Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elena Kuhfeldt"'
Publikováno v:
Journal of Medicinal Chemistry. 65:10588-10610
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c6f09daca944d39060283871ca764d
https://doi.org/10.1021/acs.jmedchem.2c00765
https://doi.org/10.1021/acs.jmedchem.2c00765
Autor:
Horst, Prescher, Astrid, Schweizer, Martin, Frank, Elena, Kuhfeldt, Julia, Ring, Lars, Nitschke
Publikováno v:
Journal of medicinal chemistry. 65(15)
Significant interest in the development of high-affinity ligands for Siglecs exists due to the various therapeutically relevant functions of these proteins. Here, we report a new strategy to develop and design Siglec ligands as disialyl-oligosacchari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7751f82e7a9a561894679d7c26762d5
https://pubmed.ncbi.nlm.nih.gov/35881556
https://pubmed.ncbi.nlm.nih.gov/35881556
Publikováno v:
ChemBioChem. 18:1216-1225
CD22 is a member of the Siglec family. Considerable attention has been drawn to the design and synthesis of new Siglec ligands to explore target biology and innovative therapies. In particular, CD22-ligand-targeted nanoparticles with therapeutic func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9b56e1886f78836bdf4024f4a61e02
https://doi.org/10.1002/cbic.201600707
https://doi.org/10.1002/cbic.201600707
Autor:
Carsten Watzl, Reinhard Brossmer, Horst Prescher, Stephan Gütgemann, Elena Kuhfeldt, Lars Nitschke, Martin Frank, Astrid Schweizer
Publikováno v:
Journal of medicinal chemistry. 60(3)
Natural killer cells are able to directly lyse tumor cells, thereby participating in the immune surveillance against cancer. Unfortunately, many cancer cells use immune evasion strategies to avoid their eradication by the immune system. A prominent e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2e2c0bb7aaecf39c4bda17c13c97dc
https://pubmed.ncbi.nlm.nih.gov/28103033
https://pubmed.ncbi.nlm.nih.gov/28103033
Autor:
Reinhard Brossmer, Stephan Gütgemann, Carsten Watzl, Horst Prescher, Elena Kuhfeldt, Martin Frank
Publikováno v:
Bioorganicmedicinal chemistry. 23(17)
Siglecs (sialic acid recognizing immunoglobulin like lectins) are a family of lectins with specificity for sialic acid containing carbohydrates. Synthetic sialic acid derivatives with high affinity proved useful to unravel the biological role of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95bbdc5274c235d335540c77ce3af8b
https://pubmed.ncbi.nlm.nih.gov/26234906
https://pubmed.ncbi.nlm.nih.gov/26234906