Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elena Martínez-Terroba"'
Autor:
Ivana Grbesa, María J Pajares, Elena Martínez-Terroba, Jackeline Agorreta, Ana-Matea Mikecin, Marta Larráyoz, Miguel A Idoate, Koraljka Gall-Troselj, Ruben Pio, Luis M Montuenga
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124670 (2015)
BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) are NAD+-dependent protein deacetylases involved in the regulation of key cancer-associated genes. In this study we evaluated the relevance of these deacetylases in lung cancer biology. MATERIAL AND
Externí odkaz:
https://doaj.org/article/4a5e947f31154ebf86d37dc3155d1bc8
Autor:
Jordan Bendor, Jesse R. Zamudio, Nadya Dimitrova, Elena Martínez-Terroba, Christiane E. Olivero, David M. Feldser, Lauren Winkler, Kevin Chen, Ephrath Tesfaye
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance The work by Tesfaye and colleagues defines universal and tumor type–specific features of the p53 tumor suppressor transcriptional network. This study determines a “core” signature of the p53 response across different oncogenic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273e76fc7f85dbf5fc5c7ee82e1b59f2
https://escholarship.org/uc/item/5h27x8c5
https://escholarship.org/uc/item/5h27x8c5
Autor:
Elena Martínez-Terroba, Fernando J. de Miguel, Camila Robles-Oteiza, Katerina Politi, Nadya Dimitrova
Publikováno v:
Cancer Research. 82:1540-1540
The identification and functional characterization of long noncoding RNAs (lncRNAs) have suggested a potential source of unexplored cancer therapy targets. The metastasis-associated lung adenocarcinoma transcript 1 (Malat1) was initially identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d48ede4da49015289e4fe206f776eae
https://doi.org/10.1158/1538-7445.am2022-1540
https://doi.org/10.1158/1538-7445.am2022-1540
Publikováno v:
The Journal of Cell Biology
Martínez-Terroba and Dimitrova preview work from Athie et al., which demonstrates that the lncRNA ALAL-1 promotes lung cancer cell proliferation and immune evasion.
Athie et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201908078) identi
Athie et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201908078) identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969dd8c40fc55cabc75c2774ccbdc1fd
https://doi.org/10.1083/jcb.202007098
https://doi.org/10.1083/jcb.202007098
Autor:
Cristina Bértolo, Maria J. Pajares, Ruben Pio, Cristina Sainz, Ignacio I. Wistuba, Teresa Ezponda, Elena Martínez-Terroba, Irati Garmendia, Jackeline Agorreta, Ana Remirez, Carmen Behrens, Luis M. Montuenga
Publikováno v:
Laboratory Investigation. 98:1562-1574
In recent years, the relevance of RNA metabolism has been increasingly recognized in a variety of diseases. Modifications in the levels of RNA-binding proteins elicit changes in the expression of cancer-related genes. Here we evaluate whether SRSF1 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869e7e81214950890ca22750b7a0aa52
https://doi.org/10.1038/s41374-018-0128-2
https://doi.org/10.1038/s41374-018-0128-2
Autor:
Carmen Behrens, Cristina Sainz, Maria J. Pajares, Fernando J. de Miguel, Luis M. Montuenga, Miguel Mesa-Guzman, Eduard Monsó, Jackeline Agorreta, Elena Martínez-Terroba, Ruben Pio, Javier J. Zulueta, Jose Luis Perez-Gracia, Ignacio I. Wistuba, Maria D. Lozano, Laura Millares
Publikováno v:
The Journal of Pathology. 245:421-432
Each of the pathological stages (I-IIIa) of surgically resected non-small-cell lung cancer has hidden biological heterogeneity, manifested as heterogeneous outcomes within each stage. Thus, the finding of robust and precise molecular classifiers with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39fb2423666c776f7778ecd4e5958f5a
https://doi.org/10.1002/path.5096
https://doi.org/10.1002/path.5096
Autor:
Silvestre Vicent, Eloisa Jantus-Lewintre, Elena Martínez-Terroba, Carlos Camps, Naiara Perurena, Carolina Zandueta, Ruben Pio, Sergio Ortiz-Espinosa, Fernando Lecanda, Maria J. Pajares, Leticia Corrales, Daniel Ajona, Luis M. Montuenga, Fernando J. de Miguel, Haritz Moreno, Jackeline Agorreta
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 197:1164-1176
C5aR1 (CD88), a receptor for complement anaphylatoxin C5a, is a potent immune mediator. Its impact on malignant growth and dissemination of non-small cell lung cancer cells is poorly understood.To investigate the contribution of the C5a/C5aR1 axis to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a9a445c5ca3db7ca710cda45160fef
https://doi.org/10.1164/rccm.201703-0660oc
https://doi.org/10.1164/rccm.201703-0660oc
Autor:
Clara Liao, Nima Hooshdaran, Jeremy A. Schofield, Nadya Dimitrova, Jesse R. Zamudio, Christiane E. Olivero, Matthew D. Simon, Jordan Bendor, Elena Martínez-Terroba, Ephrath Tesfaye, Dorthy Fang, Joshua T. Zimmer
Publikováno v:
Mol Cell
Summary The tumor suppressor p53 transcriptionally activates target genes to suppress cellular proliferation during stress. p53 has also been implicated in the repression of the proto-oncogene Myc, but the mechanism has remained unclear. Here, we ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8390490f90e5bf48b7279fd18b1c6562
https://pubmed.ncbi.nlm.nih.gov/31973890
https://pubmed.ncbi.nlm.nih.gov/31973890
Autor:
Nadya Dimitrova, Christiane E. Olivero, Ephrath Tesfaye, Elena Martínez-Terroba, Jordan Bendor, Jesse R. Zamudio, Clara Liao, Nima Hooshdaran
Publikováno v:
SSRN Electronic Journal.
The p53 pathway is a key tumor suppressor mechanism that stalls cell cycle progression in response to stress. It has been proposed that p53 suppresses proliferation in part by downregulating the Myc oncogene but the mechanism has remained unclear. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::078799a4d28d7602e1f7abe320516dfd
https://doi.org/10.2139/ssrn.3353218
https://doi.org/10.2139/ssrn.3353218
Autor:
W. Torre, Eduard Monsó, Elena Martínez-Terroba, Enriqueta Felip, Juan P. de-Torres, Luis M. Montuenga, Ana Remirez, Jackeline Agorreta, Carmen Behrens, Miguel Angel Idoate, Jose Luis Ramirez, Ignacio Gil-Bazo, Maria J. Pajares, Ruben Pio, Ignacio I. Wistuba, Rafael Rosell, Laura Millares
Publikováno v:
Thorax
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
IntroductionPrognostic biomarkers have been very elusive in the lung squamous cell carcinoma (SCC) and none is currently being used in the clinical setting. We aimed to identify and validate the clinical utility of a protein-based prognostic signatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3666a0d0048b970c16fb390e45569766
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3091
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3091