veelken, Marcus Dühren-von Minden, Hassan Jumaa, Fabian Kohler, Dunja Schneider
Publikováno v:
Nature, 489(7415), 309
B-cell receptor (BCR) signalling in chronic lymphocytic leukaemia (CLL) is found not to be dependent on exogenous antigens; instead, signalling may involve the binding of the BCR heavy-chain complementarity-determining region to self epitopes on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c327ad41a180e49d626e33882c99569a
https://pubmed.ncbi.nlm.nih.gov/22885698
https://pubmed.ncbi.nlm.nih.gov/22885698