Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Elena Gabusi"'
Autor:
Enrica Marchionni, Maria Rosaria D'Apice, Viviana Lupo, Giovanna Lattanzi, Elisabetta Mattioli, Gina Lisignoli, Elena Gabusi, Gerardo Pepe, Manuela Helmer Citterich, Elena Campione, Anna Maria Nardone, Paola Spitalieri, Noemi Pucci, Dario Cocciadiferro, Eliseo Picchi, Francesco Garaci, Antonio Novelli, Giuseppe Novelli
Publikováno v:
Bone Reports, Vol 19, Iss , Pp 101728- (2023)
COL2A1 gene encodes the alpha-1 chain of type-II procollagen. Heterozygous pathogenic variants are associated with the broad clinical spectrum of genetic diseases known as type-II collagenopathies. We aimed to characterize the NM_001844.5:c.1330G>A;p
Externí odkaz:
https://doaj.org/article/7aab59cb6a3344baa1cce4c1308ebddc
Visible light-mediated cross-linking of injectable gellan gum hydrogels embedding human chondrocytes
Autor:
Diego Trucco, Lorenzo Vannozzi, Elena Gabusi, Enrico Lenzi, Cristina Manferdini, Alessia Bacci, Liliana Agresti, Maria Rosaria Pascale, Sandra Cristino, Gina Lisignoli, Leonardo Ricotti
Publikováno v:
Carbohydrate Polymer Technologies and Applications, Vol 6, Iss , Pp 100382- (2023)
Gellan gum, a polysaccharide with structural similarities to glycosaminoglycans, is gaining attention in cartilage tissue engineering. It can be chemically modified with methacrylic moieties to produce a photo-crosslinkable formulation, called methac
Externí odkaz:
https://doaj.org/article/dfd1930c6b124e61afbbce56ac04c5f5
Autor:
Lia Pulsatelli, Cristina Manferdini, Elena Gabusi, Erminia Mariani, Francesco Ursini, Jacopo Ciaffi, Riccardo Meliconi, Gina Lisignoli
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-7 (2022)
Abstract Background Progressive pseudorheumatoid dysplasia (PPRD) is a rare autosomal recessive non-inflammatory skeletal disease with childhood onset and is characterized by a progressive chondropathy in multiple joints, and skeletal abnormalities.
Externí odkaz:
https://doaj.org/article/d577df58988146d787a47887a8db1c04
Autor:
Elisa Schena, Elisabetta Mattioli, Chiara Peres, Laura Zanotti, Paolo Morselli, Patricia Iozzo, Maria Angela Guzzardi, Chiara Bernardini, Monica Forni, Salvatore Nesci, Massimiliano Caprio, Carolina Cecchetti, Uberto Pagotto, Elena Gabusi, Luca Cattini, Gina Lisignoli, William Blalock, Alessandra Gambineri, Giovanna Lattanzi
Publikováno v:
Cells, Vol 12, Iss 22, p 2586 (2023)
Type-2 Familial Partial Lipodystrophy (FPLD2), a rare lipodystrophy caused by LMNA mutations, is characterized by a loss of subcutaneous fat from the trunk and limbs and excess accumulation of adipose tissue in the neck and face. Several studies have
Externí odkaz:
https://doaj.org/article/ce99735e236c4a80ae4251f9d5cb37de
Autor:
Cristina Manferdini, Elena Gabusi, Yasmin Saleh, Enrico Lenzi, Giovanni D’Atri, Leonardo Ricotti, Gina Lisignoli
Publikováno v:
Cells, Vol 11, Iss 24, p 3969 (2022)
This systematic review is focused on the main characteristics of the hydrogels used for embedding the mesenchymal stromal cells (MSCs) in in vitro/ex vivo studies, in vivo OA models and clinical trials for favoring cartilage regeneration in osteoarth
Externí odkaz:
https://doaj.org/article/e21fd238f66c404e8f42564640a9e0fd
Autor:
Elena Gabusi, Enrico Lenzi, Cristina Manferdini, Paolo Dolzani, Marta Columbaro, Yasmin Saleh, Gina Lisignoli
Publikováno v:
Gels, Vol 8, Iss 12, p 766 (2022)
Autophagy is a cellular process that contributes to the maintenance of cell homeostasis through the activation of a specific path, by providing the necessary factors in stressful and physiological situations. Autophagy plays a specific role in chondr
Externí odkaz:
https://doaj.org/article/8778f8b833334b68a4edb7082d91c692
Autor:
Cristina Manferdini, Diego Trucco, Yasmin Saleh, Elena Gabusi, Paolo Dolzani, Enrico Lenzi, Lorenzo Vannozzi, Leonardo Ricotti, Gina Lisignoli
Publikováno v:
Gels, Vol 8, Iss 6, p 382 (2022)
Articular cartilage is known to have limited intrinsic self-healing capacity when a defect or a degeneration process occurs. Hydrogels represent promising biomaterials for cell encapsulation and injection in cartilage defects by creating an environme
Externí odkaz:
https://doaj.org/article/14e668506ef1488281c467583133013a
Publikováno v:
Biology, Vol 10, Iss 7, p 579 (2021)
Scaffolds associated with mesenchymal stem cell (MSC) derivatives, such as extracellular vesicles (EVs), represent interesting carriers for bone regeneration. This systematic review aims to analyze in vitro and in vivo studies that report the effects
Externí odkaz:
https://doaj.org/article/c372a662b9f745369eafc98bd1c23f85
Autor:
Cristina Manferdini, Yasmin Saleh, Paolo Dolzani, Elena Gabusi, Diego Trucco, Giuseppe Filardo, Gina Lisignoli
Publikováno v:
Biology, Vol 9, Iss 12, p 459 (2020)
There is a lack ofin vitromodels able to properly represent osteoarthritis (OA) synovial tissue (ST). We aimed to characterize OA ST and to investigate whether a mechanical or enzymatic digestion procedures influence synovial cell functional heteroge
Externí odkaz:
https://doaj.org/article/da36a26ff47942e289c7c8121d815b95
Autor:
Diego Trucco, Laura Riacci, Lorenzo Vannozzi, Cristina Manferdini, Lorenzo Arrico, Elena Gabusi, Gina Lisignoli, Leonardo Ricotti
Publikováno v:
Macromolecular bioscience. 22(10)
A stable adhesion to the cartilage is a crucial requisite for hydrogels used for cartilage regeneration. Indeed, a weak interface between the tissue and the implanted material may produce a premature detachment and thus the failure of the regeneratio