Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elena Noe"'
Publikováno v:
Animals, Vol 10, Iss 5, p 857 (2020)
The use of animals in research requires careful ethical consideration of whether the burden on the animals is justified. As one important part of the project evaluation, a harm–benefit analysis (HBA) must be carried out in order to approve projects
Externí odkaz:
https://doaj.org/article/56f523527e904960b3df0aae4cc5289a
Autor:
Stephanie Krämer, Monika Reißmann, Boris Jerchow, Astrid Puppe, Kristina Ullmann, Thomas Rülicke, Elena Noe, Claudia Gosele, Anne Zintzsch, Hannah T. Nickles, Reinhart Kluge
Publikováno v:
Laboratory Animals. 51:573-582
Genetic alterations can unpredictably compromise the wellbeing of animals. Thus, more or less harmful phenotypes might appear in the animals used in research projects even when they are not subjected to experimental treatments. The severity classific
Autor:
Elena Noe, Christoph Tabeling, Robert Klopfleisch, Martin Witzenrath, Bastian Opitz, Jan Naujoks, JM Doehn, Stefan Hippenstiel
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 196:365-371
Megaesophagus in mice has been associated with several genetic defects. In the present study we expand the range of genes associated with esophageal function and morphology by protein kinase C alpha (PKCα). PKCα-deficient mice showed a six times in
Autor:
Birgitt Gutbier, H Yu, Elena Noe, Neil M. Goldenberg, Norbert Suttorp, Adrienn Krauszman, L Wang, Jun Yin, Christoph Tabeling, Wolfgang M. Kuebler, Martina Barbara Schaefer, Martin Witzenrath, Richard L. Proia, Christoph Arenz, Diana Zabini, Hannes Ranke, Andreas C. Hocke
Publikováno v:
Pneumologie. 70
Autor:
Hanpo Yu, Hannes Ranke, Liming Wang, Adrienn Krauszman, Wolfgang M. Kuebler, Andreas C. Hocke, Diana Zabini, Richard L. Proia, Birgitt Gutbier, Norbert Suttorp, Christoph Arenz, Christoph Tabeling, Neil M. Goldenberg, Elena Noe, Martin Witzenrath, Jun Yin, Michael Schaefer
Publikováno v:
4.3 Pulmonary Circulation and Pulmonary Vascular Disease.
Background: Gene mutations of cystic fibrosis transmembrane conductance regulator (CFTR) cause cystic fibrosis, which is associated with profound pulmonary ventilation-perfusion (V A /Q) mismatches. Hypoxic pulmonary vasoconstriction (HPV) minimizes
Autor:
Martin Witzenrath, Robert Klopfleisch, Elena Noe, Norbert Suttorp, Jan Naujoks, Bastian Opitz, Stefan Hippenstiel, Christoph Tabeling, JM Doehn
Publikováno v:
Journal of vascular research. 52(4)
Pulmonary vascular hyperresponsiveness is a main characteristic of pulmonary arterial hypertension (PAH). In PAH patients, elevated levels of the vasoconstrictors thromboxane A2 (TXA2), endothelin (ET)-1 and serotonin further contribute to pulmonary
Autor:
Wolfgang M. Kuebler, Elena Noe, Christoph Tabeling, Birgitt Gutbier, Norbert Suttorp, Neil M. Goldenberg, Martin Witzenrath, Michael Schaefer, Diana Zabini, Christoph Arenz, Adrienn Krauszman, Liming Wang, Andreas C. Hocke, Richard L. Proia, Jun Yin, Hanpo Yu, Hannes Ranke
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Hypoxic pulmonary vasoconstriction (HPV) optimizes pulmonary ventilation-perfusion matching in regional hypoxia, but promotes pulmonary hypertension in global hypoxia. Ventilation-perfusion mismatch is a major cause of hypoxemia in cystic fibrosis. W
Publikováno v:
Pneumologie. 68
Autor:
Sandra Lorena Colli, Nazarena Cardoso, Carla Antonella Massone, María Cores, Mercedes García Lombardi, Elena Noemí De Matteo, Mario Alejandro Lorenzetti, María Victoria Preciado
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266466 (2022)
ObjectivesTumors of the central nervous system (CNS) are the most common pediatric solid tumors, where low grade (LGG) and high grade gliomas (HGG) represent up to 55% of CNS tumors. Current molecular classification of these tumors results in a more
Externí odkaz:
https://doaj.org/article/4279b79ed5b44fbe84893586c39aad85
Autor:
Daniela Alejandra Rios, Paola Cecilia Casciato, María Soledad Caldirola, María Isabel Gaillard, Cecilia Giadans, Beatriz Ameigeiras, Elena Noemí De Matteo, María Victoria Preciado, Pamela Valva
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Chronic hepatitis C (CHC) pathogenic mechanisms as well as the participation of the immune response in the generation of liver damage are still a topic of interest. Here, we evaluated immune cell populations and cytokines in the liver and peripheral
Externí odkaz:
https://doaj.org/article/4aa481981e1c4b1c986b435bebc9035b