Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elena I. Bukreeva"'
Autor:
Lioubov G. Korotchkina, Elena I. Bukreeva, Andrei V. Gudkov, Zoya N. Demidenko, Olga V. Leontieva, Mikhail V. Blagosklonny
Publikováno v:
Aging (Albany NY)
Transient induction of p53 can cause reversible quiescence and irreversible senescence. Using nutlin-3a (a small molecule that activates p53 without causing DNA damage), we have previously identified cell lines in which nutlin-3a caused quiescence. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19fc300cbcc625978e40d58b4ae9ad5
https://doi.org/10.18632/aging.100160
https://doi.org/10.18632/aging.100160
Autor:
Zoya N. Demidenko, Valery A. Pospelov, Svetlana G. Zubova, Tatiana V. Pospelova, Mikhail V. Blagosklonny, Elena I. Bukreeva
Publikováno v:
Cell Cycle. 8:1888-1895
When the cell cycle is arrested but cellular growth is not, then cells senesce, permanently losing proliferative potential. Here we demonstrated that the duration of cell cycle arrest determines a progressive loss of proliferative capacity. In human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e97d05698104d9914331dc40a7cd911
https://doi.org/10.4161/cc.8.12.8606
https://doi.org/10.4161/cc.8.12.8606
Autor:
Andrei V. Gudkov, Mikhail V. Blagosklonny, Elena I. Bukreeva, Zoya N. Demidenko, Pospelova Tv, Valery A. Pospelov
Publikováno v:
Cell cycle (Georgetown, Tex.). 8(24)
Cellular senescence is currently viewed as a response to DNA damage. In this report, we showed that non-damaging agents such as sodium butyrate-induced p21 and ectopic expression of either p21 or p16 cause cellular senescence without detectable DNA b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca15da0bac72d12f8aa610396075f6f
https://pubmed.ncbi.nlm.nih.gov/19959935
https://pubmed.ncbi.nlm.nih.gov/19959935