Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Elena I. Varlinskaya"'
Autor:
Andrew S. Vore, Paige Marsland, Thaddeus M. Barney, Elena I. Varlinskaya, Justine D. Landin, Kati L. Healey, Sandra Kibble, H. S. Swartzwelder, Lawrence J. Chandler, Terrence Deak
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Early initiation of alcohol use during adolescence, and adolescent binge drinking are risk factors for the development of alcohol use disorder later in life. Adolescence is a time of rapid sex-dependent neural, physiological, and behavioral changes a
Externí odkaz:
https://doaj.org/article/bae836a2ba314bde8367772b01c5fe56
Publikováno v:
Cells, Vol 12, Iss 15, p 1991 (2023)
Alcohol use during adolescence is a serious public health problem, with binge drinking and high-intensity drinking being particularly harmful to the developing adolescent brain. To investigate the adverse consequences of binge drinking and high-inten
Externí odkaz:
https://doaj.org/article/a177edcd90f44573b0e010da35ba956a
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Adolescence is a sensitive developmental period during which alcohol use is often initiated and consumed in high quantities, often at binge or even high-intensity drinking levels. Our lab has repeatedly found that adolescent intermittent ethanol (AIE
Externí odkaz:
https://doaj.org/article/ab82e3c8b91b419fae0b5b913c437ae7
Autor:
Trevor T. Towner, Elena I. Varlinskaya
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Adolescence is a developmental period associated with rapid age-specific physiological, neural, and hormonal changes. Behaviorally, human adolescents are characterized by age-typical increases in novelty-seeking and risk-taking, including the frequen
Externí odkaz:
https://doaj.org/article/452633051675477ab65e0a0f00a0c6c4
Publikováno v:
Neurobiology of Stress, Vol 9, Iss , Pp 124-132 (2018)
The dynorphin/kappa opioid receptor (DYN/KOR) system has been identified as a primary target of stress due to behavioral effects, such as dysphoria, aversion, and anxiety-like alterations that result from activation of this system. Numerous adaptatio
Externí odkaz:
https://doaj.org/article/29cdbc69802743d0a4a6e4d9c21ba11b
Autor:
Mary B. Spodnick, Raymond T. Amirault, Trevor T. Towner, Elena I. Varlinskaya, Linda P. Spear, Anushree N. Karkhanis
Publikováno v:
Brain Sciences, Vol 10, Iss 8, p 472 (2020)
Underage alcohol drinking increases the risk of developing alcohol use disorder (AUD). In rodents, adolescent ethanol exposure augments ethanol consumption and anxiety-like behavior while reducing social interaction. However, the underlying mechanism
Externí odkaz:
https://doaj.org/article/94483bbdd3f140a59928020d4666519d
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
Among the numerous consequences of prenatal alcohol exposure (PAE) is an increase in anxiety-like behavior that can prove debilitating to daily functioning. A significant body of literature has linked gestational day 12 (G12) heavy ethanol exposure w
Externí odkaz:
https://doaj.org/article/cf0f5729fb4246d7b91291d8370ed08b
Publikováno v:
Revista Argentina de Ciencias del Comportamiento, Vol 1, Iss 1, Pp 1-12 (2009)
Endogenous opioid systems are implicated in the reinforcing effects of ethanol and may play a substantial role in modulating the central reinforcing effects of ethanol early in ontogeny. This possibility was explored in the present study through the
Externí odkaz:
https://doaj.org/article/0893b7dc7d56485f982a88d8b6070711
Publikováno v:
Dose-Response, Vol 3 (2005)
Low doses of psychoactive drugs often elicit a behavioral profile opposite to that observed following administration of more substantial doses. Our laboratory has observed that these effects are often age-specific in rats. For instance, whereas moder
Externí odkaz:
https://doaj.org/article/505c3f6beb9544599527debdafc3c71f
Autor:
Kathryn R. Przybysz, Mary B. Spodnick, Julia M. Johnson, Elena I. Varlinskaya, Marvin R. Diaz
Publikováno v:
Addiction biologyREFERENCES. 28(1)
Lifelong social impairments are common in individuals with prenatal alcohol exposure (PAE), and preclinical studies have identified gestational day (G)12 as a vulnerable timepoint for producing social deficits following binge-level PAE. While moderat