Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elena Lo Furno"'
Publikováno v:
Genes, Vol 8, Iss 1, p 42 (2017)
Early embryonic cleavages are characterized by short and highly synchronous cell cycles made of alternating S- and M-phases with virtually absent gap phases. In this contracted cell cycle, the duration of DNA synthesis can be extraordinarily short. D
Externí odkaz:
https://doaj.org/article/ed08b98d8c9548f9b4b720ba9d22b593
Autor:
Elena Lo Furno, Isabelle Busseau, Antoine Aze, Claudio Lorenzi, Cima Saghira, Matt C Danzi, Stephan Zuchner, Domenico Maiorano
Publikováno v:
Nucleic Acids Research
In early embryogenesis of fast cleaving embryos, DNA synthesis is short and surveillance mechanisms preserving genome integrity are inefficient, implying the possible generation of mutations. We have analyzed mutagenesis in Xenopus laevis and Drosoph
Publikováno v:
Methods in enzymology. 661
Maintenance and surveillance of genome integrity is crucial during the very early steps of embryonic development, since de novo mutations generated during this stage can be propagated in differentiated adult cells and may lead to predisposition to di
Publikováno v:
Methods in Enzymology ISBN: 9780323907330
Maintenance and surveillance of genome integrity is crucial during the very early steps of embryonic development, since de novo mutations generated during this stage can be propagated in differentiated adult cells and may lead to predisposition to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c341bbb0050521ce0b75ccb0d1fa2f28
https://doi.org/10.1016/bs.mie.2021.08.016
https://doi.org/10.1016/bs.mie.2021.08.016
Publikováno v:
Pluripotent Stem Cells-From the Bench to the Clinic
Maintenance of genomic stability is crucial in ensuring cellular homeostasis and perpetuation of life. Perpetuation of the genetic information relies upon faithful replication of the genome. Mutations, generated during DNA synthesis and/or cell divis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114a7c972f1586283a658db9a577b052
http://www.intechopen.com/articles/show/title/genomic-instability-of-pluripotent-stem-cells-origin-and-consequences
http://www.intechopen.com/articles/show/title/genomic-instability-of-pluripotent-stem-cells-origin-and-consequences