Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elena Marchisella"'
Autor:
Marion Bonneau, Shane T. O’ Sullivan, Miguel A. Gonzalez-Lozano, Paul Baxter, Phillippe Gautier, Elena Marchisella, Neil R. Hardingham, Robert A. Chesters, Helen Torrance, David M. Howard, Maurits A. Jansen, Melanie McMillan, Yasmin Singh, Michel Didier, Frank Koopmans, Colin A. Semple, Andrew M. McIntosh, Hansjürgen Volkmer, Maarten Loos, Kevin Fox, Giles E. Hardingham, Anthony C. Vernon, David J. Porteous, August B. Smit, David J. Price, J. Kirsty Millar
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract A balanced t(1;11) translocation that directly disrupts DISC1 is linked to schizophrenia and affective disorders. We previously showed that a mutant mouse, named Der1, recapitulates the effect of the translocation upon DISC1 expression. Here
Externí odkaz:
https://doaj.org/article/392e0db05f914e418b87d06cd79f30fb
Autor:
Marion Bonneau, Miguel A. Gonzalez-Lozano, August B. Smit, David M. Howard, David Price, Paul Baxter, Melanie McMillan, Anthony C. Vernon, J. Kirsty Millar, Colin A. Semple, Giles E. Hardingham, Shane T. O’ Sullivan, Helen S. Torrance, Robert A. Chesters, David J. Porteous, Hansjürgen Volkmer, Elena Marchisella, Yasmin Singh, Kevin Fox, Neil Robert Hardingham, Maurits A. Jansen, Andrew M. McIntosh, Frank Koopmans, Phillippe Gautier, Maarten Loos, Michel Didier
Publikováno v:
Translational Psychiatry
Bonneau, M, O'Sullivan, S T, Gonzalez-Lozano, M A, Baxter, P, Gautier, P, Marchisella, E, Hardingham, N R, Chesters, R A, Singh, Y, Didier, M, Koopmans, F, Semple, C A, McIntosh, A M, Volkmer, H, Loos, M, Fox, K, Hardingham, G, Vernon, A C, Porteous, D J, Smit, A B, Price, D & Millar, J K 2021, ' Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness ', Translational Psychiatry . https://doi.org/10.1038/s41398-021-01256-3
Translational Psychiatry, 11(1):135. Nature Publishing Group
Translational Psychiatry, Vol 11, Iss 1, Pp 1-16 (2021)
Bonneau, M, Sullivan, S T O, Gonzalez-Lozano, M A, Baxter, P, Gautier, P, Marchisella, E, Hardingham, N R, Chesters, R A, Torrance, H, Howard, D M, Jansen, M A, McMillan, M, Singh, Y, Didier, M, Koopmans, F, Semple, C A, McIntosh, A M, Volkmer, H, Loos, M, Fox, K, Hardingham, G E, Vernon, A C, Porteous, D J, Smit, A B, Price, D J & Kirsty Millar, J 2021, ' Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness ', Translational Psychiatry, vol. 11, no. 1, 135 . https://doi.org/10.1038/s41398-021-01256-3
Bonneau, M, O'Sullivan, S T, Gonzalez-Lozano, M A, Baxter, P, Gautier, P, Marchisella, E, Hardingham, N R, Chesters, R A, Singh, Y, Didier, M, Koopmans, F, Semple, C A, McIntosh, A M, Volkmer, H, Loos, M, Fox, K, Hardingham, G, Vernon, A C, Porteous, D J, Smit, A B, Price, D & Millar, J K 2021, ' Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness ', Translational Psychiatry . https://doi.org/10.1038/s41398-021-01256-3
Translational Psychiatry, 11(1):135. Nature Publishing Group
Translational Psychiatry, Vol 11, Iss 1, Pp 1-16 (2021)
Bonneau, M, Sullivan, S T O, Gonzalez-Lozano, M A, Baxter, P, Gautier, P, Marchisella, E, Hardingham, N R, Chesters, R A, Torrance, H, Howard, D M, Jansen, M A, McMillan, M, Singh, Y, Didier, M, Koopmans, F, Semple, C A, McIntosh, A M, Volkmer, H, Loos, M, Fox, K, Hardingham, G E, Vernon, A C, Porteous, D J, Smit, A B, Price, D J & Kirsty Millar, J 2021, ' Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness ', Translational Psychiatry, vol. 11, no. 1, 135 . https://doi.org/10.1038/s41398-021-01256-3
A balanced t(1;11) translocation that directly disrupts DISC1 is linked to schizophrenia and affective disorders. We previously showed that a mutant mouse, named Der1, recapitulates the effect of the translocation upon DISC1 expression. Here, RNAseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec9ede85fe60b13181f0fa5892a8983
https://pubmed.ncbi.nlm.nih.gov/33608504
https://pubmed.ncbi.nlm.nih.gov/33608504
Publikováno v:
Genes, Brain and Behavior. 17:56-69
The receptor tyrosine kinase ErbB4 and its ligand trophic factors of the neuregulin (NRG) family have been associated with schizophrenia and other mental disorders in human genetic studies. In vivo studies in mice have shown how abnormal Nrg-ErbB4 si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77be34e35f11cd918b2e2ceaf8973b80
https://doi.org/10.1111/gbb.12402
https://doi.org/10.1111/gbb.12402