Výsledky vyhledávání - "Elena J. Kumm"

Akademický článek

The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets

Autor: Elena J. Kumm, Oliver Pagel, Stepan Gambaryan, Ulrich Walter, René P. Zahedi, Albert Smolenski, Kerstin Jurk

Publikováno v: Cells, Vol 9, Iss 2, p 472 (2020)

The cell cycle is controlled by microtubule-associated serine/threonine kinase-like (MASTL), which phosphorylates the cAMP-regulated phosphoproteins 19 (ARPP19) at S62 and 19e/α-endosulfine (ENSA) at S67and converts them into protein phosphatase 2A

Externí odkaz: https://doaj.org/article/5586b17b8ff842898b52152756783639

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Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

Autor: Niklas Zimmer, Sophia Zimmer, Stephan Grabbe, Franziska K. Krebs, Carmen Loquai, Kerstin Jurk, Elena J. Kumm, Heidrun Mitzel-Rink, Andrea Tuettenberg

Publikováno v: Cancers, Vol 12, Iss 3653, p 3653 (2020)
Cancers
Volume 12
Issue 12

Platelets have been recently described as an important component of the innate and adaptive immunity through their interaction with immune cells. However, information on the platelet&ndash
T cell interaction in immune-mediated diseases remains l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e44987f1017abce9ba9e811483cc4a
https://www.mdpi.com/2072-6694/12/12/3653

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The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets

Autor: Elena J. Kumm, Stephanie Makhoul, Ulrich Walter, Pengyu Zhang, Kerstin Jurk

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 23

Distinct membrane receptors activate platelets by Src-family-kinase (SFK)-, immunoreceptor-tyrosine-based-activation-motif (ITAM)-dependent stimulation of spleen tyrosine kinase (Syk). Recently, we reported that platelet activation via glycoprotein (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390eb023cb969e7d5913767ad7a23fd9

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Impaired Platelet Function in Sept8-Deficient Mice In Vitro

Autor: Kerstin Jurk, Barbara Zieger, Victoria Petermann, Elena J. Kumm, Katharina Neubauer

Publikováno v: Thrombosis and haemostasis. 121(4)

Septins (Septs) are a widely expressed protein family of 13 mammalian members, recognized as a unique component of the cytoskeleton. In human platelets, we previously described that SEPT4 and SEPT8 are localized surrounding α-granules and move to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61596f77a48a2f0484c9679a58e2575
https://pubmed.ncbi.nlm.nih.gov/33202444

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