Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Elena Pokidysheva"'
Autor:
Xiaolei Lian, J. Steffan Bond, Narendra Bharathy, Sergei P. Boudko, Elena Pokidysheva, Jack F. Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M. Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P. Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H. Gultekin, Noah E. Berlow, Charles Keller
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes conventional systemic chemotherapy, radiation therapy, and surgical resection; nevertheless,
Externí odkaz:
https://doaj.org/article/521d60c3b7d3445ea5dac9b82bf56121
Publikováno v:
Curr Opin Nephrol Hypertens
PURPOSE OF REVIEW: In Alport syndrome, over 1,700 genetic variants in the COL4A3, COL4A4, and COL4A5 genes cause the absence or malfunctioning of the collagen IV(α345) scaffold – an essential component of the glomerular basement membrane (GBM). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61660f5cc0516387381c47976bd8bde8
https://pubmed.ncbi.nlm.nih.gov/35283436
https://pubmed.ncbi.nlm.nih.gov/35283436
Autor:
Vadim Pedchenko, Alaa Al-Shaer, Billy G. Hudson, Ryan Bauer, Sergei P. Boudko, Elena Pokidysheva, Aaron L. Fidler, Nancy R. Forde
Publikováno v:
The Journal of Biological Chemistry
Collagen IV scaffold is a principal component of the basement membrane (BM), a specialized extracellular matrix that is essential for animal multicellularity and tissue evolution. Scaffold assembly begins with the trimerization of α-chains into prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda103204f1ed290babbb150a7ff6080
https://doi.org/10.1074/jbc.ra119.007426
https://doi.org/10.1074/jbc.ra119.007426
Autor:
Ayeza Bajwa, J Steffan Bond, Charles Keller, Sergei P. Boudko, Sakir H. Gultekin, Atiya Mansoor, Megan M. Cleary, Teagan P. Settelmeyer, Christopher P. Hartley, Noah E. Berlow, Melvin Lathara, Hans Peter Bächinger, Elena Pokidysheva, Takako Sasaki, Jack F. Shern, Narendra Bharathy, Xiaolei Lian, Ganapati Srinivasa
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes conventional systemic chemotherapy, radiation therapy, and surgical resection; nevertheless,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422209340e2ad410e025606fd7c5bebe
https://www.frontiersin.org/articles/10.3389/fonc.2021.601957/full
https://www.frontiersin.org/articles/10.3389/fonc.2021.601957/full
Autor:
Xiaolei Lian, J. Steffan Bond, Narendra Bharathy, Sergei P. Boudko, Elena Pokidysheva, Jack F. Shern, Melvin Lathara, Teagan Settelmeyer, Megan M. Cleary, Ayeza Bajwa, Ganapati Sriniv, Christopher P. Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H. Gultekin, Noah E. Berlow, Charles Keller
Background: Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes conventional systemic chemotherapy, radiation therapy and surgical resection; ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c21721704d90b19d5cec5d83960d007
https://doi.org/10.21203/rs.3.rs-38028/v1
https://doi.org/10.21203/rs.3.rs-38028/v1
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030678135
Collagen molecules are crucial extracellular players in animal tissue development and in functions ranging from ultrafiltration to organism locomotion. Among the 28 types of collagen found in human, type IV collagen stands out as a primordial type fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c18b2c06502b6e2b56dde419a7ddf1
https://doi.org/10.1007/5584_2020_582
https://doi.org/10.1007/5584_2020_582
Publikováno v:
Journal of Biological Chemistry. 293:5987-5999
Type IV collagen is a major component of the basement membrane and interacts with numerous other basement membrane proteins. Many of these interactions are poorly characterized. Type IV collagen is abundantly post-translationally modified with 3-hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608afedeec11c57d41d687170ef01f92
https://doi.org/10.1074/jbc.ra117.000406
https://doi.org/10.1074/jbc.ra117.000406
Autor:
George Haddad, Charles D. Pusey, Agnes B. Fogo, Dale R. Abrahamson, Rudolf P. Wüthrich, Clifford E. Kashtan, Alicia Simmons, Paul A. Voziyan, Fernando C. Fervenza, Sergei P. Boudko, Timo Wagner, Zhao Wei Cui, A. Richard Kitching, Raymond C. Harris, Eric Delpire, Andreas D. Kistler, Johan M. Lorenzen, Ming-Hui Zhao, Aaron L. Fidler, Sergei V. Chetyrkin, Ariana Gaspert, Carsten Bergmann, Oliver Gross, Billy G. Hudson, Maik Grohmann, Marten Segelmark, Harald Seeger, Elena Pokidysheva, Stephen P. McAdoo, Vadim Pedchenko
Publikováno v:
The Journal of Biological Chemistry
Diseases of the glomerular basement membrane (GBM), such as Goodpasture’s disease (GP) and Alport syndrome (AS), are a major cause of chronic kidney failure and an unmet medical need. Collagen IVα345 is an important architectural element of the GB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed717b2a810710cfdf2e9dee7466f10
https://doi.org/10.1016/j.jbc.2021.100590
https://doi.org/10.1016/j.jbc.2021.100590
Autor:
Markus Moser, Hans Peter Bächinger, Keith D. Zientek, Janice A. Vranka, Reinhard Fässler, Jerry Ware, Sergei P. Boudko, Elena Pokidysheva, Kerry Maddox
Publikováno v:
Proceedings of the National Academy of Sciences. 111:161-166
Collagens constitute nearly 30% of all proteins in our body. Type IV collagen is a major and crucial component of basement membranes. Collagen chains undergo several posttranslational modifications that are indispensable for proper collagen function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0387317b36afaa26a631252526557b7b
https://doi.org/10.1073/pnas.1307597111
https://doi.org/10.1073/pnas.1307597111
Autor:
Hans Peter Bächinger, Keith D. Zientek, Kazuhiro Nagata, Kazunori Mizuno, Ann M. Rashmir-Raven, Janice A. Vranka, Yoshihiro Ishikawa, Elena Pokidysheva, Nena J. Winand, Douglas R. Keene, Sergei P. Boudko
Publikováno v:
Journal of Biological Chemistry. 287:22253-22265
The rate-limiting step of folding of the collagen triple helix is catalyzed by cyclophilin B (CypB). The G6R mutation in cyclophilin B found in the American Quarter Horse leads to autosomal recessive hyperelastosis cutis, also known as hereditary equ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013c1561de76c458e1bfdf8f96e2cb11
https://doi.org/10.1074/jbc.m111.333336
https://doi.org/10.1074/jbc.m111.333336