Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elena Harden"'
Autor:
Jason C. Fleming, Christian H. Ottensmeier, Stephen M. Thirdborough, Jana Stasakova, Oliver Wood, Veronika Jenei, Christopher H. Woelk, Kate L. Perry, Jeongmin Woo, Elena Harden, Gareth J. Thomas
Publikováno v:
Cancer Research
Antibodies that block T-cell–regulatory checkpoints have recently emerged as a transformative approach to cancer treatment. However, the clinical efficacy of checkpoint blockade depends upon inherent tumor immunogenicity, with variation in infiltra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d8c6306b7ef1bbce160e71a510e223
https://doi.org/10.1158/0008-5472.can-15-3121
https://doi.org/10.1158/0008-5472.can-15-3121
Autor:
Patrick J. Duriez, John P. Tite, Kinga Karbowniczek, Jon Extance, Christian H. Ottensmeier, Chuan Wang, Freda K. Stevenson, Alexandra J. Allen, Lisa J. Caproni, Natalia Savelyeva, Elena Harden, Gessa Sugiyarto, Leon Douglas, Ifeayinwa Orefo, Paul Rothwell
Publikováno v:
Cancer Immunology, Immunotherapy
Vaccination with DNA that encodes cancer antigens is a simple and convenient way to raise immunity against cancer and has already shown promise in the clinical setting. Conventional plasmid DNA is commonly used which together with the encoded antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88b8a6011c6e01367a8829eae4f8253
https://pubmed.ncbi.nlm.nih.gov/29330557
https://pubmed.ncbi.nlm.nih.gov/29330557
Autor:
Natalia, Savelyeva, Alex, Allen, Warayut, Chotprakaikiat, Elena, Harden, Jantipa, Jobsri, Rosemary, Godeseth, Yidao, Wang, Freda, Stevenson, Christian, Ottensmeier
Publikováno v:
Current topics in microbiology and immunology. 405
In the last decade, immunotherapy with monoclonal antibodies targeting immunological check points has become a breakthrough therapeutic modality for solid cancers. However, only up to 50 % of patients benefit from this powerful approach. For others v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::353bbc59912bbd1510c37535e07f5251
https://pubmed.ncbi.nlm.nih.gov/27704269
https://pubmed.ncbi.nlm.nih.gov/27704269
Publikováno v:
European Journal of Immunology. 41:2447-2456
For long-term attack on tumor cells in patients with prostate cancer, induction of cytolytic T cells is desirable. Several lineage-specific target proteins are known and algorithms have identified candidate MHC class I-binding peptides, particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef91a148d0d9286310ee63efc5f6e77
https://doi.org/10.1002/eji.201141518
https://doi.org/10.1002/eji.201141518
Autor:
Jantipa Jobsri, Christian H. Ottensmeier, Duc Bui-Minh, Victor Klimyuk, Warayut Chotprakaikiat, Freda K. Stevenson, Natalia Savelyeva, Yuri Gleba, Elena Harden, Federica Cavallo, Alex Allen
Publikováno v:
Oncoimmunology
Passive antibody therapy for cancer is an effective but costly treatment modality. Induction of therapeutically potent anticancer antibodies by active vaccination is an attractive alternative but has proven challenging in cancer due to tolerogenic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6984974243e4772bf91480a2e3238c5c
https://pubmed.ncbi.nlm.nih.gov/27471642
https://pubmed.ncbi.nlm.nih.gov/27471642