Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Elena G Novoselova"'
Autor:
Elena G Novoselova, Sergey M Lunin, Olga V Glushkova, Maxim O Khrenov, Svetlana B Parfenyuk, Nadezhda M Zakharova, Evgeny E Fesenko
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197601 (2018)
In the present work, we aimed to study the effects of free and polybutylcyanoacrylate nanoparticle-bound thymulin on immune cell activity in mice with chronic inflammation. NF-κB, MAPK, and PKC-θ signaling pathway activity was assessed, alongside H
Externí odkaz:
https://doaj.org/article/3e874b0d50164fc5bb0961563c22cc2a
Autor:
Elena G. Novoselova
Publikováno v:
Cellular Physiology and Biochemistry, Vol 58, Iss 2, Pp 144-155 (2024)
Diabetes mellitus type 1 (T1D) and type 2 (T2D) develop due to dysfunction of the Langerhans islet β-cells in the pancreas, and this dysfunction is mediated by oxidative, endoplasmic reticulum (ER), and mitochondrial stresses. Although the two types
Externí odkaz:
https://doaj.org/article/54c57daae541465c9425acbf9c77c98f
Autor:
Sergey M. Lunin, Elena G. Novoselova, Olga V. Glushkova, Svetlana B. Parfenyuk, Tatyana V. Novoselova, Maxim O. Khrenov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4109 (2022)
Pathways regulating cell senescence and cell cycle underlie many processes associated with ageing and age-related pathologies, and they also mediate cellular responses to exposure to stressors. Meanwhile, there are central mechanisms of the regulatio
Externí odkaz:
https://doaj.org/article/3f8ddfddfee343c6829e0a90fdf5380d
Autor:
Elena G. Novoselova, Olga V. Glushkova, Sergey M. Lunin, Maxim O. Khrenov, Svetlana B. Parfenyuk, Tatyana V. Novoselova, Mars G. Sharapov, Vladimir I. Novoselov, Evgeny E. Fesenko
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Type 1 diabetes is associated with the destruction of pancreatic beta cells, which is mediated via an autoimmune mechanism and consequent inflammatory processes. In this article, we describe a beneficial effect of peroxiredoxin 6 (PRDX6) in a type 1
Externí odkaz:
https://doaj.org/article/182ccb597a9c4da79dbf9e5c9605cbfb
Publikováno v:
Modern Electronic Materials, Vol 2, Iss 1, Pp 29-32 (2016)
Radiation-induced modification of semiconductors is achieved by controlled introduction of intrinsic structural and impurity defects. Conventionally, introduction of radiation-induced defects is used as an efficient tool for controlling the lifetime
Externí odkaz:
https://doaj.org/article/ad047768cd084f95be47b007cfd781d5
Autor:
Elena G, Novoselova, Olga V, Glushkova, Maxim O, Khrenov, Sergey M, Lunin, Tatyana V, Novoselova, Svetlana B, Parfenuyk
Publikováno v:
Biochemistry (Moscow). 86:1579-1589
The review discusses information on the development of type 1 diabetes mellitus (T1D) as a systemic autoimmune and inflammatory disease. Focus of the review is on the role of innate immune system, including activation of some signaling cascades, cyto
Autor:
S. B. Parfenyuk, Olga V. Glushkova, Sergey M Lunin, T. V. Novoselova, Elena G Novoselova, E. E. Fesenko, Maxim O. Khrenov
Publikováno v:
Doklady Biological Sciences. 493:124-127
The role of two heat shock proteins, Hsp70 and Hsp90α, on stress response in mice with severe diabetes mellitus induced by a high dose of alloxan (500 mg/kg body weight), as well as in RIN-m5F β cells cultured in the presence of cytokines (IL-1 and
Autor:
Elena G. Novoselova, Mars G. Sharapov, Sergey M. Lunin, Svetlana B. Parfenyuk, Maxim O. Khrenov, Elvira K. Mubarakshina, Anna A. Kuzekova, Tatyana V. Novoselova, Ruslan G. Goncharov, Olga V. Glushkova
Publikováno v:
Antioxidants; Volume 10; Issue 12; Pages: 1951
Antioxidants
Antioxidants, Vol 10, Iss 1951, p 1951 (2021)
Antioxidants
Antioxidants, Vol 10, Iss 1951, p 1951 (2021)
Although many different classes of antioxidants have been evaluated as radioprotectors, none of them are in widespread clinical use because of their low efficiency. The goal of our study was to evaluate the potential of the antioxidant protein peroxi
Autor:
Elena G Novoselova, Tatiana V. Novoselova, Olga V. Glushkova, Sergey M Lunin, S. B. Parfenyuk, Maxim O. Khrenov
Publikováno v:
Cellular Immunology. 336:20-27
Characteristics of the mouse model of relapsing-remitting experimental autoimmune encephalomyelitis (rEAE) closely resemble manifestations of multiple sclerosis in humans. In the present study, we investigated the mechanisms of inflammatory response,
Autor:
Vladimir I. Novoselov, S. B. Parfenyuk, Mars G. Sharapov, Olga V. Glushkova, Sergey M Lunin, A. E. Gordeeva, Maxim O. Khrenov, T. V. Novoselova, Elena G Novoselova, E. E. Fesenko
Publikováno v:
International Journal of Immunopathology and Pharmacology
Protective effects of peroxiredoxin 6 (PRDX6) in RIN-m5F β-cells and of thymulin in mice with alloxan-induced diabetes were recently reported. The present work was aimed at studying the efficiency of thymulin and PRDX6 in a type 1 diabetes mellitus