Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Elena Garitta"'
Autor:
Tiziano Mazza, Theodoros I. Roumeliotis, Elena Garitta, David Drew, S. Tamir Rashid, Cesare Indiveri, Jyoti S. Choudhary, Kenneth J. Linton, Konstantinos Beis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Multidrug resistance-associated protein 2 (MRP2/ABCC2) is a polyspecific efflux transporter of organic anions expressed in hepatocyte canalicular membranes. MRP2 dysfunction, in Dubin-Johnson syndrome or by off-target inhibition, for example
Externí odkaz:
https://doaj.org/article/fdd5bced4bd2462399776434cd49d9e5
Autor:
Samuel J.I. Blackford, Tracy T.L. Yu, Michael D.A. Norman, Adam M. Syanda, Michail Manolakakis, Dariusz Lachowski, Ziqian Yan, Yunzhe Guo, Elena Garitta, Federica Riccio, Geraldine M. Jowett, Soon Seng Ng, Santiago Vernia, Armando E. del Río Hernández, Eileen Gentleman, S. Tamir Rashid
Publikováno v:
Gentleman, E, Rashid, T, Blackford, S, Jowett, G, Yan, Z, Yu, T, Norman, M, Guo, Y, Syanda, A, Riccio, F, Ng, S S, Manolakakis, M, Lachowski, D, Garrita, E, Vernia, S & de Rio Hernandez, A 2023, ' RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling ', Biomaterials, vol. 293, 121982 . https://doi.org/10.1016/j.biomaterials.2022.121982
Human pluripotent stem cell-derived hepatocytes (hPSC-Heps) may be suitable for treating liver diseases, but differentiation protocols often fail to yield adult-like cells. We hypothesised that replicating healthy liver niche biochemical and biophysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d9ea300a57246addd8c417a8dad89a
http://hdl.handle.net/10044/1/102659
http://hdl.handle.net/10044/1/102659