Multiscale networks in multiple sclerosis

Autor: Keith E. Kennedy, Nicole Kerlero de Rosbo, Antonio Uccelli, Maria Cellerino, Federico Ivaldi, Paola Contini, Raffaele De Palma, Hanne F. Harbo, Tone Berge, Steffan D. Bos, Einar A. Høgestøl, Synne Brune-Ingebretsen, Sigrid A. de Rodez Benavent, Friedemann Paul, Alexander U. Brandt, Priscilla Bäcker-Koduah, Janina Behrens, Joseph Kuchling, Susanna Asseyer, Michael Scheel, Claudia Chien, Hanna Zimmermann, Seyedamirhosein Motamedi, Josef Kauer-Bonin, Julio Saez-Rodriguez, Melanie Rinas, Leonidas G. Alexopoulos, Magi Andorra, Sara Llufriu, Albert Saiz, Yolanda Blanco, Eloy Martinez-Heras, Elisabeth Solana, Irene Pulido-Valdeolivas, Elena H. Martinez-Lapiscina, Jordi Garcia-Ojalvo, Pablo Villoslada

Publikováno v: PLoS Computational Biology, Vol 20, Iss 2 (2024)

Externí odkaz: https://doaj.org/article/7df2ffcbb7b94c3292245134dde36b5c

Magnetic resonance markers of tissue damage related to connectivity disruption in multiple sclerosis

Autor: Elisabeth Solana, Eloy Martinez-Heras, Elena H. Martinez-Lapiscina, Maria Sepulveda, Nuria Sola-Valls, Nuria Bargalló, Joan Berenguer, Yolanda Blanco, Magi Andorra, Irene Pulido-Valdeolivas, Irati Zubizarreta, Albert Saiz, Sara Llufriu

Publikováno v: NeuroImage: Clinical, Vol 20, Iss , Pp 161-168 (2018)

Patients with multiple sclerosis (MS) display reduced structural connectivity among brain regions, but the pathogenic mechanisms underlying network disruption are still unknown. We aimed to investigate the association between the loss of diffusion-ba

Externí odkaz: https://doaj.org/article/678b6a48ec624e6a9b6d9df9d9d54a91

Usefulness of optical coherence tomography to distinguish optic neuritis associated with AQP4 or MOG in neuromyelitis optica spectrum disorders

Autor: Elena H. Martinez-Lapiscina, Maria Sepulveda, Ruben Torres-Torres, Salut Alba-Arbalat, Sara Llufriu, Yolanda Blanco, Ana M. Guerrero-Zamora, Nuria Sola-Valls, Santiago Ortiz-Perez, Pablo Villoslada, Bernardo Sanchez-Dalmau, Albert Saiz

Publikováno v: Therapeutic Advances in Neurological Disorders, Vol 9 (2016)

Externí odkaz: https://doaj.org/article/e96b17904ef24bf78850acec09e74854

Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders

Autor: Frederike Cosima Oertel, Hanna G Zimmermann, Seyedamirhosein Motamedi, Claudia Chien, Orhan Aktas, Philipp Albrecht, Marius Ringelstein, Anitha Dcunha, Lekha Pandit, Elena H Martinez-Lapiscina, Bernardo Sanchez-Dalmau, Pablo Villoslada, Jacqueline Palace, Adriana Roca-Fernández, Maria Isabel Leite, Srilakshmi M Sharma, Letizia Leocani, Marco Pisa, Marta Radaelli, Marco Aurélio Lana-Peixoto, Mariana Andrade Fontenelle, Joachim Havla, Fereshteh Ashtari, Rahele Kafieh, Alireza Dehghani, Mohsen Pourazizi, Romain Marignier, Alvaro Cobo-Calvo, Nasrin Asgari, Anu Jacob, Saif Huda, Yang Mao-Draayer, Ari J Green, Rachel Kenney, Michael R Yeaman, Terry J Smith, Lawrence Cook, Alexander U Brandt, Friedemann Paul, Axel Petzold

Publikováno v: Oertel, F C, Zimmermann, H G, Motamedi, S, Chien, C, Aktas, O, Albrecht, P, Ringelstein, M, Dcunha, A, Pandit, L, Martinez-Lapiscina, E H, Sanchez-Dalmau, B, Villoslada, P, Palace, J, Roca-Fernández, A, Leite, M I, Sharma, S M, Leocani, L, Pisa, M, Radaelli, M, Lana-Peixoto, M A, Fontenelle, M A, Havla, J, Ashtari, F, Kafieh, R, Dehghani, A, Pourazizi, M, Marignier, R, Cobo-Calvo, A, Asgari, N, Jacob, A, Huda, S, Mao-Draayer, Y, Green, A J, Kenney, R, Yeaman, M R, Smith, T J, Cook, L, Brandt, A U, Paul, F & Petzold, A 2023, ' Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders ', Journal of Neurology, Neurosurgery and Psychiatry, vol. 94, no. 7, jnnp-2022-330608, pp. 560-566 . https://doi.org/10.1136/jnnp-2022-330608
Journal of Neurology, Neurosurgery and Psychiatry. BMJ Publishing Group
Journal of Neurology, Neurosurgery & Psychiatry, 2023 [Peer Reviewed Journal]

BackgroundThe novel optic neuritis (ON) diagnostic criteria include intereye differences (IED) of optical coherence tomography (OCT) parameters. IED has proven valuable for ON diagnosis in multiple sclerosis but has not been evaluated in aquaporin-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c0fe50156a84f8fad24865d64a3906
https://research.vumc.nl/en/publications/a5fcb6dd-7796-4a8a-a9b1-6dc6d759c1ba

Predicting disease severity in Multiple Sclerosis using multimodal data and machine learning

Autor: Magi Andorra, Ana Freire, Irati Zubizarreta, Nicole Kerlero de Rosbo, Steffan D. Bos, Melanie Rinas, Einar A. Høgestøl, Sigrid A. Rodez Benavent, Tone Berge, Synne Brune-Ingebretse, Federico Ivaldi, Maria Cellerino, Matteo Pardini, Gemma Vila, Irene Pulido-Valdeolivas, Elena H. Martinez-Lapiscina, Sara Llufriu, Albert Saiz, Yolanda Blanco, Eloy Martinez-Heras, Elisabeth Solana, Priscilla Bäcker-Koduah, Janina Behrens, Joseph Kuchling, Susanna Asseyer, Michael Scheel, Claudia Chien, Hanna Zimmermann, Seyedamirhosein Motamedi, Joseph Kauer-Bonin, Alex Brandt, Julio Saez-Rodriguez, Leonidas Alexopoulos, Friedemann Paul, Hanne F Harbo, Hengameh Shams, Jorge Oksenberg, Antonio Uccelli, Ricardo Baeza-Yates, Pablo Villoslada

Background Multiple Sclerosis patients would benefit from machine learning algorithms that integrates clinical, imaging, and multimodal biomarkers to define the risk of disease activity. Methods We have analyzed a prospective multi-centric cohort of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c55f9351aa41992f5d702acbff86d86
https://doi.org/10.21203/rs.3.rs-2414345/v1