Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elena Soddu"'
Autor:
Paolo Giunchedi, Alessandro Dalpiaz, Massimo Cossu, Elena Soddu, Elisabetta Gavini, Giovanna Rassu
Publikováno v:
Journal of Drug Delivery Science and Technology. 32:77-87
The treatment of central nervous system diseases is very difficult due to the inability of drugs to permeate into the brain from the bloodstream. The intranasal route of administration allows for rapid drug delivery directly from the nasal mucosa to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062341a5a5a5092e16806c797f857d94
https://doi.org/10.1016/j.jddst.2015.05.002
https://doi.org/10.1016/j.jddst.2015.05.002
Publikováno v:
European Journal of Pharmaceutical Sciences. 74:63-76
Central nervous system (CNS) diseases are hard to diagnose and therapeutically target due to the blood brain barrier (BBB), which prevents most drugs from reaching their sites of action within the CNS. Brain drug delivery systems were conceived to by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64aa84029fcfd14924d25ffc6c55b11d
https://doi.org/10.1016/j.ejps.2015.04.005
https://doi.org/10.1016/j.ejps.2015.04.005
Publikováno v:
Pharmaceutical Development and Technology. 21:98-107
Cocoa butter (CB) is a largely used excipient in pharmaceutical field. Aim of this work was to set formulative parameters for the preparation of SLN based on "green" lipid matrix for drug delivery as natural, both human and environmental safe systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adfb66155c053e1a8f791618ff5ba6e
https://doi.org/10.3109/10837450.2014.971376
https://doi.org/10.3109/10837450.2014.971376
Autor:
Elena Soddu, Elisabetta Gavini, Bruno Sarmento, Anna Maria Posadino, Paolo Giunchedi, Giovanna Rassu, Gianfranco Pintus
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 152
We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell-penetrating peptide, the short peptide derived from rabies virus g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ca994a3861be38d6d2bd6e83f261dc
https://pubmed.ncbi.nlm.nih.gov/28126681
https://pubmed.ncbi.nlm.nih.gov/28126681
Autor:
Guliz Armagan, Elena Soddu, Lutfiye Kanit, Paolo Giunchedi, Giovanna Rassu, Yiğit Uyanıkgil, Ayfer Yalcin, Ezgi Turunc Bayrakdar, Elisabetta Gavini
Publikováno v:
Journal of pharmaceutical sciences. 105(8)
β-Amyloid (Aβ) plaques are the key neurotoxic assemblies in Alzheimer disease. It has been suggested that an interaction occurs between membrane cholesterol and Aβ aggregation in the brain. Cyclodextrins can remove cholesterol from cell membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d635215ac862cdf5dead9781a538315a
https://pubmed.ncbi.nlm.nih.gov/27353207
https://pubmed.ncbi.nlm.nih.gov/27353207