Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Elena Raimondi"'
Autor:
Angela La Grua, Ilaria Rao, Lucia Susani, Franco Lucchini, Elena Raimondi, Paolo Vezzoni, Marianna Paulis
Publikováno v:
Cells, Vol 13, Iss 8, p 666 (2024)
There are thousands of rare genetic diseases that could be treated with classical gene therapy strategies such as the addition of the defective gene via viral or non-viral delivery or by direct gene editing. However, several genetic defects are too c
Externí odkaz:
https://doaj.org/article/7ca2234b15674f8f999320e6f1362edb
Autor:
Lisa Zanoletti, Aurora Valdata, Kristina Nehlsen, Pawan Faris, Claudio Casali, Rosalia Cacciatore, Ilaria Sbarsi, Francesca Carriero, Davide Arfini, Lies van Baarle, Veronica De Simone, Giulia Barbieri, Elena Raimondi, Tobias May, Francesco Moccia, Mauro Bozzola, Gianluca Matteoli, Sergio Comincini, Federico Manai
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Enteric glial cells (EGCs), the major components of the enteric nervous system (ENS), are implicated in the maintenance of gut homeostasis, thereby leading to severe pathological conditions when impaired. However, due to technical difficulties associ
Externí odkaz:
https://doaj.org/article/46085daa87684a25bcbdff56101104a8
Autor:
Francesca M Piras, Solomon G Nergadze, Elisa Magnani, Livia Bertoni, Carmen Attolini, Lela Khoriauli, Elena Raimondi, Elena Giulotto
Publikováno v:
PLoS Genetics, Vol 6, Iss 2, p e1000845 (2010)
In a previous study, we showed that centromere repositioning, that is the shift along the chromosome of the centromeric function without DNA sequence rearrangement, has occurred frequently during the evolution of the genus Equus. In this work, the an
Externí odkaz:
https://doaj.org/article/69e0869427124ff2bae77ddf16e5d6c1
Autor:
Eleonora Cappelletti, Francesca M Piras, Lorenzo Sola, Marco Santagostino, Wasma A Abdelgadir, Elena Raimondi, Francesco Lescai, Solomon G Nergadze, Elena Giulotto
Publikováno v:
Molecular biology and evolution. 39(8)
Centromeres are epigenetically specified by the histone H3 variant CENP-A and typically associated with highly repetitive satellite DNA. We previously discovered natural satellite-free neocentromeres in Equus caballus and Equus asinus. Here, through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ecef86d35e35f9738cc7a2deb3891d
https://pubmed.ncbi.nlm.nih.gov/35881460
https://pubmed.ncbi.nlm.nih.gov/35881460
Autor:
Rebecca M. Harman, Marco Corbo, Francesco Gozzo, Solomon G. Nergadze, Federico Cerutti, Eleonora Cappelletti, Joseph G.W. McCarter, Riccardo Gamba, Maren Scharfe, Kevin F. Sullivan, Douglas F. Antczak, Elena Giulotto, Elena Raimondi, Donald Miller, Francesca M. Piras, Giulio Pavesi
Publikováno v:
Genome research
Mammalian centromeres are associated with highly repetitive DNA (satellite DNA), which has so far hindered molecular analysis of this chromatin domain. Centromeres are epigenetically specified, and binding of the CENPA protein is their main determina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badaa26914542764e1ab652c5d3c0ff4
https://doi.org/10.1101/gr.231159.117
https://doi.org/10.1101/gr.231159.117
Autor:
Mirella Bensi, Francesca M. Piras, Solomon G. Nergadze, Annalisa Roberti, Elena Giulotto, Alice Mazzagatti, Elena Raimondi
Publikováno v:
Genes, Vol 10, Iss 6, p 469 (2019)
Genes
Genes
The typical vertebrate centromeres contain long stretches of highly repeated DNA sequences (satellite DNA). We previously demonstrated that the karyotypes of the species belonging to the genus Equus are characterized by the presence of satellite-free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1066a9a4a1c35b7d9753d30b27b57ab1
https://www.mdpi.com/2073-4425/10/6/469
https://www.mdpi.com/2073-4425/10/6/469
Publikováno v:
Progress in molecular and subcellular biology. 56
Centromeres are highly distinctive genetic loci whose function is specified largely by epigenetic mechanisms. Understanding the role of DNA sequences in centromere function has been a daunting task due to the highly repetitive nature of centromeres i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5202d43afdf01bf7505e782a16dc2c17
https://pubmed.ncbi.nlm.nih.gov/28840244
https://pubmed.ncbi.nlm.nih.gov/28840244
Autor:
Federico Cerutti, Monica Zoli, Solomon G. Nergadze, Elena Giulotto, Kevin F. Sullivan, Giuliano Della Valle, Claudia Badiale, Giovanni Perini, Mariano Rocchi, Elisa Belloni, Francesca M. Piras, Stefania Purgato, Elena Raimondi, Alice Mazzagatti
Publikováno v:
Chromosoma
The centromere directs the segregation of chromosomes during mitosis and meiosis. It is a distinct genetic locus whose identity is established through epigenetic mechanisms that depend on the deposition of centromere-specific centromere protein A (CE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d55c7ab42ff3c71bcf915642abb2d94
http://europepmc.org/articles/PMC4446527
http://europepmc.org/articles/PMC4446527
Autor:
Elena Giulotto, Mirella Bensi, Lela Khoriauli, Francesca M. Piras, Valerio Vitelli, Solomon G. Nergadze, Elisa Belloni, Elena Raimondi, Francesco Vella, Alice Mazzagatti
Publikováno v:
Cytogenetic and Genome Research. 144:114-123
Centromeres are the sites of kinetochore assembly and spindle fiber attachment and consist of protein-DNA complexes in which the DNA component is typically characterized by the presence of extended arrays of tandem repeats called satellite DNA. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff393af0d452b82f283af3b6933cdb7
https://doi.org/10.1159/000368138
https://doi.org/10.1159/000368138
Publikováno v:
Plant Signaling & Behavior. 6:516-519
A wide range of pharmacological properties are ascribed to natural saponins, in addition to their biological activities against herbivores, plant soil-borne pathogens and pests. As for animal cells, the cytotoxicity and the chemopreventive role of sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ac6db721fbd6ebb213e42cba582d4b
https://doi.org/10.4161/psb.6.4.14746
https://doi.org/10.4161/psb.6.4.14746