Výsledky vyhledávání - "Elena M Perkins"

Bubble bilevel ventilation facilitates gas exchange in anesthetized rabbits

Autor: Sunil P John, Stephen C John, Benjamin D Carr, Peter A. Gustafson, Joseph T Church, Anna V John, Macdonald Dick, Elena M Perkins, Azmath Mohammed, Susan M Smith, Jennifer S McLeod, J Hudson Barnett

Publikováno v: Pediatric Research

Background Bubble continuous positive airway pressure is an established therapy for infants in respiratory distress. In resource-limited settings, few treatment options exist for infants requiring further respiratory support. A bubble bilevel device

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0817d4d468b5c60e46c5238d78101e
https://doi.org/10.1038/s41390-020-0928-0

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The artificial placenta: Continued lung development during extracorporeal support in a preterm lamb model

Autor: J. Kelley Bentley, Robert H. Bartlett, Hayley R. Hoffman, John D.E. Barks, Megan A. Coughlin, Joseph T. Church, Elena M. Perkins, Marc B. Hershenson, Raja Rabah, George B. Mychaliska

Publikováno v: Journal of Pediatric Surgery. 53:1896-1903

Purpose An artificial placenta (AP) utilizing extracorporeal life support (ECLS) could avoid the harm of mechanical ventilation (MV) while allowing the lungs to develop. Methods AP lambs (n = 5) were delivered at 118 days gestational age (GA; term =

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e57a38e40caa8fd6730abae3adfa7f
https://doi.org/10.1016/j.jpedsurg.2018.06.001

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Normothermic Ex Vivo Heart Perfusion: Effects of Live Animal Blood and Plasma Cross Circulation

Autor: Kristopher B. Deatrick, Fares Alghanem, Gabe E. Owens, Martin L. Bocks, Elena M. Perkins, Joseph T. Church, Robert H. Bartlett, John M. Trahanas, Joseph Phillips, Alvaro Rojas-Pena, Min Hee Song

Publikováno v: ASAIO Journal. 63:766-773

Prolonged normothermic ex vivo heart perfusion could transform cardiac transplantation. To help identify perfusate components that might enable long-term perfusion, we evaluated the effects of cross-circulated whole blood and cross-circulated plasma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34327f0c88a07fed944261ff8b1cb293
https://doi.org/10.1097/mat.0000000000000583

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Splenic development and injury in premature lambs supported by the artificial placenta

Autor: Robert H. Bartlett, Raja Rabah, Jennifer S. McLeod, Pavel Hala, Ellery Sarosi, Megan A. Coughlin, Joseph T. Church, Elena M. Perkins, Matias Caceres Quinones, Benjamin D. Carr, Alvaro Rojas-Pena, Clinton J Poling, Elizabeth Freiheit, George B. Mychaliska

Publikováno v: J Pediatr Surg

The purpose of this study is to evaluate splenic effects during artificial placenta (AP) support.AP lambs (118-121 d, n = 14) were delivered and placed on the AP support for a goal of 10-14 days. Cannulation used right jugular drainage and umbilical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206af8d978cacf164f3f55c262fef6bb
https://pubmed.ncbi.nlm.nih.gov/30902457

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An Artificial Placenta Protects Against Lung Injury and Promotes Continued Lung Development in Extremely Premature Lambs

Autor: Raja Rabah, Robert H. Bartlett, Benjamin S. Bryner, Marc B. Hershenson, John D.E. Barks, Nicole L. Werner, George B. Mychaliska, Megan A. Coughlin, Joseph T. Church, Elena M. Perkins, J. K. Bentley

Publikováno v: ASAIO journal (American Society for Artificial Internal Organs : 1992). 65(7)

An artificial placenta (AP) utilizing extracorporeal life support (ECLS) could protect premature lungs from injury and promote continued development. Preterm lambs at estimated gestational age (EGA) 114-128 days (term = 145) were delivered by Caesari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48ebafc080c73a47799ed9f25c50201
https://pubmed.ncbi.nlm.nih.gov/30585874

