Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elena N Postnikova"'
Autor:
Elena N Postnikova, James Pettitt, Collin J Van Ryn, Michael R Holbrook, Laura Bollinger, Shuǐqìng Yú, Yíngyún Caì, Janie Liang, Michael C Sneller, Peter B Jahrling, Lisa E Hensley, Jens H Kuhn, Mosoka P Fallah, Richard S Bennett, Cavan Reilly
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221407 (2019)
Antibody titers against a viral pathogen are typically measured using an antigen binding assay, such as an enzyme-linked immunosorbent assay (ELISA), which only measures the ability of antibodies to identify a viral antigen of interest. Neutralizatio
Externí odkaz:
https://doaj.org/article/e7bb89cec8f840be8b1e3ed7a18f48ff
Autor:
Yíngyún Caì, Shu Qìng Yú, Elena N Postnikova, Steven Mazur, John G Bernbaum, Robin Burk, Téngfēi Zhāng, Sheli R Radoshitzky, Marcel A Müller, Ingo Jordan, Laura Bollinger, Lisa E Hensley, Peter B Jahrling, Jens H Kuhn
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112060 (2014)
Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently isolated betacoronavirus identified as the etiologic agent of a frequently fatal disease in Western Asia, Middle East respiratory syndrome. Attempts to identify the natural reservo
Externí odkaz:
https://doaj.org/article/7f52b184f1244d619c5045dcfc1e7e4b
Autor:
Yíngyún Caì, Masaharu Iwasaki, Brett F. Beitzel, Shuīqìng Yú, Elena N. Postnikova, Beatrice Cubitt, Lisa Evans DeWald, Sheli R. Radoshitzky, Laura Bollinger, Peter B. Jahrling, Gustavo F. Palacios, Juan C. de la Torre, Jens H. Kuhn
Publikováno v:
Viruses, Vol 10, Iss 11, p 655 (2018)
Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000⁻300,000 individuals yearly in western Africa and frequently causes lethal disease. Currently, no LASV-specific antivirals or vaccines are commercially available for prevention or tr
Externí odkaz:
https://doaj.org/article/cff65530011244159414a272e7224567
Autor:
Ryan P. Bennett, Elena N. Postnikova, Brett P. Eaton, Yingyun Cai, Shuiqing Yu, Charles O. Smith, Janie Liang, Huanying Zhou, Gregory A. Kocher, Michael J. Murphy, Harold C. Smith, Jens H. Kuhn
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Sangivamycin is a nucleoside analog that is well tolerated by humans and broadly active against phylogenetically distinct viruses, including arenaviruses, filoviruses, and orthopoxviruses. Here, we show that sangivamycin is a potent antiviral against
Externí odkaz:
https://doaj.org/article/b37aa9b5a1a447c7b6e4a792bd43f84d
Autor:
Yingyun Cai, Masaharu Iwasaki, Daisuke Motooka, David X. Liu, Shuiqing Yu, Kurt Cooper, Randy Hart, Ricky Adams, Tracey Burdette, Elena N. Postnikova, Jonathan Kurtz, Marisa St. Claire, Chengjin Ye, Jens H. Kuhn, Luis Martínez-Sobrido, Juan Carlos de la Torre
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Lassa virus (LASV) poses a significant public health problem within the regions of Lassa fever endemicity in Western Africa. LASV infects several hundred thousand individuals yearly, and a considerable number of Lassa fever cases are associa
Externí odkaz:
https://doaj.org/article/ff2f37fbb3974b63a94d0c00aaaa85fc
Autor:
Yingyun Cai, Chengjin Ye, Benson Cheng, Aitor Nogales, Masaharu Iwasaki, Shuiqing Yu, Kurt Cooper, David X. Liu, Randy Hart, Ricky Adams, Tyler Brady, Elena N. Postnikova, Jonathan Kurtz, Marisa St Claire, Jens H. Kuhn, Juan Carlos de la Torre, Luis Martínez-Sobrido
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Lassa virus (LASV) is endemic in Western Africa and is estimated to infect hundreds of thousands of individuals annually. A considerable number of these infections result in Lassa fever (LF), which is associated with significant morbidity an
Externí odkaz:
https://doaj.org/article/8cc7b2d7a47643b695aca684103bc6c5
Autor:
Brett F. Beitzel, Sheli R. Radoshitzky, Nicholas Di Paola, Jennifer M. Brannan, David Kimmel, Katie Caviness, Veronica Soloveva, Shuiqing Yu, Elena N. Postnikova, Courtney L. Finch, Hu Liu, Laura Prugar, Russell Bakken, John M. Dye, Jeffrey R. Kugelman, James M. Cunningham, Mariano Sanchez-Lockhart, Jens H. Kuhn, Gustavo Palacios
Publikováno v:
Viruses, Vol 13, Iss 10, p 2010 (2021)
Biosafety, biosecurity, logistical, political, and technical considerations can delay or prevent the wide dissemination of source material containing viable virus from the geographic origin of an outbreak to laboratories involved in developing medica
Externí odkaz:
https://doaj.org/article/0ee43d4ed623440aa0b0b3157867c4e1
Autor:
Yíngyún Caì, Shuǐqìng Yú, Rohit K. Jangra, Elena N. Postnikova, Jiro Wada, Robert B. Tesh, Sean P. J. Whelan, Michael Lauck, Michael R. Wiley, Courtney L. Finch, Sheli R. Radoshitzky, David H. O’Connor, Gustavo Palacios, Kartik Chandran, Charles Y. Chiu, Jens H. Kuhn
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
In 2012, the genome of a novel rhabdovirus, Bas-Congo virus (BASV), was discovered in the acute-phase serum of a Congolese patient with presumed viral hemorrhagic fever. In the absence of a replicating virus isolate, fulfilling Koch’s postulates to
Externí odkaz:
https://doaj.org/article/42d3e61b63e046b78abdb3e3b958cd09
Autor:
Richard S. Bennett, Elena N. Postnikova, Janie Liang, Robin Gross, Steven Mazur, Saurabh Dixit, Gregory Kocher, Shuiqing Yu, Shalamar Georgia-Clark, Dawn Gerhardt, Yingyun Cai, Lindsay Marron, Vladimir V. Lukin, Michael R. Holbrook
Publikováno v:
Viruses, Vol 13, Iss 5, p 893 (2021)
As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic expanded, it was clear that effective testing for the presence of neutralizing antibodies in the blood of convalescent patients would be critical for development of plasma-b
Externí odkaz:
https://doaj.org/article/68432f1b9ba54e99ab8e4d6f88032a51
Autor:
Yingyun Cai, Shuiqing Yu, Ying Fang, Laura Bollinger, Yanhua Li, Michael Lauck, Elena N. Postnikova, Steven Mazur, Reed F. Johnson, Courtney L. Finch, Sheli R. Radoshitzky, Gustavo Palacios, Thomas C. Friedrich, Tony L. Goldberg, David H. O’Connor, Peter B. Jahrling, Jens H. Kuhn
Publikováno v:
Viruses, Vol 13, Iss 4, p 632 (2021)
Simian hemorrhagic fever virus (SHFV) causes acute, lethal disease in macaques. We developed a single-plasmid cDNA-launch infectious clone of SHFV (rSHFV) and modified the clone to rescue an enhanced green fluorescent protein-expressing rSHFV-eGFP th
Externí odkaz:
https://doaj.org/article/08ef1d71cf0b4f279e588db0414e4ac3