Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Elena Lorente"'
Autor:
Jennifer Redondo-Antón, MG Fontela, Laura Notario, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Elena Lorente, Pilar Lauzurica
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells. CD69 activation kinetics differ by developmental stage, cell linage and activating cond
Externí odkaz:
https://doaj.org/article/01121cb889ed4b1e874d099000e729dc
Autor:
Patricia G. de la Sota, Elena Lorente, Laura Notario, Carmen Mir, Oscar Zaragoza, Daniel López
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1176 (2021)
Human respiratory syncytial virus (HRSV) is the most common cause of severe respiratory infections in infants and young children, often leading to hospitalization. In addition, this virus poses a serious health risk in immunocompromised individuals a
Externí odkaz:
https://doaj.org/article/b9196532f56644809110bb1b6d1a1d9b
Autor:
Elena Lorente, Alejandro Barriga, Eilon Barnea, Concepción Palomo, Juan García-Arriaza, Carmen Mir, Mariano Esteban, Arie Admon, Daniel López
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007547 (2019)
BackgroundEfficient adaptive antiviral cellular and humoral immune responses require previous recognition of viral antigenic peptides bound to human leukocyte antigen (HLA) class I and II molecules, which are exposed on the surface of infected and an
Externí odkaz:
https://doaj.org/article/4f8bc775e33845b491b7265aab1f301a
Autor:
Elena Lorente, Alejandro Barriga, Juan García-Arriaza, François A Lemonnier, Mariano Esteban, Daniel López
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0006036 (2017)
The adaptive cytotoxic T lymphocyte (CTL)-mediated immune response is critical for clearance of many viral infections. These CTL recognize naturally processed short viral antigenic peptides bound to human leukocyte antigen (HLA) class I molecules on
Externí odkaz:
https://doaj.org/article/827532733d334576bc71210c4daee2c2
Autor:
Alejandro Barriga, Elena Lorente, Carolina Johnstone, Carmen Mir, Margarita del Val, Daniel López
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106772 (2014)
CD8(+) T cells identify and kill infected cells through the specific recognition of short viral antigens bound to human major histocompatibility complex (HLA) class I molecules. The colossal number of polymorphisms in HLA molecules makes it essential
Externí odkaz:
https://doaj.org/article/5a5b8c1e23584f618bf183aba679ee3c
Autor:
Elena Lorente, Susana Infantes, Eilon Barnea, Ilan Beer, Alejandro Barriga, Noel García-Medel, Fátima Lasala, Mercedes Jiménez, Arie Admon, Daniel López
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59118 (2013)
The transporter associated with antigen processing (TAP) translocates the cytosol-derived proteolytic peptides to the endoplasmic reticulum lumen where they complex with nascent human leukocyte antigen (HLA) class I molecules. Non-functional TAP comp
Externí odkaz:
https://doaj.org/article/5bbee52d94cf4713bacceff0d4b157d8
Autor:
Elena Lorente, Alejandro Barriga, Carolina Johnstone, Carmen Mir, Mercedes Jiménez, Daniel López
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79596 (2013)
In the classical human leukocyte antigen (HLA) class I antigen processing and presentation pathway, the antigenic peptides are generated from viral proteins by multiple proteolytic cleavages of the proteasome (and in some cases other cytosolic protea
Externí odkaz:
https://doaj.org/article/cb9df604ae234ad89acd76c8985fea37
Autor:
Elisenda Alari-Pahissa, Laura Notario, Elena Lorente, Javier Vega-Ramos, Ana Justel, Daniel López, José A Villadangos, Pilar Lauzurica
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48593 (2012)
CD69 is rapidly upregulated on T cells upon activation. In this work we show that this is also the case for CD69 expression on dendritic cells (DC). Thus, the expression kinetics of CD69 on both cell types is reminiscent of the one of costimulatory m
Externí odkaz:
https://doaj.org/article/8e6badfb08c642c28f59673a03a449c5
Autor:
Elena Lorente, Antonio J. Martín-Galiano, Dganit Melamed Kadosh, Alejandro Barriga, Juan García-Arriaza, Carmen Mir, Mariano Esteban, Arie Admon, Daniel López
Publikováno v:
Journal of Proteome Research. 21:164-171
Adaptive cellular and humoral immune responses to infectious agents require previous recognition of pathogenic peptides bound to human leukocyte antigen (HLA) class II molecules exposed on the surface of the professional antigen-presenting cells. Kno
Autor:
Carmen Mir, Patricia G. de la Sota, Adriana Quijada-Freire, Miguel Marcilla, Elena Lorente, Daniel López
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10503, p 10503 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10503, p 10503 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Volume 22
Issue 19
Identification of a natural human leukocyte antigen (HLA) ligandome is a key element to understand the cellular immune response. Advanced high throughput mass spectrometry analyses identify a relevant, but not complete, fraction of the many tens of t