Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Elena Jazin"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Sex differences in the developing human brain are primarily attributed to hormonal influence. Recently however, genetic differences and their impact on the developing nervous system have attracted increased attention. To understand genetically driven
Externí odkaz:
https://doaj.org/article/45142324fe934fd2858bb239a48d3a79
Autor:
Ann-Sofie Sundman, Fábio Pértille, Luiz Lehmann Coutinho, Elena Jazin, Carlos Guerrero-Bosagna, Per Jensen
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240787 (2020)
Epigenetic factors such as DNA methylation act as mediators in the interaction between genome and environment. Variation in the epigenome can both affect phenotype and be inherited, and epigenetics has been suggested to be an important factor in the
Externí odkaz:
https://doaj.org/article/f5b964e82576449e9b38840ed12326eb
Autor:
Martin M. Johansson, Philipp Pottmeier, Pascalina Suciu, Tauseef Ahmad, Ammar Zaghlool, Jonatan Halvardson, Elisabeth Darj, Lars Feuk, Christiane Peuckert, Elena Jazin
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Global microarray gene expression analyses previously demonstrated differences in female and male embryos during neurodevelopment. In particular, before sexual maturation of the gonads, the differences seem to concentrate on the expression of genes e
Externí odkaz:
https://doaj.org/article/a5e2fb89068844bc81cf1644ab815bce
Autor:
Katarzyna J Radomska, Jonathan Sager, Bryn Farnsworth, Åsa Tellgren-Roth, Giulia Tuveri, Christiane Peuckert, Petronella Kettunen, Elena Jazin, Lina S Emilsson
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146155 (2016)
Quaking (QKI) is an RNA-binding protein involved in post-transcriptional mRNA processing. This gene is found to be associated with several human neurological disorders. Early expression of QKI proteins in the developing mouse neuroepithelium, togethe
Externí odkaz:
https://doaj.org/article/a25c22e1e9a44d218b7e661686cd5128
Autor:
Martin M Johansson, Anneleen Van Geystelen, Maarten H D Larmuseau, Srdjan Djurovic, Ole A Andreassen, Ingrid Agartz, Elena Jazin
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0137223 (2015)
The human Y chromosome is almost always excluded from genome-wide investigations of copy number variants (CNVs) due to its highly repetitive structure. This chromosome should not be forgotten, not only for its well-known relevance in male fertility,
Externí odkaz:
https://doaj.org/article/625869c5181f46f0b90fe828f3d7c8f5
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13079 (2010)
The human QKI gene, called quaking homolog, KH domain RNA binding (mouse), is a candidate gene for schizophrenia encoding an RNA-binding protein. This gene was shown to be essential for myelination in oligodendrocytes. QKI is also highly expressed in
Externí odkaz:
https://doaj.org/article/5731ee0d823345e5a308daa7c60dc01a
Autor:
Björn Reinius, Peter Saetre, Jennifer A Leonard, Ran Blekhman, Roxana Merino-Martinez, Yoav Gilad, Elena Jazin
Publikováno v:
PLoS Genetics, Vol 4, Iss 6, p e1000100 (2008)
The question of a potential biological sexual signature in the human brain is a heavily disputed subject. In order to provide further insight into this issue, we used an evolutionary approach to identify genes with sex differences in brain expression
Externí odkaz:
https://doaj.org/article/b2d96a6c54e84b7aa6e9e9331da8ca67
Publikováno v:
Stem cells and development. 29(23)
Human neural stem cells (hNSCs) have long been used as an in vitro model to study neurogenesis and as candidates for nervous system therapy. Many parameters have been considered when evaluating the success of transplantation, but sex of donor and rec
Autor:
Bryn Farnsworth, Katarzyna J. Radomska, Bettina M. Zimmermann, Elena Jazin, Petronella Kettunen, Lina Emilsson
Publikováno v:
Brain research. 1669
Schizophrenia is a highly heritable disorder with a heterogeneous symptomatology. Research increasingly indicates the importance of the crucial and often overlooked glial perturbations within schizophrenia. Within this study, we examined an isoform o
Autor:
Åsa Tellgren-Roth, Petronella Kettunen, Giulia Tuveri, Lina Emilsson, Katarzyna J. Radomska, Elena Jazin, Jonathan Sager, Bryn Farnsworth, Christiane Peuckert
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146155 (2016)
PLoS ONE
PLoS ONE
Quaking (QKI) is an RNA-binding protein involved in post-transcriptional mRNA processing. This gene is found to be associated with several human neurological disorders. Early expression of QKI proteins in the developing mouse neuroepithelium, togethe