Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Elena Kalinichenko"'
1
Akademický článek
Novel Phthalic-Based Anticancer Tyrosine Kinase Inhibitors: Design, Synthesis and Biological Activity
Autor: Elena Kalinichenko, Aliaksandr Faryna, Tatyana Bozhok, Anna Golyakovich, Alesya Panibrat
Publikováno v: Current Issues in Molecular Biology, Vol 45, Iss 3, Pp 1820-1842 (2023)
In this work, fragments of isophthalic and terephthalic acids are proposed as a structural scaffold to develop potential inhibitors of protein kinases. Novel isophthalic and terephthalic acid derivatives were designed as type-2 protein kinase inhibit
Externí odkaz: https://doaj.org/article/06769da3ed5740068bb2a883e94d8ed0
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2
Akademický článek
Synthesis, Biological Activities and Docking Studies of Novel 4-(Arylaminomethyl)benzamide Derivatives as Potential Tyrosine Kinase Inhibitors
Autor: Elena Kalinichenko, Aliaksandr Faryna, Viktoria Kondrateva, Alena Vlasova, Valentina Shevchenko, Alla Melnik, Olga Avdoshko, Alla Belko
Publikováno v: Molecules, Vol 24, Iss 19, p 3543 (2019)
A number of new compounds containing the 4-(aminomethyl)benzamide fragment as a linker were designed and synthesized, and their biological activities were evaluated as potential anticancer agents. The cytotoxicity activity of the designed compounds w
Externí odkaz: https://doaj.org/article/148f4dfd874a4c9ba2cf819ece4d20a5
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3
N1-(3-(Trifluoromethyl)Phenyl) Isophthalamide Derivatives as Promising Inhibitors of Vascular Endothelial Growth Factor Receptor: Pharmacophore-Based Design, Docking, and MM-PBSA/MM-GBSA Binding Energy Estimation
Autor: Aliaksandr, Faryna, Elena, Kalinichenko
Publikováno v: Biomedical Engineering ISBN: 9781803564678
Molecular Docking-Recent Advances
Targeting protein kinases is a common approach for cancer treatment. In this study, a series of novel terephthalic and isophthalic derivatives were constructed as potential type 2 protein kinase inhibitors adapting pharmacophore features of approved
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695e34864e57127f239e976635424cf9
https://doi.org/10.5772/intechopen.107236
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4
Modified (2′,5′)Oligonucleotides: The Influence of Structural and Steriochemical Factors on Biological and Immunotropic Activity
Autor: Elena Kalinichenko
Publikováno v: Oligonucleotides-Overview and Applications
Oligonucleotides-Overview and Applications ISBN: 9781803556277
The synthesis of a large number of analogs of natural 2-5A and the results of studies to clarify the relationship between the structure and spatial organization (stereochemistry) and the biological properties of analogs 2-5A have convincingly demonst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cd67dd39983abcf9c1b321591c3ad1
https://mts.intechopen.com/articles/show/title/modified-2-5-oligonucleotides-the-influence-of-structural-and-steriochemical-factors-on-biological-a
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6
Improvement of the method of drilling and blasting operations at the use of explosive substance «Ukrainite» in underground mining works
Autor: Elena Kalinichenko, Serhii Pysmennyi, M Stupnik, Mykhailo Fedko, Vsevolod Kalinichenko, Boris Rymarchuk
Publikováno v: Tehnologìčnij Audit ta Rezervi Virobnictva, Vol 6, Iss 1(44), Pp 29-35 (2018)
The object of research is a rock massif of iron ore, which is destroyed by an explosive located in deep wells. One of the most problematic places is ensuring uniform grinding of the rock massif during underground mining of mineral deposits at great d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b216cd5f30c3175d48a1ab406712a4
http://journals.uran.ua/tarp/article/view/152055
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