Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elena Heider"'
Autor:
Abdulaziz S. AlSaman, Fouad Al Ghamdi, Ahmed K. Bamaga, Nahla AlShaikh, Mohammed Al Muqbil, Osama Muthaffar, Fahad A. Bashiri, Baleegh Ali, Arzu Mulayim, Elena Heider, Abdullah A. Alshahrani, Mohammed A. Al Muhaizea
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Duchenne muscular dystrophy (DMD) is a rare neuromuscular disorder that is characterized by progressive muscle weakness, resulting in disability and premature death. Onset of symptoms typically occurs at 2–3 years of age, and disease progression is
Externí odkaz:
https://doaj.org/article/48f3a8dd2e8649f4b391f6da29efacd2
Autor:
Viktoria Marquardt, Gunars Duburs, Christopher Golz, Dirk Flötgen, Daniel Längle, Oliver Koch, Carsten Strohmann, Iveta Luntena, Elena Heider, Brigita Vigante, Dennis Schade
Publikováno v:
European journal of medicinal chemistry. 95
Targeting TGFβ/Smad signaling is an attractive strategy for several therapeutic applications given its role as a key player in many pathologies, including cancer, autoimmune diseases and fibrosis. The class of b-annelated 1,4-dihydropyridines (DHPs)
Publikováno v:
ACS chemical biology. 10(1)
Targeting functional, non-catalytic domains of protein kinases or other proteins is an emerging field in chemical biology research. Non-ATP competitive kinase inhibitors allow for the investigation of active-site independent functions, e.g., the biol