Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Elena M. Ribe"'
Autor:
Evangeline M. Foster, Marco Fernandes, Adria Dangla-Valls, Philip Hublitz, Menelaos Pangalos, Simon Lovestone, Elena M. Ribe, Noel J. Buckley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Clusterin (CLU) is one of the most significant genetic risk factors for late onset Alzheimer’s disease (AD). However, the mechanisms by which CLU contributes to AD development and pathogenesis remain unclear. Studies have demonstrated that
Externí odkaz:
https://doaj.org/article/958cb5e0db16446a82e350c2c4f5ce28
Autor:
Ana Martín-Sánchez, Janet Piñero, Lara Nonell, Magdalena Arnal, Elena M. Ribe, Alejo Nevado-Holgado, Simon Lovestone, Ferran Sanz, Laura I. Furlong, Olga Valverde
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background Major depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer’s disease (AD). Despite both diseases having a robust genetic component, the common transcrip
Externí odkaz:
https://doaj.org/article/4bb29b8200dd48c7a1e162b9f080fde8
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in several physiological and pathological states, including Alzheimer’s disease (AD). With a prominent extracellular chaperone function, additional roles have been d
Externí odkaz:
https://doaj.org/article/01f4625ad99e4156b0961d59786152a6
Autor:
Jacqueline P. Robbins, Leo Perfect, Elena M. Ribe, Marcello Maresca, Adrià Dangla-Valls, Evangeline M. Foster, Richard Killick, Paulina Nowosiad, Matthew J. Reid, Lucia Dutan Polit, Alejo J. Nevado, Daniel Ebner, Mohammad Bohlooly-Y, Noel Buckley, Menelas N. Pangalos, Jack Price, Simon Lovestone
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Our understanding of the molecular processes underlying Alzheimer’s disease (AD) is still limited, hindering the development of effective treatments, and highlighting the need for human-specific models. Advances in identifying components of the amy
Externí odkaz:
https://doaj.org/article/cbd88ea3b15f4424a992edf8c0d98186
Autor:
Ece Kocagoncu, Kanisa Arunasalam, Jennifer Lawson, Ivan Koychev, Paresh Malhotra, James B. Rowe, Tharani Chessell, Emma Mee Hayes, Zameel M. Cader, Richard Wade-Martins, Basil H. Ridha, Elena M. Ribe, Bryan Ng, Tina Wei, Noel J. Buckley, Helen Rowland, Anne Hedegaard, Alan J. Thomas, Roger N. Gunn, Dominic Ffytche, Dennis Chan, Giovanna Zamboni, Simon Lovestone
Establishing preclinical models of Alzheimer’s disease that predict clinical outcomes remains a critically important, yet to date not fully realised, goal. Models derived from human cells offer considerable advantages over non-human models, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a843909c7338de3e23ecd1b56df8fa9
https://doi.org/10.1101/2021.11.09.467891
https://doi.org/10.1101/2021.11.09.467891
Autor:
Lara Nonell, Elena M. Ribe, Janet Piñero, Olga Valverde, Laura I. Furlong, Simon Lovestone, Alejo J. Nevado-Holgado, Ana Martín-Sánchez, Ferran Sanz, Magdalena Arnal
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2021)
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2021)
Background: Major depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer's disease (AD). Despite both diseases having a robust genetic component, the common transcriptomic sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2e00f1e3bc503c17e5b9c4c11773b5
http://hdl.handle.net/10230/47344
http://hdl.handle.net/10230/47344
Autor:
