Výsledky vyhledávání - "Elena I, Anisimova"

Somatic loss of the remaining allele occurs approximately in half of CHEK2-driven breast cancers and is accompanied by a border-line increase of chromosomal instability

Autor: Aglaya G. Iyevleva, Svetlana N. Aleksakhina, Anna P. Sokolenko, Sofia V. Baskina, Aigul R. Venina, Elena I. Anisimova, Ilya V. Bizin, Alexandr O. Ivantsov, Yana V. Belysheva, Alexandra P. Chernyakova, Alexandr V. Togo, Evgeny N. Imyanitov

Publikováno v: Breast Cancer Research and Treatment. 192:283-291

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e086ed9674dd019b4a58a45c41a69c91
https://doi.org/10.1007/s10549-022-06517-3

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Gastric Cancer in BRCA1 Germline Mutation Carriers: Results of Endoscopic Screening and Molecular Analysis of Tumor Tissues

Autor: Ilya V. Bizin, Alexandr A. Bessonov, Mikhail A Maydin, Aldon J. Whitehead, Olga A Volynshchikova, Albina A Avanesyan, Elena I Anisimova, Valeria I. Ni, Alexandr M Scherbakov, Alexandr A. Romanko, Evgeny N. Imyanitov, Oleg B Tkachenko, Grigory A. Raskin, Alexandr O. Ivantsov, Maxim A Kleshchev, Tatiana V. Gorodnova, Ksenia Shelekhova, Robert V Broyde, Anna P. Sokolenko

Publikováno v: Pathobiology. 87:367-374

Introduction: There is some evidence suggesting a link between BRCA1/2 germline mutations and increased risk of gastric cancer. Methods: Endoscopic screening for stomach malignancies was performed in 120 BRCA1 mutation carriers in order to evaluate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d1504816132772956d8f73147c4d397
https://doi.org/10.1159/000511323

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Somatic loss of the remaining allele occurs approximately in half of CHEK2-driven breast cancers and is accompanied by a border-line increase of chromosomal instability

Autor: Aglaya G, Iyevleva, Svetlana N, Aleksakhina, Anna P, Sokolenko, Sofia V, Baskina, Aigul R, Venina, Elena I, Anisimova, Ilya V, Bizin, Alexandr O, Ivantsov, Yana V, Belysheva, Alexandra P, Chernyakova, Alexandr V, Togo, Evgeny N, Imyanitov

Publikováno v: Breast cancer research and treatment. 192(2)

Germline mutations in CHEK2 gene represent the second most frequent cause of hereditary breast cancer (BC) after BRCA1/2 lesions. This study aimed to identify the molecular characteristics of CHEK2-driven BCs.Loss of heterozygosity (LOH) for the rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3699d4a9b75bc9bbbde306245b181aa8
https://pubmed.ncbi.nlm.nih.gov/35020107

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Exome sequencing study of Russian breast cancer patients suggests a predisposing role for USP39

Publikováno v: Breast Cancer Research and Treatment. 179:731-742

Germline variants in known breast cancer (BC) predisposing genes explain less than half of hereditary BC cases. This study aimed to identify missing genetic determinants of BC. Whole exome sequencing (WES) of lymphocyte DNA was performed for 49 Russi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3f247c2393a564cdf3b15604b2bcbe
https://doi.org/10.1007/s10549-019-05492-6

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Frequency and molecular characteristics of PALB2-associated cancers in Russian patients

Autor: Alexandr O. Ivantsov, Anna P. Sokolenko, Elena V. Preobrazhenskaya, Alexandr S. Martianov, Svetlana A Chuinyshena, Olga A. Gorustovich, Alla U Shleykina, Tatjana N Sokolova, Alexandr V. Togo, Ekatherina Sh. Kuligina, Ilya V. Bizin, Elena I Anisimova, Evgeny N. Imyanitov, Alexey M. Belyaev

Publikováno v: International journal of cancerREFERENCES. 148(1)

PALB2 is а high-penetrance gene for hereditary breast cancer (BC). Our study aimed to investigate the spectrum of PALB2 mutations in Russian cancer patients. PALB2 sequencing revealed pathogenic variants in 3/190 (1.6%) young-onset and/or familial a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9630cd6c9459532d0b875b068db3d3f5
https://pubmed.ncbi.nlm.nih.gov/32997802

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Frequency and spectrum of founder and non-founder BRCA1 and BRCA2 mutations in a large series of Russian breast cancer and ovarian cancer patients

Autor: Elena I Anisimova, Ilya V. Bizin, Anna P. Sokolenko, Alexey M. Belyaev, Alexandr A. Bessonov, Svetlana N. Aleksakhina, Elena L. Savonevich, Tatiana N. Sokolova, Tatiana V. Gorodnova, Elena V. Preobrazhenskaya, Ilya A. Stepanov, Petr Krivorotko, Aglaya G. Iyevleva, Valeria I. Ni, Alexandr V. Togo, Evgeny N. Imyanitov, Alexandr A. Romanko, Igor Berlev

Publikováno v: Breast cancer research and treatment. 184(1)

The spectrum of BRCA1 and BRCA2 mutations in Slavic countries is characterized by a high prevalence of founder alleles. We analyzed a large data set of Russian breast cancer (BC) and ovarian cancer (OC) patients, who were subjected to founder mutatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112fe7c2b5a5b8a73150bb04cfcd874a
https://pubmed.ncbi.nlm.nih.gov/32776218

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Gastric Cancer in BRCA1 Germline Mutation Carriers: Results of Endoscopic Screening and Molecular Analysis of Tumor Tissues

Autor: Albina A, Avanesyan, Anna P, Sokolenko, Alexandr O, Ivantsov, Maxim A, Kleshchev, Mikhail A, Maydin, Ilya V, Bizin, Grigory A, Raskin, Ksenia V, Shelekhova, Tatiana V, Gorodnova, Alexandr A, Bessonov, Elena I, Anisimova, Olga A, Volynshchikova, Alexandr A, Romanko, Valeria I, Ni, Robert V, Broyde, Oleg B, Tkachenko, Aldon J, Whitehead, Alexandr M, Scherbakov, Evgeny N, Imyanitov

Publikováno v: Pathobiology : journal of immunopathology, molecular and cellular biology. 87(6)

There is some evidence suggesting a link between BRCA1/2 germline mutations and increased risk of gastric cancer.Endoscopic screening for stomach malignancies was performed in 120 BRCA1 mutation carriers in order to evaluate the probability of detect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::521cae034133bb4f4ca834ecc06d3716
https://pubmed.ncbi.nlm.nih.gov/33161400

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Detection of BRCA1 gross rearrangements by droplet digital PCR

Autor: Ekatherina Sh. Kuligina, Tatiana V. Gorodnova, Evgeny N. Imyanitov, Alla Yu Shleykina, Elena I Anisimova, Alexey M. Belyaev, Evgeny N. Suspitsin, Anna P. Sokolenko, Olga A Zaytseva, Ilya V. Bizin, Elena V. Preobrazhenskaya, Sergey A. Laptiev

Publikováno v: Breast cancer research and treatment. 165(3)

Large genomic rearrangements (LGRs) constitute a significant share of pathogenic BRCA1 mutations. Multiplex ligation-dependent probe amplification (MLPA) is a leading method for LGR detection; however, it is entirely based on the use of commercial ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e83bde10b42c05739e6c5cabc74b84
https://pubmed.ncbi.nlm.nih.gov/28656489

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