Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Elena Mitsi"'
Autor:
Elena Mitsi, Mariana O. Diniz, Jesús Reiné, Andrea M. Collins, Ryan E. Robinson, Angela Hyder-Wright, Madlen Farrar, Konstantinos Liatsikos, Josh Hamilton, Onyia Onyema, Britta C. Urban, Carla Solórzano, Sandra Belij-Rammerstorfer, Emma Sheehan, Teresa Lambe, Simon J. Draper, Daniela Weiskopf, Alessandro Sette, Mala K. Maini, Daniela M. Ferreira
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Respiratory mucosal immunity induced by vaccination is vital for protection from coronavirus infection in animal models. In humans, the capacity of peripheral vaccination to generate sustained immunity in the lung mucosa, and how this is inf
Externí odkaz:
https://doaj.org/article/6d44bf59f3084d30b1170569d157d5ea
Autor:
Maia Lesosky, Konstantinos Liatsikos, Stephen B Gordon, Kelly Davies, Phoebe Hazenberg, Angela Hyder-Wright, Ryan E Robinson, Britta Urban, Elena Mitsi, Carla Solorzano, Daniela M Ferreira, Madlen Farrar, Ashleigh Howard, Andrea M Collins, Jaye Brunning, Hannah Fleet, Amy Bettam, Tinashe Kenny-Nyazika, Dima El Safadi
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Since the introduction of pneumococcal conjugate vaccines, pneumococcal disease rates have declined for many vaccine-type serotypes. However, serotype 3 (SPN3) continues to cause significant disease and is identified in colonisation epid
Externí odkaz:
https://doaj.org/article/29c9f5f36e564dbebdfe5cbccf615b4d
Autor:
Ryan E Robinson, Christopher Myerscough, Nengjie He, Helen Hill, Wendi A Shepherd, Patricia Gonzalez-Dias, Konstantinos Liatsikos, Samuel Latham, Fred Fyles, Klara Doherty, Phoebe Hazenberg, Fathimath Shiham, Daniella Mclenghan, Hugh Adler, Vicki Randles, Seher Zaidi, Angela Hyder-Wright, Elena Mitsi, Hassan Burhan, Ben Morton, Jamie Rylance, Maia Lesosky, Stephen B Gordon, Andrea M Collins, Daniela M Ferreira
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0284399 (2023)
IntroductionExperimental Human Pneumococcal Challenge (EHPC) involves the controlled exposure of adults to a specific antibiotic-sensitive Streptococcus pneumoniae serotype, to induce nasopharyngeal colonisation for the purpose of vaccine research. T
Externí odkaz:
https://doaj.org/article/5ba86a5041f341e7abc5a37ebce3456c
Autor:
Naomi F Walker, Rachel L Byrne, Ashleigh Howard, Elissavet Nikolaou, Madlen Farrar, Sharon Glynn, Katerina S Cheliotis, Ana I Cubas Atienzar, Kelly Davies, Jesús Reiné, Zalina Rashid-Gardner, Esther L German, Carla Solórzano, Tess Blandamer, Lisa Hitchins, Christopher Myerscough, Bradford D Gessner, Elizabeth Begier, Andrea M Collins, Mike Beadsworth, Stacy Todd, Helen Hill, Catherine F Houlihan, Eleni Nastouli, Emily R Adams, Elena Mitsi, Daniela M Ferreira, SAFER investigators
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280908 (2023)
BackgroundThe SARS-CoV-2 pandemic has caused an unprecedented strain on healthcare systems worldwide, including the United Kingdom National Health Service (NHS). We conducted an observational cohort study of SARS-CoV-2 infection in frontline healthca
Externí odkaz:
https://doaj.org/article/2f8d87f300ff42ec98b0540f44bdb8b9
Autor:
Elissavet Nikolaou, Esther L. German, Annie Blizard, Ashleigh Howard, Lisa Hitchins, Tao Chen, Jim Chadwick, Sherin Pojar, Elena Mitsi, Carla Solórzano, Syba Sunny, Felicity Dunne, Jenna F. Gritzfeld, Hugh Adler, Jason Hinds, Katherine A. Gould, Jamie Rylance, Andrea M. Collins, Stephen B. Gordon, Daniela M. Ferreira
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Previous studies have suggested that the pneumococcal niche changes from the nasopharynx to the oral cavity with age. We use an Experimental Human Pneumococcal Challenge model to investigate pneumococcal colonisation in different anatomical
Externí odkaz:
https://doaj.org/article/e86701c2f70341c0a89b2827ecb7542b
Autor:
