Chemical Antibody Mimics Inhibit Cadherin-Mediated Cell-Cell Adhesion: A Promising Strategy for Cancer Therapy

Autor: Elena Moroni, Levi A. Gheber, Paulina X. Medina Rangel, Franck Merlier, Bernadette Tse Sum Bui, Karsten Haupt, Razi Vago

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2020, 59 (7), pp.2816-2822. ⟨10.1002/anie.201910373⟩

One of the most promising strategies to treat cancer is the use of therapeutic antibodies that disrupt cell-cell adhesion mediated by dysregulated cadherins. The principal site where cell-cell adhesion occurs encompasses Trp2 found at the N-terminal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32270fd9bf37544481c6e9a030dfb6ff
https://hal.utc.fr/hal-02362795

Association of functional, inherited vitamin D-binding protein variants with melanoma-specific death.

Autor: Gibbs DC; Department of Dermatology, Emory University, Atlanta, GA, USA., Thomas NE; Department of Dermatology, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA., Kanetsky PA; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Luo L; Department of Internal Medicine, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM, USA., Busam KJ; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cust AE; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia.; Melanoma Institute Australia, The University of Sydney, Sydney, NSW, Australia., Anton-Culver H; Department of Epidemiology, University of California, Irvine, CA, USA., Gallagher RP; Cancer Control Research, British Columbia Cancer and Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada., Zanetti R; Center for Cancer Prevention, Piedmont Cancer Registry, Torino, Italy.; Fondo Elena Moroni for Oncology, Torino, Italy.; Department of Surgery, University of North Carolina, Chapel Hill, NC, USA., Rosso S; Center for Cancer Prevention, Piedmont Cancer Registry, Torino, Italy.; Fondo Elena Moroni for Oncology, Torino, Italy.; Department of Surgery, University of North Carolina, Chapel Hill, NC, USA., Sacchetto L; Center for Cancer Prevention, Piedmont Cancer Registry, Torino, Italy.; Fondo Elena Moroni for Oncology, Torino, Italy.; Department of Surgery, University of North Carolina, Chapel Hill, NC, USA., Edmiston SN; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA., Conway K; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Epidemiology, Gillings Global School of Public Health, University of North Carolina, Chapel Hill, NC, USA., Ollila DW; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Surgery, University of North Carolina, Chapel Hill, NC, USA., Begg CB; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Berwick M; Department of Internal Medicine, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM, USA., Ward SV; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; School of Population and Global Health, The University of Western Australia, Perth, WA, Australia., Orlow I; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Publikováno v: JNCI cancer spectrum [JNCI Cancer Spectr] 2023 Aug 31; Vol. 7 (5).

Cigarettes smoking and androgen receptor-positive breast cancer.

Autor: Pizzato M; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan., Carioli G; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan., Rosso S; Piedmont Cancer Registry, A.O.U, Citta` della Salute e della Scienza di Torino., Zanetti R; Piedmont Cancer Registry, A.O.U, Citta` della Salute e della Scienza di Torino.; Fondo Elena Moroni for Oncology, Turin., Negri E; Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan, Italy., La Vecchia C; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan.

Publikováno v: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) [Eur J Cancer Prev] 2021 Nov 01; Vol. 30 (6), pp. 469-471.

The impact of selected risk factors among breast cancer molecular subtypes: a case-only study.

Autor: Pizzato M; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Via Augusto Vanzetti 5, 20133, Milano, Milan, Italy., Carioli G; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Via Augusto Vanzetti 5, 20133, Milano, Milan, Italy. greta.carioli@unimi.it., Rosso S; Piedmont Cancer Registry, Città della Salute e della Scienza di Torino, A.O.U, Turin, Italy., Zanetti R; Piedmont Cancer Registry, Città della Salute e della Scienza di Torino, A.O.U, Turin, Italy.; Fondo Elena Moroni for Oncology., La Vecchia C; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Via Augusto Vanzetti 5, 20133, Milano, Milan, Italy.

Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2020 Nov; Vol. 184 (1), pp. 213-220. Date of Electronic Publication: 2020 Aug 26.