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An Early Investigation into Possible Alternatives to Stapled Hysterotomy in Open Fetal Surgery

Autor: Erin E. Perrone, George B. Mychaliska, Ingrid L. Bergin, Marjorie C. Treadwell, Alvaro Rojas-Pena, Mark Bilger, Megan A. Coughlin, Joseph T. Church, Jennifer S. McLeod, Deborah R. Berman, Hayley R. Hoffman, Marcus D. Jarboe, Elena M. Perkins

Publikováno v: American journal of perinatology. 36(7)

Purpose We hypothesized that surgical energy could be used to create hysterotomies in open fetal surgery. Study Design Initial studies compared the LigaSure Impact and Harmonic ACE + 7 Shears in the efficiency of hysterotomy and thermal damage. Pregn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6589da58984f68e50f0578468ae39057
https://pubmed.ncbi.nlm.nih.gov/30372770

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Gastrointestinal Mucosal Development and Injury in Premature Lambs Supported by the Artificial Placenta

Autor: Raja Rabah, Megan A. Coughlin, Joseph T. Church, Prathusha Yerramilli, George B. Mychaliska, Joel K. Greenson, Jennifer S. McLeod, Erin E. Perrone, Elena M. Perkins, Robert H. Bartlett, Alvaro Rojas-Pena

BACKGROUND: An Artificial Placenta (AP) utilizing extracorporeal life support (ECLS) could revolutionize care of extremely premature newborns, but its effects on gastrointestinal morphology and injury need investigation. METHODS: Lambs (116-121 days

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6795fee9d96ac5c21eaa2caf96093868
https://europepmc.org/articles/PMC5994371/

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Cerebral Oxygenation of Premature Lambs Supported by an Artificial Placenta

Autor: Alvaro Rojas-Pena, Robert H. Bartlett, Ahmed M. El-Sabbagh, Renée A. Shellhaas, Jennifer S. McLeod, George B. Mychaliska, John D.E. Barks, Joseph T. Church, Benjamin S. Bryner, Elena M. Perkins, Brian W. Gray, Sara J. Zakem, Andrew Shaffer

An artificial placenta (AP) using venovenous extracorporeal life support (VV-ECLS) could represent a paradigm shift in the treatment of extremely premature infants. However, AP support could potentially alter cerebral oxygen delivery. We assessed cer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a376fe08e848c2c81baea96237e6f8f
https://europepmc.org/articles/PMC5860928/

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An extracorporeal artificial placenta supports extremely premature lambs for 1week

Autor: John D.E. Barks, Hayley R. Hoffman, George B. Mychaliska, Brian W. Gray, Benjamin S. Bryner, Ryan P. Davis, Alvaro Rojas-Pena, Ronald B. Hirschl, Elena M. Perkins, Robert H. Bartlett, Gabe E. Owens, Martin L. Bocks

Publikováno v: Journal of Pediatric Surgery. 50:44-49

Purpose The treatment of extreme prematurity remains an unsolved problem. We developed an artificial placenta (AP) based on extracorporeal life support (ECLS) that simulates the intrauterine environment and provides gas exchange without mechanical ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::648b8e4a8cdecb4e208df2f6e4b5efde
https://doi.org/10.1016/j.jpedsurg.2014.10.028

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Perfluorocarbons Prevent Lung Injury and Promote Development during Artificial Placenta Support in Extremely Premature Lambs

Autor: Raja Rabah, Katherine Boss, Marc B. Hershenson, J. Kelley Bentley, Megan A. Coughlin, Joseph T. Church, Robert H. Bartlett, Jennifer S. McLeod, Elena M. Perkins, George B. Mychaliska

Publikováno v: Neonatology. 113(4)

Background: Extremely premature neonates suffer high morbidity and mortality. An artificial placenta (AP) using extracorporeal life support (ECLS) is a promising therapy. Objectives: We hypothesized that intratracheal perfluorocarbon (PFC) instillati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baccc5dee691a8b7ea065c7a8bb8a554
https://pubmed.ncbi.nlm.nih.gov/29478055

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