Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Elena N. Pugacheva"'
Autor:
Sila Yanardag, Elena N. Pugacheva
Publikováno v:
Cells, Vol 10, Iss 6, p 1428 (2021)
Signaling networks guide stem cells during their lineage specification and terminal differentiation. Primary cilium, an antenna-like protrusion, directly or indirectly plays a significant role in this guidance. All stem cells characterized so far hav
Externí odkaz:
https://doaj.org/article/11f47c7c6cef4e1e98fec0a9ae98c944
Autor:
Guo, Qing Ye, Jiajia Wang, Barbara Ducatman, Rebecca A. Raese, Jillian L. Rogers, Ying-Wooi Wan, Chunlin Dong, Lindsay Padden, Elena N. Pugacheva, Yong Qian, Nancy Lan
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10561
There is currently no gene expression assay that can assess if premalignant lesions will develop into invasive breast cancer. This study sought to identify biomarkers for selecting patients with a high potential for developing invasive carcinoma in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::cacf2195afb3ffa12d91627965d60747
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 608K, Supplementary Figure 6. A. Representative BLI of lungs dissected from 4 groups of mice after 2 weeks of treatment as in Fig.7A-B. B. Quantification of BLI of dissected lungs from mice as in (A); 3 independent experiments, n=6/group, Avera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5b84e4ab1fb6a91a961235fe49bb04
https://doi.org/10.1158/1541-7786.22511331.v1
https://doi.org/10.1158/1541-7786.22511331.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
Representative movie of individual MDA-MB-231LN cells treated with Vehicle, MLN8237, eribulin, or MLN8237/eribulin combination, suspended in collagen, and manually tracked over the course of 23 hours toward the serum chemoattractant-containing reserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7997dae0d7d254369c9e07211599f4ae
https://doi.org/10.1158/1535-7163.22508218
https://doi.org/10.1158/1535-7163.22508218
Autor:
Elena N. Pugacheva, Matthew B. Smolkin, Varvara K. Kozyreva, Kristina M. Marinak, Yuriy V. Loskutov, Laura C. Kelley, Brandon C. Jones
Ibidi chemotactic invasion of MDA-MB-231 cells with CA-RhoA overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9035c12b3f8bee82ad1db24dcf3b3dfc
https://doi.org/10.1158/1541-7786.22511755.v1
https://doi.org/10.1158/1541-7786.22511755.v1
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
The prometastatic protein NEDD9 (neural precursor cell expressed, developmentally downregulated 9) is highly expressed in many cancers and is required for mesenchymal individual cell migration and progression to the invasive stage. Nevertheless, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82643d1cf28555eff2e8c9f79dab9874
https://doi.org/10.1158/1541-7786.c.6539916.v1
https://doi.org/10.1158/1541-7786.c.6539916.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
File contains Supplementary figures: Figure 1: AUKRA analysis in TNBC cell lines in response to drug treatments. Additional TNBC migration/invasion analysis. Figure 2. Representative FACS analysis flow charts of TNBCs undergoing apoptosis. Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213ece0ad103527f71ce5fc1158f36c3
https://doi.org/10.1158/1535-7163.22508212
https://doi.org/10.1158/1535-7163.22508212
Autor:
Elena N. Pugacheva, Matthew B. Smolkin, Varvara K. Kozyreva, Kristina M. Marinak, Yuriy V. Loskutov, Laura C. Kelley, Brandon C. Jones
Commonly upregulated in human cancers, the scaffolding protein NEDD9/HEF1 is a known regulator of mesenchymal migration and cancer cell plasticity. However, the functional role of NEDD9 as a regulator of different migration/invasion modes in the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d056d499e1e3da99ce8ba4dc404907e
https://doi.org/10.1158/1541-7786.c.6540028.v1
https://doi.org/10.1158/1541-7786.c.6540028.v1
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 131K, Supplementary Figure 5. Rescue of NEDD9-knockdown with CTTN deacetylation mimicking mutant. Immunoprecipitation of CTTN or myc-CTTN with anti-CTTN or anti-myc antibodies from MDA-MB-231 cells co-transfected with siRNA against NEDD9 (N1) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06694b9c0a62360a4e9183a9f905443a
https://doi.org/10.1158/1541-7786.22511334
https://doi.org/10.1158/1541-7786.22511334
Autor:
Elena N. Pugacheva, Brandon C. Jones, Ryan J. Ice, Anuradha Rajulapati, Varvara K. Kozyreva, Yuriy V. Loskutov, Polina Y. Kozyulina
Supplementary Figure 3. (A). Quantification of volume of early endosomes based on 3D reconstructed confocal images of BT459-siCon, -siN2, -siN3) cells stained with EEA1 antibodies; mean volume (%) normalized to siCon+S.E.M; n=3, 10 cells/treatment; o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758a9e08b516fe81c6ca61469771d7fb
https://doi.org/10.1158/1541-7786.22517050.v1
https://doi.org/10.1158/1541-7786.22517050.v1