Výsledky vyhledávání - "Elena Kaschina"

Akademický článek

Aortic Aneurysm: Finding the Right Target

Autor: Elena Kaschina

Publikováno v: Biomedicines, Vol 11, Iss 5, p 1345 (2023)

This Special Issue of Biomedicines highlights many important scientific findings in aneurysm research [...]

Externí odkaz: https://doaj.org/article/8ea53c87d86042c59965610ea7ccc52d

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Akademický článek

The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity

Autor: Marion Peyrou, Rubén Cereijo, Tania Quesada-López, Laura Campderrós, Aleix Gavaldà-Navarro, Laura Liñares-Pose, Elena Kaschina, Thomas Unger, Miguel López, Marta Giralt, Francesc Villarroya

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provi

Externí odkaz: https://doaj.org/article/150ca23506ff4dd1a06c23947991322f

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Akademický článek

Differential Regulation of MMPs, Apoptosis and Cell Proliferation by the Cannabinoid Receptors CB1 and CB2 in Vascular Smooth Muscle Cells and Cardiac Myocytes

Autor: Bettina Greiner, Manuela Sommerfeld, Ulrich Kintscher, Thomas Unger, Kai Kappert, Elena Kaschina

Publikováno v: Biomedicines, Vol 10, Iss 12, p 3271 (2022)

Cannabinoids (CB) are implicated in cardiovascular diseases via the two main receptor subtypes CB1R and CB2R. This study investigated whether cannabinoids regulate the activity of matrix metalloproteases (MMP-2, MMP-9) in vascular smooth muscle cells

Externí odkaz: https://doaj.org/article/29b7ba1c843a40d5b7d2263122354b23

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Akademický článek

P.29 Involvement of Cannabinoid Receptors in Regulation of MMPs, Cell Proliferation and Apoptosis in Vascular Smooth Muscle Cells

Autor: Bettina Greiner, Manuela Sommerfeld, Ulrich Kintscher, Kai Kappert, Elena Kaschina

Publikováno v: Artery Research, Vol 26, Iss Supplement 1 (2020)

Objectives: Cannabinoid receptors CB1R and CB2R are expressed in the vascular smooth muscle cells (VSMCs) and may contribute to vascular remodeling process (O’Sullivan, 2015). This study aimed to investigate the implication of CB1R and CB2R in the

Externí odkaz: https://doaj.org/article/4ddc85c395224abaa45d4fd092827384

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Akademický článek

Use of MALDI Mass Spectrometry Imaging to Identify Proteomic Signatures in Aortic Aneurysms after Endovascular Repair

Autor: Matthias Buerger, Oliver Klein, Sebastian Kapahnke, Verena Mueller, Jan Paul Frese, Safwan Omran, Andreas Greiner, Manuela Sommerfeld, Elena Kaschina, Anett Jannasch, Claudia Dittfeld, Adrian Mahlmann, Irene Hinterseher

Publikováno v: Biomedicines, Vol 9, Iss 9, p 1088 (2021)

Endovascular repair (EVAR) has become the standard procedure in treating thoracic (TAA) or abdominal aortic aneurysms (AAA). Not entirely free of complications, a persisting perfusion of the aneurysm after EVAR, called Endoleak (EL), leads to reinter

Externí odkaz: https://doaj.org/article/cae08985a1d7423596d2eb7b24c76114

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Akademický článek

P6 ANGIOTENSIN AT2 RECEPTOR AGONIST, COMPOUND 21, MAINTAINS VASCULAR INTEGRITY AND PREVENTS ABDOMINAL AORTIC ANEURYSM PROGRESSION IN THE RAT

Autor: Christoph Lange, Manuela Sommerfeld, Pawel Namsolleck, Ulrich Kintscher, Thomas Unger, Elena Kaschina

Publikováno v: Artery Research, Vol 20 (2017)

The effects of the selective angiotensin AT2 receptor agonist, compound 21 (C21), on abdominal aortic aneurysm (AAA) formation were investigated in normotensive Wistar rats. AAA was induced by perfusion of isolated aortic segments with elastase (Ani

Externí odkaz: https://doaj.org/article/4ff1cce41ade45d3bb3514ff34e51cf9

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