Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Elena Miranda"'
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 24, Iss 12, p 354 (2023)
Background: Cardiovascular disease that is caused by atherosclerosis is the leading cause of death worldwide. Atherosclerosis is primarily triggered by endothelial dysfunction and the accumulation of modified low-density lipoprotein (LDL) particles i
Externí odkaz:
https://doaj.org/article/1618bf548046496ea6446307c90b62e2
Autor:
Micaela Harrasser, Satyen Harish Gohil, Hiu Lau, Marco Della Peruta, Vincent Muczynski, Dominic Patel, Elena Miranda, Kristiana Grigoriadis, Anita Grigoriadis, David Granger, Rachel Evans, Amit Chunilal Nathwani
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background Chimeric antigen receptor (CAR)-T cells can induce powerful immune responses in patients with hematological malignancies but have had limited success against solid tumors. This is in part due to the immunosuppressive tumor microen
Externí odkaz:
https://doaj.org/article/525e45b55e49442f8728048752ec16ba
Autor:
Alexa Núñez, Irene Belmonte, Elena Miranda, Miriam Barrecheguren, Georgina Farago, Eduardo Loeb, Mònica Pons, Francisco Rodríguez-Frías, Pablo Gabriel-Medina, Esther Rodríguez, Joan Genescà, Marc Miravitlles, Cristina Esquinas
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Alpha-1 antitrypsin deficiency (AATD) is considered one of the most common genetic diseases and is characterised by the misfolding and polymerisation of the alpha-1 antitrypsin (AAT) protein within hepatocytes. The relevance of ci
Externí odkaz:
https://doaj.org/article/cd8d8ee98332434e8f0d57fdac620e79
Autor:
Thies Ingwersen, Christian Linnenberg, Emanuela D’Acunto, Shabnam Temori, Irene Paolucci, David Wasilewski, Behnam Mohammadi, Johannes Kirchmair, Robert C. Glen, Elena Miranda, Markus Glatzel, Giovanna Galliciotti
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a progressive neurodegenerative disease caused by point mutations in the gene for neuroserpin, a serine protease inhibitor of the nervous system. Different mutations are kn
Externí odkaz:
https://doaj.org/article/82d3602c215e4fa28f209ae781dcc486
Autor:
Elena Miranda, Giovanna Galliciotti
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 8, Pp 1733-1734 (2022)
Externí odkaz:
https://doaj.org/article/02d3f9656e454d87aabfd1fcfe3804ad
Autor:
Jose-M Ramirez-Rodriguez, Javier Martinez-Ubieto, Jose-L Muñoz-Rodes, Jose-R Rodriguez-Fraile, Jose-A Garcia-Erce, Javier Blanco-Gonzalez, Emilio Del Valle-Hernandez, Eugenia Centeno-Robles, Carolina Martinez-Perez, Miguel Leon-Arellano, Estibaliz Echazarreta-Gallego, Manuela Elia-Guedea, Ana Pascual-Bellosta, Elena Miranda-Tauler, Alba Manuel-Vazquez, Enrique Balen-Rivera, David Alvarez-Martinez, Jose Perez-Peña, Elisabeth Redondo-Villahoz, Elena Biosta-Perez, Hector Guadalajara-Labajo, Cristina Latre-Saso, Elena Cordoba-Diaz de Laspra, Luis Sanchez-Guillen, Mercedes Cabellos-Olivares, Javier Longas-Valien, Sonia Ortega-Lucea, Julia Ocon-Breton, Antonio Arroyo-Sebastian, Damian Garcia-Olmo
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Introduction The evidence currently available from enhanced recovery after surgery (ERAS) programmes concerns their benefits in the immediate postoperative period, but there is still very little evidence as to whether their correct implementation ben
Externí odkaz:
https://doaj.org/article/e62f61cc66df4e3982351d68a0a6e35c
Autor:
Matthew W. Fittall, William Mifsud, Nischalan Pillay, Hongtao Ye, Anna-Christina Strobl, Annelien Verfaillie, Jonas Demeulemeester, Lei Zhang, Fitim Berisha, Maxime Tarabichi, Matthew D. Young, Elena Miranda, Patrick S. Tarpey, Roberto Tirabosco, Fernanda Amary, Agamemnon E. Grigoriadis, Michael R. Stratton, Peter Van Loo, Cristina R. Antonescu, Peter J. Campbell, Adrienne M. Flanagan, Sam Behjati
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
FOS has been linked to bone tumour pathogenesis, and viral homologue v-fos causes osteosarcoma in mice. Here, the authors report rearrangement of FOS and its paralogue FOSB in osteoblastoma and osteoid osteoma, revealing human bone tumours that are d
Externí odkaz:
https://doaj.org/article/e874f5cac91c4dfcb8f739743873d777
Autor:
Alexa Núñez, Irene Belmonte, Elena Miranda, Miriam Barrecheguren, Georgina Farago, Eduardo Loeb, Mònica Pons, Francisco Rodríguez-Frías, Pablo Gabriel-Medina, Esther Rodríguez, Joan Genescà, Marc Miravitlles, Cristina Esquinas
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/e892040793554a46b7dcd3bd3b28e6ff
Autor:
Valentina Vapore, Corrado Mazzaglia, Diego Sibilia, Mara Del Vecchio, Gernot Fruhmann, Marta Valenti, Elena Miranda, Teresa Rinaldi, Joris Winderickx, Cristina Mazzoni
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1498 (2021)
FENIB (familial encephalopathy with neuroserpin inclusion bodies) is a human monogenic disease caused by point mutations in the SERPINI1 gene, characterized by the intracellular deposition of polymers of neuroserpin (NS), which leads to proteotoxicit
Externí odkaz:
https://doaj.org/article/7726b019a1154a09aed2e73f897d20c7
Autor:
Riccardo Ronzoni, Ilaria Ferrarotti, Emanuela D’Acunto, Alice M. Balderacchi, Stefania Ottaviani, David A. Lomas, James A. Irving, Elena Miranda, Annamaria Fra
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5668 (2021)
Alpha-1-antitrypsin (AAT) deficiency causes pulmonary disease due to decreased levels of circulating AAT and consequently unbalanced protease activity in the lungs. Deposition of specific AAT variants, such as the common Z AAT, within hepatocytes may
Externí odkaz:
https://doaj.org/article/60628c5796ca46fe8964acc684f1df3e