Oligosymptomatic long-term carriers of SARS-CoV-2 display impaired innate resistance but increased high-affinity anti-spike antibodies

Autor: Elena Montes-Cobos, Victoria C. Bastos, Clarice Monteiro, João C.R. de Freitas, Heiny D.P. Fernandes, Clarice S. Constancio, Danielle A.S. Rodrigues, Andreza M.D.S. Gama, Vinicius M. Vidal, Leticia S. Alves, Laura Zalcberg-Renault, Guilherme S. de Lira, Victor A. Ota, Carolina Caloba, Luciana Conde, Isabela C. Leitão, Amilcar Tanuri, Orlando D.C. Ferreira, Renata M. Pereira, André M. Vale, Terezinha M. Castiñeiras, Dominique Kaiserlian, Juliana Echevarria-Lima, Marcelo T. Bozza

Publikováno v: iScience, Vol 26, Iss 7, Pp 107219- (2023)

Summary: The vast spectrum of clinical features of COVID-19 keeps challenging scientists and clinicians. Low resistance to infection might result in long-term viral persistence, but the underlying mechanisms remain unclear. Here, we studied the immun

Externí odkaz: https://doaj.org/article/3fbe702109ad4297862b695b0d6f52bc

Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.

Autor: Elena Montes-Cobos, Xiao Li, Henrike J Fischer, André Sasse, Sebastian Kügler, Michael Didié, Karl Toischer, Martin Fassnacht, Ralf Dressel, Holger M Reichardt

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0143954 (2015)

Mineralocorticoid receptor (MR) inactivation in mice results in early postnatal lethality. Therefore we generated mice in which MR expression can be silenced during adulthood by administration of doxycycline (Dox). Using a lentiviral approach, we obt

Externí odkaz: https://doaj.org/article/24b56fc18aaa4e4da2c311270cbb4f41

Author response for 'MIF is essential to the establishment of house dust mite‐induced airway inflammation and tissue remodeling in mice'

Autor: null Leticia Lintomen, null Luciana M. Kluppel, null Jamil Z. Kitoko, null Elena Montes‐Cobos, null Vinícius Mendes Vidal, null Luis Batista Tan, null José Nazioberto de Farias, null Heitor S. de Souza, null Priscilla C. Olsen, null Marcelo T. Bozza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5060d586108da458ea1158287485ab2
https://doi.org/10.1002/eji.202250016/v3/response1

Skeletal and Dental Morphological Characteristics of the Maxillary in Patients with Impacted Canines Using Cone Beam Computed Tomography: A Retrospective Clinical Study

Autor: María Elena Montes-Díaz, Alicia Martínez-González, Riánsares Arriazu-Navarro, Alfonso Alvarado-Lorenzo, Nuria Esther Gallardo-López, Ricardo Ortega-Aranegui

Publikováno v: Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 12, Iss 96, p 96 (2022)
Journal of Personalized Medicine; Volume 12; Issue 1; Pages: 96

The aim of this study is to analyze the skeletal and dentoalveolar morphological characteristics of the maxillary in subjects with a unilateral palatally impacted canine using Cone Beam Computed Tomography (CBCT). A retrospective clinical study was c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb476148bf84a360a7bfbb468df5a32
https://pubmed.ncbi.nlm.nih.gov/35055411

Voltage-Gated Proton Channel Hv1 Controls TLR9 Activation in Plasmacytoid Dendritic Cells

Autor: Simone Bauer, Jan Broder Engler, Nina Kursawe, Marcel S Woo, Michael Moles, Friederike Ufer, Britta Huscher, Elena Montes-Cobos, Lars Binkle, Manuel A. Friese

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 205(11)

The voltage-gated proton channel Hv1 regulates proton fluxes across membranes, thereby influencing pH-dependent processes. Plasmacytoid dendritic cells (pDCs) require a particularly tight regulation of endosomal pH to ensure strong type I IFN secreti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82456f3a46fb03c3bd4219f01b72287
https://pubmed.ncbi.nlm.nih.gov/33127821