Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elena Senís"'
Autor:
Elena Senís, Miriam Esgleas, Sonia Najas, Verónica Jiménez-Sábado, Camilla Bertani, Marta Giménez-Alejandre, Alba Escriche, Jorge Ruiz-Orera, Marta Hergueta-Redondo, Mireia Jiménez, Albert Giralt, Paolo Nuciforo, M. Mar Albà, Héctor Peinado, Daniel del Toro, Leif Hove-Madsen, Magdalena Götz, María Abad
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Long noncoding RNAs (lncRNAs) are regulatory molecules which have been traditionally considered as “non-coding”. Strikingly, recent evidence has demonstrated that many non-coding regions, including lncRNAs, do in fact contain small-open reading f
Externí odkaz:
https://doaj.org/article/3dac13a368e84670974c18ed67fa60c7
Autor:
Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano, Dirk Grimm
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.
Externí odkaz:
https://doaj.org/article/097051282c3e433e8f3bfa8162e92d23
Autor:
Steeve Boulant, Kalliopi Pervolaraki, Megan L. Stanifer, Stephanie Münchau, Lynnsey A. Renn, Dorothee Albrecht, Stefan Kurzhals, Elena Senís, Dirk Grimm, Jutta Schröder-Braunstein, Ronald L. Rabin
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Intestinal epithelial cells (IECs) are constantly exposed to commensal flora and pathogen challenges. How IECs regulate their innate immune response to maintain gut homeostasis remains unclear. Interferons (IFNs) are cytokines produced during infecti
Externí odkaz:
https://doaj.org/article/c09051b10bf043ab800d38ec04272a5a
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2318
Cellular reprogramming is a process by which adult differentiated cells lose their identity and are converted into pluripotent stem cells, known as induced pluripotent stem (iPS) cells. This process can be achieved in vitro and in vivo and is relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3db47bd52b043c1d6f22e088db1b4249
https://pubmed.ncbi.nlm.nih.gov/34019296
https://pubmed.ncbi.nlm.nih.gov/34019296
Publikováno v:
The Myc Gene ISBN: 9781071614754
Cellular reprogramming is a process by which adult differentiated cells lose their identity and are converted into pluripotent stem cells, known as induced pluripotent stem (iPS) cells. This process can be achieved in vitro and in vivo and is relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b184d635b72b297a7770baba7c99f988
https://doi.org/10.1007/978-1-0716-1476-1_14
https://doi.org/10.1007/978-1-0716-1476-1_14
Autor:
Megan L. Stanifer, Dorothee Albrecht, Ronald L. Rabin, Elena Senís, Lynnsey A. Renn, Steeve Boulant, Kalliopi Pervolaraki, Stephanie Margarete Münchau, Dirk Grimm, Jutta Schröder-Braunstein, Stefan Kurzhals
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, Vol 8 (2017)
Intestinal epithelial cells (IECs) are constantly exposed to commensal flora and pathogen challenges. How IECs regulate their innate immune response to maintain gut homeostasis remains unclear. Interferons (IFNs) are cytokines produced during infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9033d4bf318f5dc10cf988b528ef0cd8
https://doi.org/10.3389/fimmu.2017.00459
https://doi.org/10.3389/fimmu.2017.00459
Autor:
Wilson Pak-Kin Lou, Ana Martin-Villalba, Carlos Maillo, Marta Koch, Raúl Méndez, Stefanie Limpert, Manuel Göpferich, Na Lu, Alvaro Mateos, Bassem A. Hassan, Kai Liu, Marlen Zschaetzsch, Chao Yang, Stefan Klussman, Dirk Grimm, Elena Senís
Adult mammalian CNS neurons are unable to regenerate following axonal injury, leading to permanent functional impairments. Yet, the reasons underlying this regeneration failure are not fully understood. Here, we study the transcriptome and proteome s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a14b805aa8f4ce308fb9938e20b3343
https://doi.org/10.1101/125096
https://doi.org/10.1101/125096
Publikováno v:
Molecular Therapy. 23
The 2006/7 discovery that somatic cells of different tissue origins can be converted into induced pluripotent stem cells (iPSC) by mere introduction of a cocktail of “reprogramming” factors, such as Oct4, Klf4, Sox2 and c-Myc (OKSM), has revoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9dac137c0d9164748c72be46f3eca3
Autor:
Ellen Wiedtke, Kathleen Börner, Ann-Kristin Mueller, Dominik Niopek, Dirk Grimm, Stefanie Große, Elena Senís, Chronis Fatouros
Publikováno v:
Biotechnology journal. 9(11)
Its remarkable ease and efficiency make the CRISPR (clustered regularly interspaced short palindromic repeats) DNA editing machinery highly attractive as a new tool for experimental gene annotation and therapeutic genome engineering in eukaryotes. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa1c1d716cddc2b38042ebb86deac59
https://pubmed.ncbi.nlm.nih.gov/25186301
https://pubmed.ncbi.nlm.nih.gov/25186301
Autor:
Fabian J. Theis, Elena Senís, Peter Lichter, Jan Gronych, Dirk Grimm, Roland Eils, Ralf Bartenschlager, Nagarajan Paramasivam, Florian Schmidt, Bettina Knapp, Daniel Rupp, Stefanie Grosse, Stefan Mockenhaupt, Tobias Bauer, Matthias Schlesner, Marc P. Windisch
Publikováno v:
Europe PubMed Central
Nucleic Acids Research
Nucleic Acids Res. 45:e3 (2017)
Nucleic Acids Research
Nucleic Acids Res. 45:e3 (2017)
Successful RNAi applications depend on strategies allowing robust and persistent expression of minimal gene silencing triggers without perturbing endogenous gene expression. Here, we propose a novel avenue which is integration of a promoterless shmiR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6ae1bfa2150944df671babec8216b9
https://doi.org/10.1093/nar/gkw805
https://doi.org/10.1093/nar/gkw805