Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Elena Shekhova"'
Autor:
Elena Shekhova, Fabián Salazar, Alessandra Da Silva Dantas, Tanmoy Chakraborty, Eva L. Wooding, P. Lewis White, Adilia Warris
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Invasive Aspergillosis (IA) is a life-threatening fungal disease with significant mortality rates. Timely diagnosis and treatment greatly enhance patient outcomes. This study aimed to explore the association between patient age an
Externí odkaz:
https://doaj.org/article/59328aef5279436ab6cb3e7fc6795c1f
Autor:
Arnab Pradhan, Gabriela M. Avelar, Judith M. Bain, Delma Childers, Chloe Pelletier, Daniel E. Larcombe, Elena Shekhova, Mihai G. Netea, Gordon D. Brown, Lars Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern.
Externí odkaz:
https://doaj.org/article/bd3459245a7f49d29f8307da698409ae
Autor:
Phuong Tuyen Nguyen, Theresa Wacker, Alistair J. P. Brown, Alessandra da Silva Dantas, Elena Shekhova
Publikováno v:
Journal of Fungi, Vol 8, Iss 7, p 736 (2022)
Aspergillus fumigatus is the leading cause of the fungal invasive disease called aspergillosis, which is associated with a high mortality rate that can reach 50% in some groups of immunocompromised individuals. The increasing prevalence of azole-resi
Externí odkaz:
https://doaj.org/article/fd84e0541cf64000951af11a2dae62e2
Autor:
Remi Hatinguais, Arnab Pradhan, Gordon D. Brown, Alistair J. P. Brown, Adilia Warris, Elena Shekhova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Reactive Oxygen Species (ROS) are highly reactive molecules that can induce oxidative stress. For instance, the oxidative burst of immune cells is well known for its ability to inhibit the growth of invading pathogens. However, ROS also mediate redox
Externí odkaz:
https://doaj.org/article/d58d2f5f277b4a969e55066468b76c61
Autor:
Elena Shekhova
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008470 (2020)
Externí odkaz:
https://doaj.org/article/b52793d4685e4402ab0aa999c2427690
Autor:
Arnab Pradhan, Gabriela M. Avelar, Judith M. Bain, Delma S. Childers, Daniel E. Larcombe, Mihai G. Netea, Elena Shekhova, Carol A. Munro, Gordon D. Brown, Lars P. Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Organisms must adapt to changes in oxygen tension if they are to exploit the energetic benefits of reducing oxygen while minimizing the potentially damaging effects of oxidation. Consequently, organisms in all eukaryotic kingdoms display rob
Externí odkaz:
https://doaj.org/article/7246d978081d4c2eaaefcf2803e7a1d6
Autor:
Alistair J. P. Brown, Gordon D. Brown, Remi Hatinguais, Adilia Warris, Arnab Pradhan, Elena Shekhova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Reactive Oxygen Species (ROS) are highly reactive molecules that can induce oxidative stress. For instance, the oxidative burst of immune cells is well known for its ability to inhibit the growth of invading pathogens. However, ROS also mediate redox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9d5c84fe50b362b478d63dec94c238
https://doi.org/10.3389/fimmu.2021.641495
https://doi.org/10.3389/fimmu.2021.641495
Autor:
Elena Shekhova, Gabriela Mol Avelar, Daniel E. Larcombe, Judith M. Bain, Neil A. R. Gow, Gordon D. Brown, Mihai G. Netea, Lars Erwig, Chloe Pelletier, Delma S. Childers, Arnab Pradhan, Alistair J. P. Brown
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 10
To colonise their host, pathogens must counter local environmental and immunological challenges. Here, we reveal that the fungal pathogen Candida albicans exploits diverse host-associated signals to promote immune evasion by masking of a major pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc3767c7a701811f058c3d41cfb98dc
http://europepmc.org/articles/PMC6876565
http://europepmc.org/articles/PMC6876565
Autor:
Axel A. Brakhage, Kristin Kroll, Maria Strassburger, Ekaterina Shelest, Andreas Thywissen, Derek J. Mattern, Olaf Kniemeyer, Ilse D. Jacobsen, Elena Shekhova, Thorsten Heinekamp
Publikováno v:
Molecular Microbiology. 101:92-108
Aspergillus fumigatus is the predominant airborne pathogenic fungus causing invasive aspergillosis in immunocompromised patients. During infection A. fumigatus has to adapt to oxygen-limiting conditions in inflammatory or necrotic tissue. Previously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3894d64514ef66448e7e30e121002921
https://doi.org/10.1111/mmi.13377
https://doi.org/10.1111/mmi.13377
Autor:
Mihai G. Netea, Daniel E. Larcombe, Judith M. Bain, Lars P. Erwig, Carol A. Munro, Elena Shekhova, Gabriela Mol Avelar, Arnab Pradhan, Gordon D. Brown, Neil A. R. Gow, Delma S. Childers, Alistair J. P. Brown
Publikováno v:
Mbio, 9, e01318-18
Mbio, 9, 6, pp. e01318-18
mBio, Vol 9, Iss 6 (2018)
mBio
mBio, Vol 9, Iss 6, p e01318-18 (2018)
Mbio, 9, 6, pp. e01318-18
mBio, Vol 9, Iss 6 (2018)
mBio
mBio, Vol 9, Iss 6, p e01318-18 (2018)
Animal, plant, and fungal cells occupy environments that impose changes in oxygen tension. Consequently, many species have evolved mechanisms that permit robust adaptation to these changes. The fungal pathogen Candida albicans can colonize hypoxic (l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bd3a15754d74cfe2536857f40a7041
http://hdl.handle.net/2066/200161
http://hdl.handle.net/2066/200161
