Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Elena I. Solntseva"'
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 14, Iss 4, Pp 61-65 (2020)
Introduction. Type A receptors activated by gamma-aminobutyric acid (GABAAR) play an inhibitory role in the nervous system due to the generation of chlorine current (IGABA). Penicillin is a sequential blocker of the GABAAR open channel, which can inh
Externí odkaz:
https://doaj.org/article/a1ee34bd109741f09c7e7b86d4f003ec
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 13, Iss 4, Pp 54-64 (2019)
This overview describes how group mGluR1/5 metabotropic glutamate receptors are involved in neurodegenerative diseases; it also touches upon their use as therapeutic targets in animal models. mGluR1/5 are primarily located on the neuronal postsynapti
Externí odkaz:
https://doaj.org/article/de1c153beaf44fc18311659da023ace2
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
The ability of androstane and androstene neurosteroids with modifications at C-17, C-5, and C-3 (compounds 1-9) to influence the functional activity of inhibitory glycine and γ-aminobutyric acid (GABA) receptors was estimated. The glycine- and GABA-
Externí odkaz:
https://doaj.org/article/538935fb3d854a4a936e57561bae6033
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 12, Iss 4, Pp 57-61 (2018)
Introduction. Metabotropic glutamate receptors of group 1 (mGluR1/5) are an important component of the hippocampal inhibitory system. Disturbances of their work lead to manifestation of various pathologies of the nervous system. The search for effect
Externí odkaz:
https://doaj.org/article/1acbe1b6ecc04e0c92003ad52d9a1a1c
Publikováno v:
Hippocampus. 32:552-563
The ability of endogenous neurosteroids (NSs) with pregnane skeleton modified at positions C-3 and C-5 to modulate the functional activity of inhibitory glycine receptors (GlyR) and ionotropic ɣ-aminobutyric acid receptors (GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e133ff475ff40989ba87d7ed8b0ce32d
https://doi.org/10.1002/hipo.23449
https://doi.org/10.1002/hipo.23449
Publikováno v:
Bulletin of Experimental Biology and Medicine
Ivermectin (IVM) belongs to the class of macrocyclic lactones, which is used as an antiparasitic agent. At present, the researchers focus on possibility to use IVM in treatment of certain forms of cancer and viral diseases such as COVID-19. The mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bc0181f30c71ba88b25fb922215a07
https://doi.org/10.1007/s10517-021-05125-3
https://doi.org/10.1007/s10517-021-05125-3
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 224
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter. GABA receptor type A (GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96961e3e4ac4dee8e714d7c3b7fe56a5
https://pubmed.ncbi.nlm.nih.gov/35931327
https://pubmed.ncbi.nlm.nih.gov/35931327
Publikováno v:
Bulletin of Experimental Biology and Medicine. 169:791-794
Chloride current (IGly) evoked by the rapid (600 msec) application of glycine on isolated pyramidal neurons of the rat hippocampus was recorded using the patch clamp technique. We studied the effect of individual or combined application of copper ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119c7726e722e754c660793071bdc45c
https://doi.org/10.1007/s10517-020-04980-w
https://doi.org/10.1007/s10517-020-04980-w
Publikováno v:
Bulletin of Experimental Biology and Medicine. 168:419-422
Whole-cell patch-clamp technique was employed to record chloride ionic current IGABA evoked by fast (600 msec) application of GABA to hippocampal pyramidal neurons and cerebellar Purkinje cells isolated from rat brain. GABA solution in the applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7754609fdebe7b2ea0dfa35237a39ab
https://doi.org/10.1007/s10517-020-04722-y
https://doi.org/10.1007/s10517-020-04722-y
Publikováno v:
Biomolecules
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 791, p 791 (2021)
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 791, p 791 (2021)
Epipregnanolone (3β-hydroxy-5β-pregnan-20-one, Epi) is an endogenous steroid with important physiological effects and high affinity for GABAA receptors. The effect of Epi on GABA-induced chloride current (IGABA) in native neurons has hardly been st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecf271eadaede2e884998df483fbf3b
http://europepmc.org/articles/PMC8225200
http://europepmc.org/articles/PMC8225200