Alejo J. Nevado Holgado, Lara Nonell, Laura I. Furlong, Magdalena Arnal, Ana Martín-Sánchez, Ferran Sanz, Janet Piñero, Olga Valverde, Elena M. Ribe, Simon Lovestone
Major Depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer’s disease (AD). Despite both diseases having a robust genetic component, the common transcriptomic signature rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40bf9d66def29835b0f97840541bca4
https://doi.org/10.1101/2020.07.31.231159
https://doi.org/10.1101/2020.07.31.231159
Autor:
Simon Lovestone, Lars Bertram, Ruth Frikke-Schmidt, Patrizia Mecocci, Jill C. Richardson, Giovanni B. Frisoni, Fabian Kilpert, B. Paul Morgan, Abdul Hye, Stephanie J.B. Vos, Olivier Blin, Valerija Dobricic, Silvy Gabel, Richard Dobson, Mikel Tainta, Shengjun Hong, Frederik Barkhof, Cristina Legido-Quigley, Frans R.J. Verhey, Liu Shi, Børge G. Nordestgaard, Katrine L. Rasmussen, Pablo Martinez-Lage, Alejo J. Nevado-Holgado, Steven J. Kiddle, Charlotte E. Teunissen, Iwona Kłoszewska, Nicholas J. Ashton, Sebastiaan Engelborghs, Noel J. Buckley, Antonio Cuadrado, Petronella Kettunen, Bruno Vellas, José Luis Molinuevo, Kristel Sleegers, Alison L. Baird, Isabelle Bos, Angharad R. Morgan, Pieter Jelle Visser, Martina Sattlecker, Benjamine Y Liu, Mara ten Kate, Daniel Alcolea, Alberto Lleó, Ellen Elisa De Roeck, Lorena Rami, Elena M. Ribe, Andre Franke, Rik Vandenberghe, Julius Popp, Sarah Westwood, Régis Bordet, Magda Tsolaki, Yvonne Freund-Levi, Kaj Blennow, Philip Scheltens, Sune F. Nielsen, Gwendoline Peyratout, Peter Johannsen, Henrik Zetterberg, Hilkka Soininen, Johannes Streffer, Lutz Frölich, Karen Meersmans, Laura Winchester, Anders Wallin, Richard Killick
Publikováno v:
Shi, L, Winchester, L M, Liu, B Y, Killick, R, Ribe, E M, Westwood, S, Baird, A L, Buckley, N J, Hong, S, Dobricic, V, Kilpert, F, Franke, A, Kiddle, S, Sattlecker, M, Dobson, R, Cuadrado, A, Hye, A, Ashton, N J, Morgan, A R, Bos, I, Vos, S J B, Ten Kate, M, Scheltens, P, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, De Roeck, E E, Sleegers, K, Frisoni, G B, Blin, O, Richardson, J C, Bordet, R, Molinuevo, J L, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lleó, A, Alcolea, D, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Teunissen, C E, Freund-Levi, Y, Frölich, L, Legido-Quigley, C, Barkhof, F, Blennow, K, Rasmussen, K L, Nordestgaard, B G, Frikke-Schmidt, R, Nielsen, S F, Soininen, H, Vellas, B, Kloszewska, I, Mecocci, P, Zetterberg, H, Morgan, B P, Streffer, J, Visser, P J, Bertram, L, Nevado-Holgado, A J & Lovestone, S 2020, ' Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 77, no. 3, pp. 1353-1368 . https://doi.org/10.3233/JAD-200208
Journal of Alzheimer's Disease
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Alzheimer's Disease, 77(3), 1353-1368. IOS Press
Shi, L, Winchester, L M, Liu, B Y, Killick, R, Ribe, E M, Westwood, S, Baird, A L, Buckley, N J, Hong, S, Dobricic, V, Kilpert, F, Franke, A, Kiddle, S, Sattlecker, M, Dobson, R, Cuadrado, A, Hye, A, Ashton, N J, Morgan, A R, Bos, I, Vos, S J B, ten Kate, M, Scheltens, P, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, de Roeck, E E, Sleegers, K, Frisoni, G B, Blin, O, Richardson, J C, Bordet, R G, Molinuevo, J L, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lleó, A, Alcolea, D, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Teunissen, C E, Freund-Levi, Y, Frölich, L, Legido-Quigley, C, Barkhof, F, Blennow, K, Rasmussen, K L, Nordestgaard, B R G, Frikke-Schmidt, R, Nielsen, S F, Soininen, H, Vellas, B, Kloszewska, I, Mecocci, P, Zetterberg, H, Morgan, B P, Streffer, J, Visser, P J, Bertram, L, Nevado-Holgado, A J & Lovestone, S 2020, ' Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 77, no. 3, pp. 1353-1368 . https://doi.org/10.3233/JAD-200208
