Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elena Sopova"'
Autor:
Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Jonsson, Markus Ringnér, Linda Gillberg, Elena Sopova, Oleg Shupliakov, Camilla Koolmeister, Lars Olson, Thomas Perlmann, Nils-Göran Larsson
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009822 (2021)
Dopamine (DA) neurons of the midbrain are at risk to become affected by mitochondrial damage over time and mitochondrial defects have been frequently reported in Parkinson's disease (PD) patients. However, the causal contribution of adult-onset mitoc
Externí odkaz:
https://doaj.org/article/61f2fcf7bb484163bdda169112e41b0e
Autor:
Arndt Pechstein, Nikolay Tomilin, Kristin Fredrich, Olga Vorontsova, Elena Sopova, Emma Evergren, Volker Haucke, Lennart Brodin, Oleg Shupliakov
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2594-2602.e3 (2020)
Summary: Liquid-liquid phase separation is an increasingly recognized mechanism for compartmentalization in cells. Recent in vitro studies suggest that this organizational principle may apply to synaptic vesicle clusters. Here we test this possibilit
Externí odkaz:
https://doaj.org/article/6cc1614f910b4b439cda1a0b1b860adb
Autor:
Linda Gillberg, Viktor Jonsson, Camilla Koolmeister, Nils-Göran Larsson, Katarina Tiklova, Elena Sopova, Markus Ringnér, Oleg Shupliakov, Roberta Filograna, Lars Olson, Mara Mennuni, Thomas Perlmann, Seungmin Lee
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 9, p e1009822 (2021)
PLoS Genetics, Vol 17, Iss 9, p e1009822 (2021)
Dopamine (DA) neurons of the midbrain are at risk to become affected by mitochondrial damage over time and mitochondrial defects have been frequently reported in Parkinson’s disease (PD) patients. However, the causal contribution of adult-onset mit
Autor:
Moa Stenudd, Margherita Zamboni, Jonas Frisén, Joseph Bergenstråhle, Oleg Shupliakov, Marie Carlén, Yicheng Wu, Joakim Lundeberg, Pierre Le Merre, James M. Chell, Enric Llorens-Bobadilla, Elena Sopova
Publikováno v:
Science. 370
Spinal cord stem cells Injuries to the mammalian spinal cord do not heal easily. Llorens- Bobadilla et al. studied mouse ependymal cells, which function as stem cells for the spinal cord (see the Perspective by Becker and Becker). Chromatin accessibi
Publikováno v:
Biological Communications. 62:272-277
The midbrain dopaminergic neurons of the substantia nigra and the ventral tegmental area play vital roles in the regulation of voluntary movement, emotion and reward in humans. These neurons are highly metabolic and are under constant oxidative stres
Publikováno v:
European Neuropsychopharmacology. 40:S440-S441
Autor:
Tuomas Näreoja, Åsa M. E. Winther, Kathryn A. Rees, Olga Vorontsova, Wei Jiao, Oleg Shupliakov, Elena Sopova
Publikováno v:
The Journal of Neuroscience. 35:14756-14770
Many endocytic proteins accumulate in the reserve pool of synaptic vesicles (SVs) in synapses and relocalize to the endocytic periactive zone during neurotransmitter release. Currently little is known about their functions outside the periactive zone
Autor:
Elena Sopova, Oleg Shupliakov
Publikováno v:
European Neuropsychopharmacology. 29:S264
Autor:
Jochen Walter, Daniel N. Mitroi, Oleg Shupliakov, Dieter Swandulla, Gerhild van Echten-Deckert, André U. Deutschmann, Indulekha Karunakaran, Dan Ehninger, Konstantine Glebov, Michael Hans, Markus H. Gräler, Maren Raucamp, Julie D. Saba, Elena Sopova
Publikováno v:
Scientific Reports
Scientific reports 6(1), 37064 (2016). doi:10.1038/srep37064
Scientific reports 6(1), 37064 (2016). doi:10.1038/srep37064
The bioactive lipid sphingosine 1-phosphate (S1P) is a degradation product of sphingolipids that are particularly abundant in neurons. We have shown previously that neuronal S1P accumulation is toxic leading to ER-stress and an increase in intracellu