Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Elena Garre"'
Autor:
Maria Carmen Leiva, Anna Gustafsson, Elena Garre, Anders Ståhlberg, Anikó Kovács, Khalil Helou, Göran Landberg
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background The tumor microenvironment clearly influences cancer progressing properties but less is known about how individual cancer microenvironments potentially moderate cancer treatment effects. By cultivating and treating cancer cell lin
Externí odkaz:
https://doaj.org/article/41fdf1298b28424aad7fdf8966ef5a49
Autor:
Anna Gustafsson, Elena Garre, Maria Carmen Leiva, Simona Salerno, Anders Ståhlberg, Göran Landberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Three-dimensional cell culture platforms based on decellularised patient-based microenvironments provide in vivo-like growth conditions allowing cancer cells to interact with intact structures and components of the surrounding tissue. A pati
Externí odkaz:
https://doaj.org/article/c7aee6255bcd481eb4ae53bb386c2cb9
Autor:
Claire A Walsh, Nina Akrap, Elena Garre, Ylva Magnusson, Hannah Harrison, Daniel Andersson, Emma Jonasson, Svanheidur Rafnsdottir, Hani Choudhry, Francesca Buffa, Jiannis Ragoussis, Anders Ståhlberg, Adrian Harris, Göran Landberg
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236187 (2020)
The definitive characterization of common cancer stem cell (CSCs) subpopulations in breast cancer subtypes with distinct genotypic and phenotypic features remains an ongoing challenge. In this study, we have used a non-biased genome wide screening ap
Externí odkaz:
https://doaj.org/article/e1715fcef590406caf5e91eba60549d3
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007563 (2018)
RNA-binding proteins (RBPs) establish the cellular fate of a transcript, but an understanding of these processes has been limited by a lack of identified specific interactions between RNA and protein molecules. Using MS2 RNA tagging, we have purified
Externí odkaz:
https://doaj.org/article/9c437fdc17f2432891f69631e4d09b3b
Autor:
Luisa Statello, Marco Maugeri, Elena Garre, Muhammad Nawaz, Jessica Wahlgren, Alexandros Papadimitriou, Christina Lundqvist, Lennart Lindfors, Anna Collén, Per Sunnerhagen, Marco Ragusa, Michele Purrello, Cinzia Di Pietro, Natalie Tigue, Hadi Valadi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195969 (2018)
The RNA that is packaged into exosomes is termed as exosomal-shuttle RNA (esRNA); however, the players, which take this subset of RNA (esRNA) into exosomes, remain largely unknown. We hypothesized that RNA binding proteins (RBPs) could serve as key p
Externí odkaz:
https://doaj.org/article/b2cf47c08cfc43138c14c6816952d28f
Autor:
Xiaoxue Yang, Yi Shen, Elena Garre, Xinxin Hao, Daniel Krumlinde, Marija Cvijović, Christina Arens, Thomas Nyström, Beidong Liu, Per Sunnerhagen
Publikováno v:
PLoS Genetics, Vol 10, Iss 11, p e1004763 (2014)
To reduce expression of gene products not required under stress conditions, eukaryotic cells form large and complex cytoplasmic aggregates of RNA and proteins (stress granules; SGs), where transcripts are kept translationally inert. The overall compo
Externí odkaz:
https://doaj.org/article/97894484b2ff4e8f824d7d0977461841
Autor:
Elena Garre, Lorena Romero-Santacreu, Manuela Barneo-Muñoz, Ana Miguel, José E Pérez-Ortín, Paula Alepuz
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61240 (2013)
The expression of ribosomal protein (RP) genes requires a substantial part of cellular transcription, processing and translation resources. Thus, the RP expression must be tightly regulated in response to conditions that compromise cell survival. In
Externí odkaz:
https://doaj.org/article/8686b0d3ab394ccdbaa7feaa6b24842c
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85404 (2013)
The whole genome analysis has demonstrated that wine yeasts undergo changes in promoter regions and variations in gene copy number, which make them different to lab strains and help them better adapt to stressful conditions during winemaking, where o
Externí odkaz:
https://doaj.org/article/216a0422ad4441c3b24e0d07547c89e3
Autor:
Joakim Håkansson, Anna Gustafsson, Elena Garre, Anders Ståhlberg, Göran Landberg, Maria Carmen Leiva, Yalda Bogestål, Andreas Svanström
Publikováno v:
Journal of Cellular Physiology
Breast cancer is a heterogeneous disease where the tumor microenvironment, including extracellular components, plays a crucial role in tumor progression, potentially modulating treatment response. Different approaches have been used to develop three
Autor:
Paul A. Fitzpatrick, Anna Gustafsson, Pernilla Gregersson, Elena Garre, Anders Ståhlberg, Göran Landberg, Maria del Carmen Leiva-Arrabal
Publikováno v:
Cancer Research. 80:P1-04
Despite great efficiencies of today’s anti-cancer therapies in breast cancer medicine, recurrences and metastasis still remains a major challenge. The tumor initiating population of cancer stem cells (CSC) is believed to promote metastasis and drug