Tao Chen, Duolao Wang, Konstantinos Liatsikos, Stephen B Gordon, Hassan Burhan, Ben Morton, Tinashe K Nyazika, Bradford D Gessner, Helen Hill, Andrea Collins, Josh Hamilton, Kelly Davies, Fred Fyles, Phoebe Hazenberg, Elizabeth Begier, Angela Hyder-Wright, Sherin Pojar, Christopher Myerscough, Jesus Reine, Ryan E Robinson, Britta Urban, Elena Mitsi, Carla Solorzano, Angela Quinn, Kaijie Pan, Annaliesa S Anderson, Christian Theilacker, Daniela M Ferreira, Kelly Convey, James Court, Madlen Farrar, Lisa Hitchins, Ashleigh Howard, Lauren Kerruish, Samuel Latham, Annabel Murphy, Elissavet Nikolaou, Angelina Peterson
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Introduction Despite widely available vaccinations, Streptococcus pneumoniae (SPN) remains a major cause of morbidity and mortality worldwide, causing community-acquired pneumonia, meningitis, otitis media, sinusitis and bacteraemia. Here, we summari
Externí odkaz:
https://doaj.org/article/13a7b19514ce48c68e2c73bb6ee12be9
Autor:
Simon P. Jochems, Karin de Ruiter, Carla Solórzano, Astrid Voskamp, Elena Mitsi, Elissavet Nikolaou, Beatriz F. Carniel, Sherin Pojar, Esther L. German, Jesús Reiné, Alessandra Soares-Schanoski, Helen Hill, Rachel Robinson, Angela D. Hyder-Wright, Caroline M. Weight, Pascal F. Durrenberger, Robert S. Heyderman, Stephen B. Gordon, Hermelijn H. Smits, Britta C. Urban, Jamie Rylance, Andrea M. Collins, Mark D. Wilkie, Lepa Lazarova, Samuel C. Leong, Maria Yazdanbakhsh, Daniela M. Ferreira
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/bcadd546859142bdac48336b2764f1e0
Autor:
Lucille F. van Beek, Kristin Surmann, H. Bart van den Berg van Saparoea, Diane Houben, Wouter S. P. Jong, Christian Hentschker, Thomas H. A. Ederveen, Elena Mitsi, Daniela M. Ferreira, Fred van Opzeeland, Christa E. van der Gaast – de Jongh, Irma Joosten, Uwe Völker, Frank Schmidt, Joen Luirink, Dimitri A. Diavatopoulos, Marien I. de Jonge
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1310-1328 (2020)
Nasopharyngeal colonization by Streptococcus pneumoniae is a prerequisite for pneumococcal transmission and disease. Current vaccines protect only against disease and colonization caused by a limited number of serotypes, consequently allowing serotyp
Externí odkaz:
https://doaj.org/article/3e016418b8e44a38bee691ecfa6505c3
Autor:
Katerina S. Cheliotis, Christopher P. Jewell, Carla Solórzano, Britta Urban, Andrea M. Collins, Elena Mitsi, Sherin Pojar, Elissavet Nikolaou, Esther L. German, Jesús Reiné, Stephen B. Gordon, Simon P. Jochems, Jamie Rylance, Daniela M. Ferreira
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Streptococcus pneumoniae (pneumococcus) is the most commonly identified bacterial cause of pneumonia and the leading infectious cause of death in children under 5 years of age worldwide. Pneumococcal disease follows a seasonal pattern with increased
Externí odkaz:
https://doaj.org/article/02f21473f41241cd9746bf539d810172
Autor:
Elena Mitsi, Jesús Reiné, Britta C. Urban, Carla Solórzano, Elissavet Nikolaou, Angela D. Hyder-Wright, Sherin Pojar, Ashleigh Howard, Lisa Hitchins, Sharon Glynn, Madlen C. Farrar, Konstantinos Liatsikos, Andrea M. Collins, Naomi F. Walker, Helen C. Hill, Esther L. German, Katerina S. Cheliotis, Rachel L. Byrne, Christopher T. Williams, Ana I. Cubas-Atienzar, Tom E. Fletcher, Emily R. Adams, Simon J. Draper, David Pulido, Rohini Beavon, Christian Theilacker, Elizabeth Begier, Luis Jodar, Bradford D. Gessner, Daniela M. Ferreira
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 7 (2022)
Background Although recent epidemiological data suggest that pneumococci may contribute to the risk of SARS-CoV-2 disease, cases of coinfection with Streptococcus pneumoniae in patients with coronavirus disease 2019 (COVID-19) during hospitalization
Externí odkaz:
https://doaj.org/article/b2d172fcc22a4eafaa71e455bedd326d