Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Elena I Sinauridze"'
Autor:
Ivan D Tarandovskiy, Elena O Artemenko, Mikhail A Panteleev, Elena I Sinauridze, Fazoil I Ataullakhanov
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55688 (2013)
BACKGROUND: Thrombin generation assay is a convenient and widely used method for analysis of the blood coagulation system status. Thrombin generation curve (TGC) is usually bell-shaped with a single peak, but there are exceptions. In particular, TGC
Externí odkaz:
https://doaj.org/article/dc8fd637f39042e993a50f350af1222c
Autor:
Elena I Sinauridze, Alexey N Romanov, Irina V Gribkova, Olga A Kondakova, Stepan S Surov, Aleksander S Gorbatenko, Andrey A Butylin, Mikhail Yu Monakov, Alexey A Bogolyubov, Yuryi V Kuznetsov, Vladimir B Sulimov, Fazoyl I Ataullakhanov
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19969 (2011)
BackgroundThe development of new anticoagulants is an important goal for the improvement of thromboses treatments.ObjectivesThe design, synthesis and experimental testing of new safe and effective small molecule direct thrombin inhibitors for intrave
Externí odkaz:
https://doaj.org/article/a69be1a33b304dbd8675b481fc9eaf89
Publikováno v:
Blood Coagulation & Fibrinolysis. 31:193-197
Thrombin generation test (TGT) is well established tool to research blood coagulation in plasma of hemophilia patients. Traditionally coagulation in this test is triggered by a tissue factor (TF), an extrinsic coagulation pathway activator. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08f548fdfa5aa297f0febe031fd3c6a
https://doi.org/10.1097/mbc.0000000000000898
https://doi.org/10.1097/mbc.0000000000000898
Autor:
Daria V. Borsakova, Larisa D. Koleva, Evgeniy S. Protasov, Fazoil I. Ataullakhanov, Elena I. Sinauridze
Publikováno v:
Scientific Reports. 12
Excessive ammonium blood concentration causes many serious neurological complications. The medications currently used are not very effective. To remove ammonium from the blood, erythrocyte-bioreactors containing enzymes that processing ammonium have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34e5f21552410e1aaffce613f159e6f
https://doi.org/10.1038/s41598-022-09435-y
https://doi.org/10.1038/s41598-022-09435-y
Autor:
S. V. Nazarenko, Elena I. Sinauridze, Yuliya G. Alexandrovich, A. A. Butylin, Daria Borsakova, F. I. Ataullakhanov, E. S. Protasov
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 13:212-224
An increased blood ammonium concentration (hyperammonemia) is toxic to the central nervous system, so removing excess ammonium from the bloodstream is an important task. One of the solutions may be the use of erythrocyte-bioreactors (EBRs) with ammon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5083a39ec59a6f2f934644a8bfb670d
https://doi.org/10.1134/s1990747819030048
https://doi.org/10.1134/s1990747819030048
Publikováno v:
Biochemistry (Moscow). 84:119-136
The review discusses main approaches to searching for new low-molecular-weight inhibitors of coagulation factors IIa, Xa, IXa, and XIa and the results of such studies conducted from 2015 to 2018. For each of these factors, several inhibitors with IC5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ffe4d5b5f55e8db8e34d6104aa267d
https://doi.org/10.1134/s0006297919020032
https://doi.org/10.1134/s0006297919020032
Autor:
Dmitry S. Prudinnik, Elena I. Sinauridze, Soslan S. Shakhidzhanov, Elizaveta A. Bovt, Denis N. Protsenko, Alexander G. Rumyantsev, Fazoil I. Ataullakhanov
Publikováno v:
Biomolecules; Volume 12; Issue 6; Pages: 782
For the first time, the influence of COVID-19 on blood microrheology was studied. For this, the method of filtering erythrocytes through filters with pores of 3.5 μm was used. Filterability was shown to significantly decrease with the increasing sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdf8dcbf63cbaea0ef4be37fceb8f8a
https://doi.org/10.3390/biom12060782
https://doi.org/10.3390/biom12060782
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 276 (2020)
Pharmaceutics
Pharmaceutics
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly developing field. Such erythrocytes can act as carriers that prolong the drug’s action due to its gradual release from the carrier; as bioreactors with encapsula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718290240170fa80eab766125e0f11c9
https://www.mdpi.com/1999-4923/12/3/276
https://www.mdpi.com/1999-4923/12/3/276
Autor:
Stepan S. Surov, Ruzanna A. Ovsepyan, Fazoil I. Ataullakhanov, Maxim M. Lutsenko, Ilya I. Serebriyskiy, Elena I. Sinauridze, Tatiana A. Vuimo, Natalia G. Korotina, Ivan D. Tarandovskiy, Alexander L. Sokolov
Publikováno v:
Talanta. 180:282-291
The actual coagulation status may be reliably measured using only highly sensitive global functional tests; however, they are not numerous and all of them have disadvantages. Thrombodynamics (TD), a novel global coagulation test, is sensitive to hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab933648fa5d34ba310ef8664ae0eca
https://doi.org/10.1016/j.talanta.2017.12.055
https://doi.org/10.1016/j.talanta.2017.12.055
Autor:
Elena N. Lipets, Elena A. Seregina, Fazoil I. Ataullakhanov, Alexander Sergeevich Gorbatenko, Elena I. Sinauridze
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Artificial plasma expanders (PEs) are widely used in modern transfusion medicine. PEs do not contain components of the coagulation system, so their infusion in large volumes causes haemodilution and affects haemostasis. However, the existing informat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bfb5580a82a900cdd80bd9a6bd74df
https://doaj.org/article/cabeb134f4034f4e806afaa83c3cc50a
https://doaj.org/article/cabeb134f4034f4e806afaa83c3cc50a