Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elena M. Egorina"'
Autor:
Dusten Unruh, Vladimir Y. Bogdanov, John-Bjarne Hansen, Timofey Sovershaev, Mikhail A. Sovershaev, Elena M. Egorina
Publikováno v:
Thrombosis Research. 135:398-403
Background Bone morphogenetic protein (BMP)-7, a major regulator of bone metabolism, inhibits ectopic calcification in atherosclerotic plaques. We have recently reported that BMP-7 is also a potent inducer of tissue factor (TF) in human mononuclear c
Publikováno v:
Blood Coagulation & Fibrinolysis. 23:345-350
Varying specificity of anti-tissue factor (anti-TF) antibodies gives rise to erroneous conclusions on TF positivity of platelets. Although monocytes are a well established source of TF in whole blood, there is no consensus whether platelets express o
Autor:
Ellisiv B. Mathiesen, Mikhail A. Sovershaev, Vladimir Y. Bogdanov, Manjunath Goolyam Basavaraj, John-Bjarne Hansen, John T. Fallon, Franz Gruber, Bjarne Østerud, Elena M. Egorina
Publikováno v:
Thrombosis Research. 129:e134-e141
Background Thrombogenicity of atherosclerotic plaque largely depends on plaque morphology and their content of tissue factor (TF) and tissue factor pathway inhibitor (TFPI). The relationship between morphological composition of plaque (lipid-rich or
Autor:
John-Bjarne Hansen, Bjarne Østerud, Timofey Sovershaev, Vladimir Y. Bogdanov, John T. Fallon, Mikhail A. Sovershaev, Elena M. Egorina, Natalia Seredkina
Publikováno v:
Blood Coagulation & Fibrinolysis. 22:642-650
Morphology of atherosclerotic plaque is a major determinant of plaque thrombogenicity. Calcified atherosclerotic lesions are less prone to thrombosis and contain less tissue factor (TF) than lipid-rich plaques. Although bone morphogenetic protein (BM
Autor:
Johannes-Peter Stasch, Bjarne Østerud, Pal Pacher, John-Bjarne Hansen, Oleg V. Evgenov, Mikhail A. Sovershaev, Elena M. Egorina
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1578-1586
Objective— Tissue factor (TF), a major initiator of blood coagulation, contributes to inflammation, atherosclerosis, angiogenesis, and vascular remodeling. Pharmacological agonists of soluble guanylate cyclase (sGC) attenuate systemic and pulmonary
Autor:
H. Devold, John-Bjarne Hansen, Elena M. Egorina, Trond Ø. Jørgensen, Mikhail A. Sovershaev, Karianne Fredenfeldt Lind, Bjarne Østerud
Publikováno v:
Journal of Thrombosis and Haemostasis. 6:1742-1749
Summary. Background: To date, there is no unequivocal opinion on whether human eosinophils express tissue factor (TF). Therefore, we studied the expression of TF protein and activity in resting or stimulated immunologically purified human eosinophils
Publikováno v:
Blood. 111:1208-1216
Unlike unanimous opinion on tissue factor (TF) expression in monocytes, the quest for TF presence in granulocytes has been going on for decades. To study the cell origin and track the blood-borne TF, we assessed TF activity and protein levels, knocke
Publikováno v:
Journal of Thrombosis and Haemostasis. 5:2453-2460
Summary. Background: The high and low responder phenomenon describes an intersubject variability in mononuclear cell (MNC) prothrombotic reactivity to lipopolysaccharide (LPS) stimulation. Because alterations in surface CD36 expression in monocytes w
Publikováno v:
Journal of Thrombosis and Haemostasis. 4:614-620
Summary. Background: Tissue factor (TF) is an integral membrane protein essential for the initiation of the extrinsic pathway of hemostasis. A precise understanding of the TF regulation is still limited and dependent on the availability of methodolog
Autor:
Behnaz Parhami-Seren, Kenneth G. Mann, Jan Ole Olsen, Bjarne Østerud, Geir Bjørkøy, Mikhail A. Sovershaev, Franz Gruber, Elena M. Egorina
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1493-1498
Objective— The high and low responder phenomenon describes individual differences in lipopolysaccharide (LPS)-induced monocyte tissue factor (TF) activity. We characterized patterns of intracellular accumulation, externalization, and shedding of TF