Journal of Alzheimer's disease
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Alzheimer's Disease, IOS Press, 2020, 77 (3), pp.1353-1368. ⟨10.3233/JAD-200208⟩
JOURNAL OF ALZHEIMERS DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Journal of Alzheimer's disease, vol. 77, no. 3, pp. 1353-1368
Journal of Alzheimer's Disease
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Alzheimer's Disease, 77(3), 1353-1368. IOS Press
Shi, L, Winchester, L M, Liu, B Y, Killick, R, Ribe, E M, Westwood, S, Baird, A L, Buckley, N J, Hong, S, Dobricic, V, Kilpert, F, Franke, A, Kiddle, S, Sattlecker, M, Dobson, R, Cuadrado, A, Hye, A, Ashton, N J, Morgan, A R, Bos, I, Vos, S J B, ten Kate, M, Scheltens, P, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, de Roeck, E E, Sleegers, K, Frisoni, G B, Blin, O, Richardson, J C, Bordet, R G, Molinuevo, J L, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lleó, A, Alcolea, D, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Teunissen, C E, Freund-Levi, Y, Frölich, L, Legido-Quigley, C, Barkhof, F, Blennow, K, Rasmussen, K L, Nordestgaard, B R G, Frikke-Schmidt, R, Nielsen, S F, Soininen, H, Vellas, B, Kloszewska, I, Mecocci, P, Zetterberg, H, Morgan, B P, Streffer, J, Visser, P J, Bertram, L, Nevado-Holgado, A J & Lovestone, S 2020, ' Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology ', Journal of Alzheimer's Disease, vol. 77, no. 3, pp. 1353-1368 . https://doi.org/10.3233/JAD-200208
Journal of Alzheimer's disease
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Alzheimer's Disease, IOS Press, 2020, 77 (3), pp.1353-1368. ⟨10.3233/JAD-200208⟩
JOURNAL OF ALZHEIMERS DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Journal of Alzheimer's disease, vol. 77, no. 3, pp. 1353-1368
© 2020 – IOS Press and the authors.
[Background]: Previous studies suggest that Dickkopf-1 (DKK1), an inhibitor of Wnt signaling, plays a role in amyloid-induced toxicity and hence Alzheimer’s disease (AD). However, the effect of DKK1 expre
[Background]: Previous studies suggest that Dickkopf-1 (DKK1), an inhibitor of Wnt signaling, plays a role in amyloid-induced toxicity and hence Alzheimer’s disease (AD). However, the effect of DKK1 expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece2f91b560d753f2bdb4e65d088a1d5
https://curis.ku.dk/ws/files/255888917/jad_2020_77_3_jad_77_3_jad200208_jad_77_jad200208.pdf
https://curis.ku.dk/ws/files/255888917/jad_2020_77_3_jad_77_3_jad200208_jad_77_jad200208.pdf
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16991 (2011)
Impaired insulin signalling is increasingly thought to contribute to Alzheimer's disease (AD). The ε4 isoform of the APOE gene is the greatest genetic risk factor for sporadic, late onset AD, and is also associated with risk for type 2 diabetes mell
Externí odkaz:
https://doaj.org/article/f07aeb8cb7d248069530e26bba939a50
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience
Frontiers in Neuroscience
Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in several physiological and pathological states, including Alzheimer's disease (AD). With a prominent extracellular chaperone function, additional roles have been dis