Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elena S. Wall"'
Autor:
Joanne Shu Ming Chia, Elena S. Wall, Caroline Lei Wee, Thomas A. J. Rowland, Ruey-Kuang Cheng, Kathleen Cheow, Karen Guillemin, Suresh Jesuthasan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
When injured, fish release an alarm substance produced by club cells in the skin that elicits fear in members of their shoal. Here, the authors show that mucus and bacteria are transported from the external surface into club cells, and bacterial comp
Externí odkaz:
https://doaj.org/article/9038497db4804db6ad4a1ac3a72ce23c
Autor:
Travis J. Wiles, Elena S. Wall, Brandon H. Schlomann, Edouard A. Hay, Raghuveer Parthasarathy, Karen Guillemin
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Correlating the presence of bacteria and the genes they carry with aspects of plant and animal biology is rapidly outpacing the functional characterization of naturally occurring symbioses. A major barrier to mechanistic studies is the lack
Externí odkaz:
https://doaj.org/article/6d927dab039044e9a29cca5aab4fbc96
Autor:
Travis J Wiles, Brandon H Schlomann, Elena S Wall, Reina Betancourt, Raghuveer Parthasarathy, Karen Guillemin
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000661 (2020)
Some of the densest microbial ecosystems in nature thrive within the intestines of humans and other animals. To protect mucosal tissues and maintain immune tolerance, animal hosts actively sequester bacteria within the intestinal lumen. In response,
Externí odkaz:
https://doaj.org/article/ddda8be598eb4b36b533413120d9e6f4
Autor:
Keaton Stagaman, Sophie R. Sichel, Thomas J. Sharpton, Karen Guillemin, Virginia Watral, Michael L. Kent, Elena S. Wall
Publikováno v:
Zebrafish
Intestinal neoplasms and preneoplastic lesions are common in zebrafish research facilities. Previous studies have demonstrated that these neoplasms are caused by a transmissible agent, and two candidate agents have been implicated: a Mycoplasma sp. r
Autor:
Jennifer Hampton Hill, Michelle Sconce Massaquoi, Emily Goers Sweeney, Elena S. Wall, Philip Jahl, Rickesha Bell, Karen Kallio, Daniel Derrick, L. Charles Murtaugh, Raghuveer Parthasarathy, S. James Remington, June L. Round, Karen Guillemin
Publikováno v:
Cell metabolism. 34(11)
Microbiome dysbiosis is a feature of diabetes, but how microbial products influence insulin production is poorly understood. We report the mechanism of BefA, a microbiome-derived protein that increases proliferation of insulin-producing β cells duri
Autor:
Jennifer Hampton Hill, Michelle Sconce Massaquoi, Emily Goers Sweeney, Elena S. Wall, Philip Jahl, Rickesha Bell, Karen Kallio, Daniel Derrick, L. Charles Murtaugh, Raghuveer Parthasarathy, S. James Remington, June L. Round, Karen Guillemin
SummaryMicrobiome dysbiosis is a feature of diabetes, but how microbial products influence insulin production is poorly understood. Here we report the mechanism of BefA, a microbiome-derived protein that increases proliferation of insulin-producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c6da47b1e4d4675063b86e4238a445
https://doi.org/10.1101/2022.03.24.485696
https://doi.org/10.1101/2022.03.24.485696
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1009989 (2022)
The enteric nervous system (ENS) controls many aspects of intestinal homeostasis, including parameters that shape the habitat of microbial residents. Previously we showed that zebrafish lacking an ENS, due to deficiency of the sox10 gene, develop int
Autor:
Karen Guillemin, Travis J. Wiles, Brandon H. Schlomann, Reina Betancourt, Elena S. Wall, Raghuveer Parthasarathy
Publikováno v:
PLoS Biology
PLoS Biology, Vol 18, Iss 3, p e3000661 (2020)
PLoS Biology, Vol 18, Iss 3, p e3000661 (2020)
Some of the densest microbial ecosystems in nature thrive within the intestines of humans and other animals. To protect mucosal tissues and maintain immune tolerance, animal hosts actively sequester bacteria within the intestinal lumen. In response,
Autor:
Karen Guillemin, Raghuveer Parthasarathy, Travis J. Wiles, Elena S. Wall, Brandon H. Schlomann
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(43)
Antibiotics induce large and highly variable changes in the intestinal microbiome even at sublethal concentrations, through mechanisms that remain elusive. Using gnotobiotic zebrafish, which allow high-resolution examination of microbial dynamics, we
Autor:
Raghuveer Parthasarathy, Brandon H. Schlomann, Reina Betancourt, Karen Guillemin, Elena S. Wall, Travis J. Wiles
SUMMARYUnderstanding the processes that spatially restrict resident gut bacteria and the mechanisms by which disease-causing pathobionts escape this control will open new avenues for microbiome-based therapies. Using live imaging and genetically engi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a568d6fe05cf0b0d8e64d4a6d7e483
https://doi.org/10.1101/779983
https://doi.org/10.1101/779983